Cytotoxicity and hemostatic activity of chitosan/carrageenan composite wound healing dressing for traumatic hemorrhage

Polyvinyl Alcohol/Chitosan and Polyvinyl Alcohol/Ag@MOF Bilayer Hydrogel for Tissue Engineering Applications

“…In vitro biodegradation of wound dressings was tested by calculating the rate of weight loss in the presence of hydrolases encountered by the dressings at the site of injury [ 17 ]. The sample (2 × 1 cm 2 ) was placed in phosphate-buffered saline (PBS) containing 10,000 U/mL lysozyme for enzymatic degradation.…”

“…Chitosan is a polycationic natural polysaccharide biopolymer widely used in the manufacture of hydrogels [ 16 ]. Chitosan is a biocompatibility material with non-toxic and antibacterial activity [ 17 ]. The amino group on the chitosan interacts with the negative charge on the red blood cell membrane, which cause it to have an anticoagulation effect.…”

An injectable serotonin–chondroitin sulfate hydrogel for bio-inspired hemostatic adhesives with high wound healing capability

“…The blood cell and platelet adhesive tests were conducted according to the literature. 52,53 The whole blood was dropping on the hydrogel and then incubated at 37 ºС for 30 min. After incubation, the sample was washed with PBS (pH 7.4) solution for 3 times followed by fixation in glutaraldehyde (2.5 %) for one night.…”

A Review on Revolutionary Natural Biopolymer-Based Aerogels for Antibacterial Delivery

“…In vitro wound healing analysis confirmed that the aerogel composite increases the migration rate on fibroblast cells and enhances the proliferation of cells, which was observed from the result of covered distance for keratinocytes [ 60 ]. Biranje et al [ 162 ] used chitosan/seaweed aerogel composite for wound dressing to promote hemostasis of the wounds and tissue growth, which is required during hemorrhaging. In vitro evaluation of hemostatic properties was done using human thrombin-anti-thrombin assay.…”