D - Penicillamine-induced pemphigus foliaceus with autoantibodies to desmoglein-1 in a patient with mixed connective tissue disease

Diagnosis and Clinical Features of Pemphigus Foliaceus

“…The most commonly implicated drug is penicillamine, which is a chelating agent used to treat Wilson’s disease, lead and arsenic poisoning, and severe active rheumatoid arthritis (15). Drug-associated cases may persist or quickly clear after the offending agent is withdrawn.…”

D-Penicillamine-induced Pemphigus Vulgaris in a Patient with Scleroderma-Rheumatoid Arthritis Overlap Syndrome

“…Most reports of penicillamine-induced pemphigus are in patients with RA, 10 cases have been reported in patients with SSc (1) and only one case is described in a patient with mixed connective tissue disease (11). This is the first publication regarding a patient with SSc-RA overlap syndrome.…”

A case of pemphigus vulgaris possibly triggered by quinolones

“…Today it is known that the onset and progress of pemphigus possibly depends on the interaction between genetic background and various exogenous factors, including diet, drugs and other environmental factors 1 …”

“…Today it is known that the onset and progress of pemphigus possibly depends on the interaction between genetic background and various exogenous factors, including diet, drugs and other environmental factors. 1 Drug-induced pemphigus was first described by Degos et al . in 1969 when they reported a man suffering from Wilson's disease in whom pemphigus appeared after treatment with d -penicillamine.…”