Dabigatran-induced esophageal injury: a case report

Zhang, Jingrui; Li, Changyi; Li, Songnan; Dong, Jianzeng; Ma, Changsheng

doi:10.1097/cm9.0000000000001173

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…[10][11][12] Five patients (18.52%) took proton pump inhibitors (PPI) while taking dabigatran. [10][11][12][13][14]…”

Section: Clinical Informationmentioning

confidence: 99%

Analysis of the clinical characteristics of dabigatran-induced oesophagitis

Zhou

Su²,

et al. 2021

Eur J Hosp Pharm

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Objectives Dabigatran-induced oesophagitis has emerged in recent years. However, the incidence and clinical characteristics of patients with dabigatran-induced oesophagitis have not yet been clarified. The aim of this study was to examine the clinical characteristics of the disease. Methods A retrospective analysis was undertaken of the literature on dabigatran-induced oesophagitis in Chinese and English from 2008 onwards. Results There were 20 men (74.07%) and seven women (25.93%) in the study; their median age was 75 years (range 37-90). The main clinical symptoms were dysphagia (42.31%), odynophagia (26.92%), retrosternal pain (23.08%) and heartburn (23.08%). Endoscopy mainly showed sloughing mucosal casts (14 cases, 56%), ulcers (8 cases, 32%) and erosion (6 cases, 24%). The main injury sites were the mid to lower oesophagus (32%) and the mid oesophagus (32%). Withdrawal of dabigatran or giving the correct medication regimen resulted in rapid recovery of clinical symptoms from 1 day in some patients and up to 4 weeks, and mucosal recovery (2-5 weeks) in a median time of 3 weeks (range 0.29-48) in all patients. Conclusions Oesophagitis is a rare complication of dabigatran with a good prognosis. Patients should be given proper medication instructions to prevent the occurrence of dabigatran-induced oesophagitis.

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“…[10][11][12] Five patients (18.52%) took proton pump inhibitors (PPI) while taking dabigatran. [10][11][12][13][14]…”

Section: Clinical Informationmentioning

confidence: 99%

Analysis of the clinical characteristics of dabigatran-induced oesophagitis

Zhou

Su²,

et al. 2021

Eur J Hosp Pharm

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“…These phenomena indicate that interphase layer possesses a good electrochemical stability in electrolyte and has negligible effects on H + and Zn 2 + intercalation/deintercalation reactions of NH 4 V 4 O 10 . [50] 5(c, d) and Figure S15 (Supporting Information) show the rate performances of modified Zn/NH 4 V 4 O 10 and pristine Zn/NH 4 V 4 O 10 batteries. At 0.2 A g À 1 , the discharge specific capacity of modified Zn/NH 4 V 4 O 10 battery higher than that of Zn/NH 4 V 4 O 10 battery (351 mAh g À 1 ) is 399 mAh g À 1 .…”

Section: Chemistryselectmentioning

confidence: 99%

A Simple Route to Fabricate an Artificial Interface Protective Layer on a Zn Anode for Aqueous Zn‐Ion Batteries

Guo

2022

ChemistrySelect

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Aqueous Zn‐ion batteries (AZIBs) have attracted lots of attention due to good eco‐friendly, safety and high energy density. However, the dendritic growth and side reactions on Zn anodes have affected the safety and stability of AZIBs. In this paper, an artificial interface protective layer on the Zn anode has been fabricated by a convenient and straightforward replacement reaction of Bi(CF3SO3)3 with Zn anode in dimethoxyethane (DME) solution at room temperature. The Ar+ etching X‐ray photoelectron spectrometer (XPS) proves that the protective layer is composed of metal Bi, ZnS and ZnSO3, suggesting the success of replacement reaction. This artificial protective layer is propitious to control nucleation sites of Zn2+ and favorable Maxwell‐Wagner polarization, resulting in uniform Zn stripping/plating. In addition, the scanning electron microscope (SEM), Tafel plots and X‐ray diffraction (XRD) demonstrate that the interface layer can effectively suppress side reactions and dendrite growth. Therefore, the symmetric cells with modified Zn anode exhibit superior cycling stability at diverse current densities with a fixed capacity of 1 mAh cm−2 and higher coulombic efficiency (CE) than half‐cells with pristine Zn anode. Simultaneously, modified Zn/NH4V4O10 full‐cells present higher specific capacity, superior cycling stability and rate capability. This simple method provides a new way to modify the Zn anodes for the development of industrialization of aqueous rechargeable ZIBs.

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Dabigatran etexilate

2021

Reactions Weekly

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Dabigatran-induced esophageal injury: a case report

Cited by 3 publications

References 5 publications

Analysis of the clinical characteristics of dabigatran-induced oesophagitis

Analysis of the clinical characteristics of dabigatran-induced oesophagitis

A Simple Route to Fabricate an Artificial Interface Protective Layer on a Zn Anode for Aqueous Zn‐Ion Batteries

Dabigatran etexilate

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