Dairy Fat Consumption and the Risk of Metabolic Syndrome: An Examination of the Saturated Fatty Acids in Dairy

Unger, Allison L; Torres-Gonzalez, Moises; Kraft, Jana

doi:10.3390/nu11092200

Cited by 59 publications

(54 citation statements)

References 119 publications

(209 reference statements)

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“…A systematic review by Telle-Hansen et al (84) of 37 RCT suggests minor or no effects of dietary fat intake on inflammatory markers in overweight/obese subjects. Emerging evidence indicates that dairy product consumption is linked to lower risk for CVD and metabolic syndrome, and the lack of detrimental effects from intake of saturated fat can be attributed to the heterogeneity of saturated fatty acids unique to the dairy food matrix (85). Specifically, a systematic review by Drouin-Chartier et al (34) concluded that neither total dairy product nor cheese consumption was associated with higher risk for coronary artery disease or CVD, and total dairy product and cheese intake were associated with lower stroke risk.…”

Section: Discussionmentioning

confidence: 99%

The Effects of Dairy Product and Dairy Protein Intake on Inflammation: A Systematic Review of the Literature

Nieman

Anderson

Cifelli

2020

Journal of the American College of Nutrition

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Systemic inflammation is associated with obesity and chronic disease risk. Intake of dairy foods is associated with reduced risk of type 2 diabetes and cardiovascular disease; however, the impact of dairy foods on inflammation is not well-established. The objective of this study was to conduct a systematic review to evaluate the effect of dairy product (milk, cheese, and yogurt) and dairy protein consumption on low-grade systemic inflammation in adults without severe inflammatory disorders. A literature search was completed in September 2019 using PubMed and CENTRAL as well as inspection of reference lists from relevant review articles. The search resulted in the identification of 27 randomized controlled trials which were included in this analysis. In the 19 trials which evaluated dairy products, 10 reported no effect of the intervention, while 8 reported a reduction in at least one biomarker of inflammation. All 8 trials that investigated dairy protein intake on markers of inflammation reported no effect of the intervention. The available literature suggests that dairy products and dairy proteins have neutral to beneficial effects on biomarkers of inflammation. Additional clinical studies designed using inflammatory biomarkers as the primary outcome are needed to fully elucidate the effects of dairy intake on inflammation.

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Section: Discussionmentioning

confidence: 99%

The Effects of Dairy Product and Dairy Protein Intake on Inflammation: A Systematic Review of the Literature

Nieman

Anderson

Cifelli

2020

Journal of the American College of Nutrition

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“…Dietary factors, especially hypercaloric diets, are the main contributors to the aetiology of MtS [28]. Chronic consumption of HFD induces overweight along with metabolic and cardiovascular alterations, such as insulin resistance, dyslipidemia or hypertension, among others, being all of these symptoms of the MtS [3,4].…”

Section: Discussionmentioning

confidence: 99%

Beneficial Effect of a Multistrain Synbiotic Prodefen® Plus on the Systemic and Vascular Alterations Associated with Metabolic Syndrome in Rats: The Role of the Neuronal Nitric Oxide Synthase and Protein Kinase A

et al. 2020

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A high fat diet (HFD) intake is crucial for the development and progression of metabolic syndrome (MtS). Increasing evidence links gut dysbiosis with the metabolic and vascular alterations associated with MtS. Here we studied the use of a combination of various probiotic strains together with a prebiotic (synbiotic) in a commercially available Prodefen® Plus. MtS was induced by HFD (45%) in male Wistar rats. Half of the MtS animals received Prodefen® Plus for 4 weeks. At 12 weeks, we observed an increase in body weight, together with the presence of insulin resistance, liver steatosis, hypertriglyceridemia and hypertension in MtS rats. Prodefen® Plus supplementation did not affect the body weight gain but ameliorated all the MtS-related symptoms. Moreover, the hypertension induced by HFD is caused by a diminished both nitric oxide (NO) functional role and release probably due to a diminished neuronal nitric oxide synthase (nNOS) activation by protein kinase A (PKA) pathway. Prodefen® Plus supplementation for 4 weeks recovered the NO function and release and the systolic blood pressure was returned to normotensive values as a result. Overall, supplementation with Prodefen® Plus could be considered an interesting non-pharmacological approach in MtS.

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“…The national dietary guidelines might treat SFA contained in the diet as a single group of nutrients [30].…”

Section: Discussionmentioning

confidence: 99%

Dietary Intake and Hypertension Risk: A Cross-Sectional Survey Using Data from the China hypertension survey, 2012-2015

Yong

et al. 2020

Preprint

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Background: Available data about the effects of dietary intake on hypertension remains limited and conflicting. The purpose of this study was to assess the correlation between dietary intake and the incidence of hypertension. Methods: The China Hypertension Survey was conducted nationwide, and the data of 19,277 residents from Sichuan was organized, and finally 2,010 samples were selected into this study. Standard food frequency questionnaires were used to collect dietary intake data and physical examinations including blood pressure were performed on site. The subjects were classified into hypertensive group (n=356) and non-hypertensive group (n=1,654). The odds ratio (OR) for the occurrence of hypertension according to the quartiles of the dietary intake was evaluated by multivariable logistic regression. Results: After adjustment for all potential confounding variables, more than 50g of daily egg intake was a risk factor for hypertension prevalence (OR=2.11; 95% CI: 1.34-3.32), and 1.94-3.33g of animal oil intake per day was a protective factor (OR=0.57; 95% CI: 0.37-0.88). Conclusions: Our findings demonstrate a significant positive correlation between eggs above 50g and the risk of hypertension, while 1.94-3.33g of animal oil is negatively correlated with the risk of hypertension, indicating that adherence to a small amount of eggs and an appropriate amount of animal oil intake have beneficial effects on the prevention of hypertension.

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Dairy Fat Consumption and the Risk of Metabolic Syndrome: An Examination of the Saturated Fatty Acids in Dairy

Cited by 59 publications

References 119 publications

The Effects of Dairy Product and Dairy Protein Intake on Inflammation: A Systematic Review of the Literature

The Effects of Dairy Product and Dairy Protein Intake on Inflammation: A Systematic Review of the Literature

Beneficial Effect of a Multistrain Synbiotic Prodefen® Plus on the Systemic and Vascular Alterations Associated with Metabolic Syndrome in Rats: The Role of the Neuronal Nitric Oxide Synthase and Protein Kinase A

Dietary Intake and Hypertension Risk: A Cross-Sectional Survey Using Data from the China hypertension survey, 2012-2015

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