Damage control surgery in intracerebral hemorrhage in acute leukemia: a review of two cases

Singh, Jaskaran; Garg, Kanwaljeet; Sharma, Rajeev; Sinha, Sumit; Kale, Shashank Sharad

doi:10.1007/s00381-017-3401-6

Cited by 3 publications

(4 citation statements)

References 11 publications

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“…ICH is a very rare initial presentation of AML; however, it is the second associated leading cause of death in patients with AML [ 8 , 9 ]. The patient had several risk factors contributing to ICH as listed in other studies, which are hypertension, hyperleukocytosis, and thrombocytopenia.…”

Section: Discussionmentioning

confidence: 99%

Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia

Hamadi¹,

Assaad²,

Zurndorfer³

et al. 2022

Cureus

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We present the case of a 73-year-old patient who was admitted to the neurocritical care unit with spontaneous intracerebral hemorrhage (ICH). Upon further investigation, she was found to have hyperleukocytosis and thrombocytopenia due to acute myelogenous leukemia (AML), likely resulting in coagulopathy, vessel friability, and consequential intraparenchymal bleed. Prior reports of AML presenting with ICH are scant in the literature. As such, a heightened awareness of such a phenomenon is recommended for rapid detection and appropriate tailored management. This hopefully would, in turn, optimize outcomes.

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Section: Discussionmentioning

confidence: 99%

Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia

Hamadi¹,

Assaad²,

Zurndorfer³

et al. 2022

Cureus

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“…Case reports from Argentina and Mexico (54, 55) showed use of DC in the management of tumors and patients initially improved post-operatively but complications including death and metastasis were observed in long-term follow-up. Another case report of 2 pediatric patients with ICH in acute leukemia from India (56) showed favorable outcomes following DC.…”

Section: Studies Of DC In Other Pathologiesmentioning

confidence: 99%

The Role of Decompressive Craniectomy in Limited Resource Environments

et al. 2019

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Decompressive craniectomy (DC) is a neurosurgical procedure useful to prevent and manage the impact of high intracranial pressure (ICP) that leads to brain herniation and brain's tissue ischemia. In well-resourced environment this procedure has been proposed as a last tier therapy when ICP is not controlled by medical therapies in the management of different neurosurgical emergencies like traumatic brain injury (TBI), stroke, infectious diseases, hydrocephalus, tumors, etc. The purpose of this narrative review is to discuss the role of DC in areas of low neurosurgical and neurocritical care resources. We performed a literature review with a specific search strategy in web repositories and some local and regional journals from Low and Middle-Income Countries (LMICs). The most common publications include case reports, case series and observational studies describing the benefits of the procedure on different pathologies but with several types of biases due to the absence of robust studies or clinical registries analysis in these kinds of environments.

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“…2 3 The first manifestation of ALL is usually non-specific, 3 and there have been only a few reports of intracerebral haemorrhage (ICH) as an initial presentation of acute leukaemia in adolescents. [4][5][6][7][8][9] To our knowledge, three out of six of those reports involved fatal ICH. Haemorrhage is the second most common cause of mortality in acute leukaemia, and associated risk factors of fatal ICH include leucocytosis, thrombocytopenia and prolonged prothrombin time.…”

Section: Descriptionmentioning

confidence: 99%

“…While T-ALL is a heterogeneous disease with diverse clinical and molecular features, hyperleucocytosis and central nervous system (CNS) involvement are common components of its clinical profile 2 3. The first manifestation of ALL is usually non-specific,3 and there have been only a few reports of intracerebral haemorrhage (ICH) as an initial presentation of acute leukaemia in adolescents 4–9. To our knowledge, three out of six of those reports involved fatal ICH.…”

Section: Descriptionmentioning

confidence: 99%

Intracerebral haemorrhage as an initial manifestation of T-cell acute lymphoblastic leukaemia in a paediatric patient

Crawford

2022

BMJ Case Rep

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Images in…This case adds to the current literature on ICH as a rare initial manifestation of T-ALL in paediatric patients. It demonstrates the neuroimaging characteristics of acute leukaemias presenting with ICH and reveals the role of managing hyperleucocytosis, platelet and coagulation abnormalities in the face of ICH for improved clinical outcomes.Contributors CH was responsible for the design and writing of the case report. YYL was responsible for the design and writing of the case report. JRC was responsible for the design and writing of the case report.

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Damage control surgery in intracerebral hemorrhage in acute leukemia: a review of two cases

Cited by 3 publications

References 11 publications

Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia

Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia

The Role of Decompressive Craniectomy in Limited Resource Environments

Intracerebral haemorrhage as an initial manifestation of T-cell acute lymphoblastic leukaemia in a paediatric patient

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