Das Magenstumpfkarzinom: eine Spätkomplikation des operierten Magens?

Gerstenberg, E; Albrecht, Alexander; Krentz, K; Voth, Harald

doi:10.1055/s-0028-1113498

Cited by 22 publications

(8 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This corresponds with the experience of Pack and Banner (1958) but falls short of the claim made by Lecomte, Monges, Legre, Commandre, Giacobi, and Vedel (1965) who claim an accuracy of 22 out of 23 in personal cases. It is probably reasonable to say with Gerstenberg, Albrecht, Krentz, and Voth (1965) that radiology provides the most convincing evidence of gastric stump carcinoma. Hoffmann (1960) comments upon the numerous problems of practical interest in those patients who have developed cancer of the stomach late after gastric operation.…”

Section: Discussionmentioning

confidence: 99%

Gastric cancer associated with gastroenterostomy and partial gastrectomy.

Pygott¹

1968

Gut

View full text Add to dashboard Cite

Gastric surgery as a definitive method of treatment for simple peptic ulcer has been practised on an increasing scale over the last 50 or 60 years. Despite operation complete relief may not result and the patient may present at widely varying periods afterwards with new or recurrent symptoms. Increasing age brings an increased risk of gastric cancer but the onset of this occasional sequel may be obscured by symptoms which may have followed more immediately after operation. The purpose of this paper is to describe our experiences in the radiological diagnosis of gastric cancer in 13 patients who had already had gastric surgery for simple peptic ulceration, eight having had a gastroenterostomy and five a partial gastrectomy.Records of individual cases of gastric cancer following gastroenterostomy appear in the literature from the mid 1920s onwards. Beatson gastric or duodenal ulcer. Eleven cases of gastric cancer were encountered among the patients previously operated on for duodenal ulcer, an average of 15 years after the gastroenterostomy. There were six cases of gastric cancer among those operated upon for gastric ulcer but five of the gastric ulcer cases were operated upon within two years of gastroenterostomy so it may be that the original diagnosis of simplicity was incorrect. Freedman and Berne (1954) record a collected series of 55 patients with gastric carcinoma of the gastroduodenal stoma and added a further three of their own. In their series 24 primary operations were for duodenal ulcer and 14 were for gastric ulcer, the reason being unknown in the remainder. The average interval between gastroenterostomy and the recognition of gastric cancer in their series was 17 years and in their personal cases the interval was from 26 to 40 years. Helsingen and Hillestad (1956) were able to obtain information about 229 patients who had had a partial gastrectomy for simple peptic ulcer from 10 to 35 years before: 11 cases of cancer of the gastric stump occurred at an interval of 20 years and 10 of these followed resection for gastric ulcer and only one for duodenal ulcer. They comment that the observed rate of carcinoma in gastric ulcer patients is about three times the expected rate and that in duodenal ulcer patients it is approximately the normal rate. De Jode (1961) reported 19 cases of gastric cancer following gastric operations, 12 following gastroenterostomy and seven partial gastrectomy in the 10 years 1949-58 at The London Hospital. Nine of his 12 gastroenterostomies were for duodenal ulcer and so were four of the seven partial gastrectomies; the remaining operations were for gastric ulcer. The interval between operation and gastric cancer was from 18 to 37 years in cases of gastroenterostomy and from two to 36 years after partial gastrectomy. In two cases occurring less than five years following the latter operation one patient had originally a duodenal ulcer and the other a gastric ulcer but in both the carcinoma was at the cardia and remote from the orig-117

show abstract

Section: Discussionmentioning

confidence: 99%

Gastric cancer associated with gastroenterostomy and partial gastrectomy.

Pygott¹

1968

Gut

View full text Add to dashboard Cite

show abstract

“…[9] ptomlosen oder symptomarmen Intervall auftreten, sind daher solange carcinomver-d~ichtig, bis nicht gastroskopisch und histologisch das Gegenteil bewiesen ist. [9] ptomlosen oder symptomarmen Intervall auftreten, sind daher solange carcinomver-d~ichtig, bis nicht gastroskopisch und histologisch das Gegenteil bewiesen ist.…”

Section: Klinik Des Magenstumpfcarcinomsunclassified

“…In den letzten Jahren sind vermehrt Mitteilungen tiber primiire Carcinome im operierten Ulcusmagen erschienen; es herrscht jedoch nach wie vor Unklarheit fiber die Hiiufigkeit ihres Auftretens.Von einem Magencarcinomrezidiv werden die primiiren Carcinome im operierten Magen definitionsgemiiB durch folgende Bedingungen abgegrenzt [9,14]: The risk to develop a carcinoma after resection for peptic ulcer shows a two-to three-fold increase compared to gastric cancer mortality of the normal population.…”

unclassified

See 1 more Smart Citation

Zur Pathogenese und Klinik des Magenstumpfcareinoms

Peitsch

Burkhardt

1976

Langenbecks Arch Chiv

View full text Add to dashboard Cite

Statistics of postmortem examinations and retrospective long-term observations indicate a disposition of the resected stomach for the development of a primary carcinoma. The risk to develop a carcinoma after resection for peptic ulcer shows a two- to three-fold increase compared to gastric cancer mortality of the normal population. Because of the lack of typical symptoms for gastric stump cancer surgical treatment will occur late and the 5-years survival rate is only 1.38%. The cause of the increased cancer risk after gastric resection seems to be the atrophic gastritis in the gastric remnant which is found after a few years.

show abstract

“…Beim Menschen scheinen die Verh/~ltnisse anders zu liegen; Magenstumpfcarcinome nach Gastroduodenostomie geh6ren zu den seltenen Beobachtungen [7,8]. Auf die Analogie im tIinblick auf die Lokalisation wurde bereits hingewiesen.…”

Section: Diskussionunclassified

Experimentelles Anastomosencarcinom

Dahm¹,

Waldenfels²

1973

Langenbecks Arch Chiv

View full text Add to dashboard Cite

Experimental Anastomosing Carcinoma A Contribution to the Pathogenesis of Gastric Carcinoma after Stomach ResectionSummary. 66 male Wistar rats, subjected to gastric resection according to Billroth I or Billroth II and subsequently exposed to Nitrosoguanidine as oral carcinogen, developed carcinomas and precancerous lesions at a rate of 65,1%. The tumours were characterized histologically as adenocarcinomas; they were almost exclusively localized in the region of the gastroduodenal or gastrojcjunal anastomosis. The process of cancer development was completed within 17 to 31 weeks on continous administration of 120 mg/lofNitrosoguanidine in the drinking water. 34 control animals either with intact stomachs subjected to the carcinogen or operated and kept under normal drinking water showed no cancer formation. Only one precancerous lesion (adenomatous hyperplasia) could be observed in the control group with intact stomachs.Trying to relate the present findings to the occurrence of gastric stump carcinoma in man the following conclusions can be made: 1. The operated stomach is predilected for cancer development. 2. Exposure of the operated stomach to an oral carcinogen induces carcinogenesis prevalent in the anastomotic region.

show abstract

Das Magenstumpfkarzinom: eine Spätkomplikation des operierten Magens?

Cited by 22 publications

References 0 publications

Gastric cancer associated with gastroenterostomy and partial gastrectomy.

Gastric cancer associated with gastroenterostomy and partial gastrectomy.

Zur Pathogenese und Klinik des Magenstumpfcareinoms

Experimentelles Anastomosencarcinom

Contact Info

Product

Resources

About