Data Linkage to Explore the Risk of Low Birthweight Associated with Maternal Proximity to Hazardous Waste Sites from the National Priorities List

Wa, Sosniak; We, Kaye; Tm, Gomez

doi:10.1080/00039896.1994.9937475

Cited by 32 publications

(32 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, all 95 percent confidence intervals included values below one. Estimates were slightly higher than, or within range of, results reported in studies with positive results for birth defects (11)(12)(13)(14)(15). This study had a much smaller sample size than these other studies with positive results, and the 95 percent confidence intervals for the largest category, which contained all defects combined, included the fewest values below one.…”

Section: Discussioncontrasting

confidence: 48%

See 1 more Smart Citation

Fetal and neonatal deaths and congenital anomalies associated with open dumpsites in Alaska Native villages

Gilbreath¹,

Kass

2006

International Journal of Circumpolar Health

View full text Add to dashboard Cite

Objective. To determine if women living in Alaska Native villages with open dumpsites ranked as higher hazard have higher rates of adverse pregnancy outcomes than women living in villages with sites that have lower hazard rankings. Adverse pregnancy outcomes examined included fetal and neonatal death and congenital anomalies. Study Design. A population-based retrospective cohort study. Methods. Birth records from 1997-2001 were used to identify the 10 360 eligible infants born to mothers who resided in 197 Alaska Native villages with dumpsite rankings. Exposure variables were derived from hazard rankings of dumpsites. Covariates were obtained from both birth certificate information and village-specific characteristics. Results. Neither crude, nor adjusted estimates detected a statistically significant difference in rates between exposure levels, although adjusted estimates were positive in all congenital anomaly categories, except gastrointestinal defects. Infants born to mothers residing in villages with high hazard dumpsite contents were more likely (RR=4.27; 95% CI: 1.76, 10.36) to have anomalies classified as other defects. Other hazard factors were not significant predictors for any of the adverse outcomes examined. Conclusions. This is the first study to evaluate fetal and neonatal deaths and congenital anomalies associated with open dumpsites in Alaska Native villages. Problems with the study include a population-based exposure measurement, small sample size, and biases related to birth record information. Future studies should include more comprehensive registries of congenital anomalies. (Int J Circumpolar Health 2006;65(2):133-147.)

show abstract

Section: Discussioncontrasting

confidence: 48%

“…Increased risks of adverse pregnancy outcomes have been reported near some individual landfill sites and in multi-site studies (11)(12)(13)(14)(15). However, these studies have never been performed in rural Alaska.…”

Section: Introductionmentioning

confidence: 99%

Fetal and neonatal deaths and congenital anomalies associated with open dumpsites in Alaska Native villages

Gilbreath¹,

Kass

2006

International Journal of Circumpolar Health

View full text Add to dashboard Cite

show abstract

“…Zip codes are of irregular shape, and residence in a zip code near a PCB site is certainly not the optimal indicator of exposure. Previous studies of this type (Shaw et al 1992;Sosniak et al 1994) found that merging a large population database with environmental data is an innovative but not very efficient method of assessing the risks of low birth weight related to the environment. On the other hand, the benefits of such investigations are that they are economical, they may be useful for identifying large risks not previously known, and they may be used as hypothesisgenerating studies (Shaw et al 1992).…”

Section: Discussionmentioning

confidence: 99%

Low birth weight and residential proximity to PCB-contaminated waste sites.

Baibergenova

Kudyakov

Zdeb

et al. 2003

Environ Health Perspect

View full text Add to dashboard Cite

Previous investigations have shown that women exposed to polychlorinated biphenyls (PCBs) are at increased risk of giving birth to an infant with low birth weight (< 2,500 g), and that this relationship is stronger for male than for female infants. We have tested the hypothesis that residents in a zip code that contains a PCB hazardous waste site or abuts a body of water contaminated with PCBs are at increased risk of giving birth to a low-birth-weight baby. We used the birth registry of the New York State Vital Statistics to identify all births between 1994 and 2000 in New York State except for New York City. This registry provides information on the infant, mother, and father together with the zip code of the mother's residence. The 865 state Superfund sites, the 86 National Priority List sites, and the six Areas of Concern in New York were characterized regarding whether or not they contain PCBs as a major contaminant. We identified 187 zip codes containing or abutting PCB-contaminated sites, and these zip codes were the residences of 24.5% of the 945,077 births. The birth weight in the PCB zip codes was on average 21.6 g less than in other zip codes (p < 0.001). Because there are many other risk factors for low birth weight, we have adjusted for these using a logistic regression model for these confounders. After adjusting for sex of the infant, mother's age, race, weight, height, education, income, marital status, and smoking, there was still a statistically significant 6% increased risk of giving birth to a male infant of low birth weight. These observations support the hypothesis that living in a zip code near a PCBcontaminated site poses a risk of exposure and giving birth to an infant of low birth weight.

show abstract

“…The in utero period is one of increased susceptibility to environmental effects, and some studies have suggested that prenatal exposure to environmental toxicants may result in spontaneous abortion, malformations, or low birth weight (Carpenter 1994; Landrigan et al 1999). Results of some other studies, however, have not been consistent with these observations (Baker et al 1988; Croen et al 1997; Fielder et al 2000; Kharrazi et al 1997; Sosniak et al 1994). …”

mentioning

confidence: 68%

Fetal Deaths and Proximity to Hazardous Waste Sites in Washington State

Mueller

Kuehn

Shapiro-Mendoza

et al. 2007

Environ Health Perspect

View full text Add to dashboard Cite

BackgroundThe in utero period is one of increased susceptibility to environmental effects. The effects of prenatal exposure to environmental toxicants on various adverse pregnancy outcomes, including fetal death, are not well understood.ObjectiveWe examined the risk of fetal death in relation to maternal residential proximity to hazardous waste sites.MethodsWe conducted a population-based case–control study using Washington State vital records for 1987–2001. Cases were women with fetal deaths at ≥ 20 weeks (n = 7,054). Ten controls per case were randomly selected from live births. Locations of 939 hazardous waste sites were identified from the Department of Ecology registry. We measured distance from maternal residence at delivery to the nearest hazardous waste site, and calculated odds ratios (ORs) and 95% confidence intervals (CIs).ResultsThe risk of fetal death for women residing ≤ 0.5 miles, relative to > 5 miles, from a hazardous waste site was not increased (adjusted OR = 1.06; 95% CI, 0.90–1.25). No associations were observed for any proximity categories ≤ 5 miles from sites with contaminated air, soil, water, solvents, or metals; however, fetal death risk increased among women residing ≤ 1 mile from pesticide-containing sites (OR = 1.28; 95% CI, 1.13–1.46).ConclusionThese results do not suggest that fetal death is associated with residential proximity to hazardous waste sites overall; however, close proximity to pesticide-containing sites may increase the risk of fetal death.

show abstract

Data Linkage to Explore the Risk of Low Birthweight Associated with Maternal Proximity to Hazardous Waste Sites from the National Priorities List

Cited by 32 publications

References 18 publications

Fetal and neonatal deaths and congenital anomalies associated with open dumpsites in Alaska Native villages

Fetal and neonatal deaths and congenital anomalies associated with open dumpsites in Alaska Native villages

Low birth weight and residential proximity to PCB-contaminated waste sites.

Fetal Deaths and Proximity to Hazardous Waste Sites in Washington State

Contact Info

Product

Resources

About