Data on the distribution of fibre types in five human limb muscles An autopsy study

Jennekens, F. G. I.; Tomlinson, B. E.; Walton, J.N.

doi:10.1016/0022-510x(71)90215-2

Cited by 126 publications

(47 citation statements)

References 12 publications

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“…A number of methods have been employed to describe the spatial distribution in whole fascicles (Jennekens et al, 1971;Lester et al, 1983;Lexell et al, 1983;Paton and Zucker, 1983;Grotmol et al, 1988;Venema, 1988). Another approach has been to divide the fascicle and count the different types of muscle fiber in each layer (Sjøstrøm et al, 1986;Grotmol et al, 1988;Pernus and Erzen, 1991;Strøm and Holm, 1994).…”

Section: Discussionmentioning

confidence: 99%

Spatial distribution of fiber types within skeletal muscle fascicles from Standardbred horses

et al. 2002

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Skeletal muscle fascicles from superficial and deep portions of semitendinosus (ST) and gluteus medius (GM) muscles from Standardbred trotters were analyzed with regard to muscle fiber type proportion (types I, IIA, and IIB) and spatial distribution. Muscle fibers within a fascicle were divided into four layers (L 1-4 ) from the fascicle periphery toward the center. The observed proportions of fiber types among layers were found to be statistically significantly different from a random distribution of fiber types. Type IIB fibers predominated in the peripheral layer, type I fibers prevailed in the layer underneath, and proportions close to the mean of the whole fascicles were observed in the central layer. This pattern of spatial distribution of fiber types within the layers of the fascicles was observed at all four muscle sampling sites. The functional significance of the common pattern is unknown, but possible functional roles are discussed. Anat Rec 268: 131-136, 2002.

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Section: Discussionmentioning

confidence: 99%

Spatial distribution of fiber types within skeletal muscle fascicles from Standardbred horses

et al. 2002

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“…Previous studies have examined the fiber type composition for a subset of upper extremity muscles (Jennekens et al, 1971;Johnson et al, 1973) or for individual upper extremity muscle (Jozsa et al, 1978;Fitts et al, 1989;Klitgaard et al, 1990;Jürimäe et al, 1996;Trappe et al, 2000); in addition, fiber type cross-sectional areas (CSA) have been measured in supraspinatus and deltoid muscles (Gansen and Irlenbusch, 2002). However, a complete set of fiber typing and CSA analysis data for all of the 14 muscles that cross the human glenohumeral joint is unavailable.…”

Section: Introductionmentioning

confidence: 99%

Fiber type composition and maximum shortening velocity of muscles crossing the human shoulder

et al. 2006

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A study of the fiber type composition of fourteen muscles spanning the human glenohumeral joint was carried out with the purpose of determining the contribution of fiber types to overall muscle cross-sectional area (CSA) and to estimate the maximum shortening velocity (V(max)) of those muscles. Muscle biopsies were procured from 4 male cadavers (mean age 50) within 24 hr of death, snap frozen, mounted, and transversely sectioned (10 microm). Slides were stained for myofibrillar ATPase after alkaline preincubation. Photoimages were taken of defined areas (100 fibers) using the Bioquant system, and fiber type and CSA were measured from these images. Staining for mATPase produced three different fiber types: slow-oxidative (SO), fast-oxidative-glycolytic (FOG), and fast-glycolytic (FG). On average, the muscle fiber type composition ranged from 22 to 40% of FG, from 17 to 51% of FOG, and from 23 to 56% of SO. Twelve out of the 14 muscles had average SO proportions ranging from 35 to 50%. V(max) was calculated from the fiber type contribution relative to CSA and shortening velocity values taken from the literature. The maximum velocities of shortening presented here provide a physiological basis for the development of human shoulder musculoskeletal models suitable for predicting muscle forces for functionally relevant tasks encompassing conditions of muscle shortening and lengthening.

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“…This rate, however, is five to eight times slower than that of SR from rabbit white muscle, perhaps because rabbit muscle has uniformly white fibers whereas human muscle shows an approximately even distribution of white and red fibers [18,211. Also, subcellular fractionation of small human muscle biopsies yields preparations of SR that are not as pure or as stable as those from rabbit white muscle.…”

Section: Discussionmentioning

confidence: 94%

Studies of fragmented sarcoplasmic reticulum from human skeletal muscle

Scarpa

DiMauro

Bonilla

et al. 1978

Annals of Neurology

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Sarcoplasmic reticulum (SR) vesicles were isolated from muscle biopsies of 4 normal volunteers, a patient with McArdle disease (before and during contracture), and a patient with normokalemic periodic paralysis. Fractions were analyzed for purity by electron microscopy and biochemical analysis of specific marker enzymes. Adenosine triphosphate (ATP)-dependent calcium ion uptake was measured kinetically by the absorbence changes of murexide, a metallochromic indicator of ionized Ca++ concentrations, in the absence of oxalate or other calcium-complexing anions. In these experiments, time resolution of the Ca++ transport rate was limited by the manual mixing of reagents, which occurred in 1 to 3 seconds. In 1 case the "true" initial velocity of Ca++ uptake was measured by rapid mixing of ATP in a stopped-flow apparatus and by following the change in absorbence of murexide in a storage oscilloscope. In SR from normal human muscle the ATP-dependent Ca++ uptake was 3.5 nmoles per second per milligram of protein for the first 5 seconds after ATP mixing. Fast kinetic experiments showed that Ca++ uptake proceeded linearly for the first 500 msec at a rate of 9 nmoles per second per milligram of protein (at 25 degrees C) and then progressively declined to reach steady-state levels in 40 to 50 seconds. No abnormality of Ca++ transport was found in SR vesicles from the patient with McArdle disease and the patient with normokalemic periodic paralysis.

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Data on the distribution of fibre types in five human limb muscles An autopsy study

Cited by 126 publications

References 12 publications

Spatial distribution of fiber types within skeletal muscle fascicles from Standardbred horses

Spatial distribution of fiber types within skeletal muscle fascicles from Standardbred horses

Fiber type composition and maximum shortening velocity of muscles crossing the human shoulder

Studies of fragmented sarcoplasmic reticulum from human skeletal muscle

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