Data Resource Profile: The Aberdeen Maternity and Neonatal Databank (AMND)

Ayorinde, Abimbola; Wilde, Katie; Lemon, John; Campbell, Doris M.; Bhattacharya, Sohinee

doi:10.1093/ije/dyv356

Cited by 45 publications

(64 citation statements)

References 25 publications

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“…maternity hospital for the geographical area of Aberdeen City, Scotland, U.K. 22 Data is routinely collected continuously from hospital medical records by a dedicated data management team and entered into the AMND database at the end of each pregnancy. 22 All pregnancy records are automatically included and information entered routinely for all women under the jurisdiction of Aberdeen Maternity Hospital.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

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Inherited predisposition to stillbirth: an intergenerational analysis of 26,788 mother-daughter pairs

Woolner

Raja

Bhattacharya

et al. 2019

American Journal of Obstetrics and Gynecology

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Section: Accepted Manuscriptmentioning

confidence: 99%

“…The AMND provides a rare opportunity to study an intergenerational population with a low outmigration rate, 22 enabling us to explore stillbirth in mother-daughter pairs. This cohort has been successfully used in the past to answer a similar question about inherited predisposition to preterm birth.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Inherited predisposition to stillbirth: an intergenerational analysis of 26,788 mother-daughter pairs

Woolner

Raja

Bhattacharya

et al. 2019

American Journal of Obstetrics and Gynecology

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“…16 With theories about the propagation of obesity across generations as the subject of influential commentaries 3 and the evolution of associated theories, the epidemiological literature on the transgenerational influence of pregnancy-related exposures on weight-related outcomes in humans is growing. Several birth cohorts either currently have grandparental, parental, and offspring data [17][18][19][20][21][22][23] or are being extended to include three generations of data. [24][25][26] Many of these cohorts contain only birth data for the offspring and cross-sectional data collected by self-report for the mothers and grandparents at the time of birth of the offspring.…”

Section: Backg Rou N Dmentioning

confidence: 99%

The 3G Multigenerational Cohort of Nova Scotian women and their mothers and offspring

Brown

Woolcott

Dodds

et al. 2020

Paediatric Perinatal Epid

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Background The negative impact of exposures such as maternal obesity, excessive gestational weight gain, and hypertension in pregnancy on the health of the next generation has been well studied. Evidence from animal studies suggests that the effects of in utero exposures may persist into the second generation, but the epidemiological literature on the influence of pregnancy‐related exposures across three generations in humans is sparse. Objectives This cohort was established to investigate associations between antenatal and perinatal exposures and health outcomes in women and their offspring. Population The cohort includes women who were born and subsequently had their own pregnancies in the Canadian province of Nova Scotia from 1980 onward. Design Intergenerational linkage of data in the Nova Scotia Atlee Perinatal Database was used to establish a population‐based dynamic retrospective cohort. Methods The cohort has prospectively collected information on sociodemographics, maternal health and health behaviours, pregnancy health and complications, and obstetrical and neonatal outcomes for two generations of women and their offspring. Preliminary results As of October 2018, the 3G cohort included 14 978 grandmothers (born 1939‐1986), 16 766 mothers or cohort women (born 1981‐2003), and 28 638 children (born 1996‐2018). The cohort women were generally younger than Nova Scotian women born after 1980, and as a result, characteristics associated with pregnancy at a younger age were more frequently seen in the cohort women; sampling weights will be created to account for this design effect. The cohort will be updated annually to capture future deliveries to women who are already in the cohort and women who become eligible for inclusion when they deliver their first child. Conclusions The 3G Multigenerational Cohort is a population‐based cohort of women and their mothers and offspring, spanning a time period of 38 years, and provides the opportunity to study inter‐ and transgenerational associations across the maternal line.

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“…98% of GS participants gave informed consent for data linkage to routinely collected health data and to information from other Scottish population cohort studies, both current and historical. These include several with neonatal and maternity information: the Aberdeen Children of the 1950s ( [23], ACONF); the Aberdeen Maternity and Neonatal Databank ( [24], AMND); the Walker Birth Cohort [25]; and the Scottish Morbidity Records ( [26], SMR02 -the Maternity Inpatient and Day Case record, and SMR11 -the Neonatal Inpatient dataset). Birth weight in grams, alongside gestational age at birth and twin information, was collated from these sources and linked to adult GS records for 4,713 participants (Supplementary File 1).…”

Section: Generation Scotland and Other Cohortsmentioning

confidence: 99%

Birth weight associations with psychiatric and physical health, cognitive function, and DNA methylation differences in an adult population

Madden

McCartney

Martin

et al. 2019

Preprint

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Data Resource Profile: The Aberdeen Maternity and Neonatal Databank (AMND)

Cited by 45 publications

References 25 publications

Inherited predisposition to stillbirth: an intergenerational analysis of 26,788 mother-daughter pairs

Inherited predisposition to stillbirth: an intergenerational analysis of 26,788 mother-daughter pairs

The 3G Multigenerational Cohort of Nova Scotian women and their mothers and offspring

Birth weight associations with psychiatric and physical health, cognitive function, and DNA methylation differences in an adult population

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