2022
DOI: 10.1016/j.dib.2021.107774
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Dataset of Phytochemical and secondary metabolite profiling of holy basil leaf (Ocimum sanctum Linn) ethanolic extract using spectrophotometry, thin layer chromatography, Fourier transform infrared spectroscopy, and nuclear magnetic resonance

Abstract: Holy basil ( Ocimum sanctum Linn) or known also as “kemangi” in Indonesia is a plant commonly used as a herb in Asian countries. It is also medicinal with antipyretic, anti-inflammatory, anti-cancer, and neuroprotective properties. This dataset article provides broad screening of the phytochemical component of Ocimum sanctum ethanolic extract (EEOS) as well as a secondary metabolite profile of EEOS. Analyses were done qualitatively and quantitatively using a combin… Show more

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Cited by 19 publications
(14 citation statements)
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“…Hal ini menunjukkan efek antioksidan Ocimum sanctum yang memiliki peran penting dalam perkembangan penyakit kanker paru. Isothymusin, Cirsimaritin dan eugenol pada Ocimum sanctum terbukti memiliki aktivitas anti kanker paru (Kustiati et al, 2022;Pathak et al, 2020;Singh et al, 2020;Venuprasad et al, 2017). Konsentrasi rendah eugenol hingga 1000 μM ditemukan menurunkan aktivitas siklooksigenase-2, promosi arrest siklus sel pada fase S dan menginisiasi apoptosis pada sel kanker paru.…”
Section: Resultsunclassified
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“…Hal ini menunjukkan efek antioksidan Ocimum sanctum yang memiliki peran penting dalam perkembangan penyakit kanker paru. Isothymusin, Cirsimaritin dan eugenol pada Ocimum sanctum terbukti memiliki aktivitas anti kanker paru (Kustiati et al, 2022;Pathak et al, 2020;Singh et al, 2020;Venuprasad et al, 2017). Konsentrasi rendah eugenol hingga 1000 μM ditemukan menurunkan aktivitas siklooksigenase-2, promosi arrest siklus sel pada fase S dan menginisiasi apoptosis pada sel kanker paru.…”
Section: Resultsunclassified
“…merupakan tanaman tropis yang tumbuh sebagai gulma, dibudidayakan dan seringkali terkait dengan ibadah oleh umat Hindu yang menjadikan tanaman ini simbol penting bagi agama Hindu (Buddhadev et al, 2014). Tanaman kemangi merupakan tanaman yang umum ditemukan pada benua Asia khususnya daerah Asia Tenggara dan Asia Selatan, termasuk Indonesia (Kustiati et al, 2022).…”
Section: Basil (Ocimum Sanctum Linn) Leaf Extractunclassified
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“…In addition, other bioactive compounds in basil leaf extract such as saponin, steroids and terpenoids. Secondary metabolites are also found and classified into metabolite groups including alcohol, amine, carboxylic acid, alkane, alkene, aldehyde, phenol, ether, sulfur, halogen, benzene, nitrogen, sterol, amino acid, carbohydrate and nitrogen 14 .…”
Section: Discussionmentioning
confidence: 99%
“…A wide variety of active phytochemicals, such as flavonoids, phenols, terpenoids, saponins, alkaloids, steroids, and tannins have been identified in EEOS. 25 EEOS phytochemical compounds can act as antiproliferative and apoptotic agents in NSCLC cells by in silico molecular docking and in vitro experiments with different mechanisms of action. 26 Studies showed that the phytochemicals, quercetin, and genistein (flavonoid members), epigallocatechin-3-gallate (phenol members), and sulforaphane induce NO production, alter the redox environment, and thereby facilitate apoptosis.…”
Section: Ligandsmentioning
confidence: 99%