Dataset on the toxic effects of aflatoxin and ochratoxin a on the human gastric smooth muscle cells

Omotayo, Oluwadara Pelumi; Omotayo, Abiodun Olusola; Babalola, Olubukola Oluranti; Mwanza, Mulunda

doi:10.1016/j.dib.2019.104089

Cited by 3 publications

(2 citation statements)

References 3 publications

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“…In southern Africa, maize and its derivatives are a major source of food (Du Plessis, 2003), constituting a significant part of infants' diets. The consumption of contaminated maize and its end products, therefore, affects the health of not only adults but also infants, leading to various complications (Omotayo et al, 2016;Gai et al, 2018;Omotayo et al, 2019b) and in severe cases, death.…”

Section: Disease Outbreak and Health Complicationsmentioning

confidence: 99%

Fusarium verticillioides of maize plant: Potentials of propitious phytomicrobiome as biocontrol agents

Omotayo

Babalola

2023

Front. Fungal Biol.

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Disease outbreaks have been recorded due to exposure to Fusarium verticillioides and fumonisin, a mycotoxin produced by this fungus. F. verticillioides is a fungal pathogen of maize that causes infections, such as wilting and rotting, while contact with its fumonisin derivative manifests in the form of mild to severe illnesses in humans and animals. Maize infection by F. verticillioides causes loss or reduction in expected crop yield, thereby influencing households and nations’ economies. While several efforts have been made to control the pathogenic fungus and its occurrence in the environment, it remains a challenge in agriculture, particularly in maize production. Several microorganisms which are plant-associated, especially those associated with the rhizosphere niche have been noted to possess antagonistic effects against F. verticillioides. They can inhibit the pathogen and tackle its debilitating effects on plants. Hence this study reviews the use of rhizosphere-associated biocontrol agents, such as Bacillus spp., Pseudomonas, Enterobacter, and Microbacterium oleivorans which forms part of the phytomicrobiome in other to prevent and control this toxicogenic fungus. These microorganisms were found to not only be effective in controlling its occurrence on maize plants but are environmentally safe and promote crop yield.

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Section: Disease Outbreak and Health Complicationsmentioning

confidence: 99%

Fusarium verticillioides of maize plant: Potentials of propitious phytomicrobiome as biocontrol agents

Omotayo

Babalola

2023

Front. Fungal Biol.

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“…With acute or chronic intoxication, teratogenic, mutagenic, carcinogenic, immunotoxic, or hepatotoxic effects of aflatoxins were well documented and discussed, especially for dairy cattle and poultry (Mckean et al, 2006;Klingelhofer et al, 2018;Sirma et al, 2018). Recently, toxic effects of aflatoxins on human astrocytes and human gastric smooth muscle cells were investigated (Omotayo et al, 2019;Park et al, 2019 a).…”

Section: Introductionmentioning

confidence: 99%

Occurrence of Aflatoxin B1 in Animal Feed Collected from the Northeastern Area of Morocco

Alahlah¹,

Maadoudi²,

Bouchriti³

et al. 2021

WVJ

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The carry-over of contaminants from feed to animal products is an important issue in the animal production chain, therefore, the quality control of those animal products should include the control of the animal feed. The current study was carried out to assess the contamination levels of three types of animal feed (dairy animal feed, poultry feed, and fish feed) by Aflatoxin B1. A total of 68 animal feed samples were collected from the Northeastern Moroccan area (Tangier-Tétouan-AL Hoceima). The samples were extracted with a mixture of acetone/water. The sample extractions were filtered, diluted with phosphate-buffered saline, and applied to an immunoaffinity column. Aflatoxin B1 was eluted with methanol then analyzed by high-performance liquid chromatography with fluorescence detection, after post-column photochemical derivatization. The analytical results for the level of Aflatoxin B1 in the animal feed samples revealed an average presence of 44.12% for all analyzed samples. The concentrations were between 1.02 and 13.59 µg/Kg, with a mean value of 4.08 ± 3.11 µg/Kg. The results indicated that there was a significant difference across the three types of animal feeds regarding the concentrations of Aflatoxin B1.

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Underreported Human Exposure to Mycotoxins: The Case of South Africa

Nji

Babalola

Nleya

et al. 2022

Foods

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South Africa (SA) is a leading exporter of maize in Africa. The commercial maize farming sector contributes to about 85% of the overall maize produced. More than 33% of South Africa’s population live in rural settlements, and their livelihoods depend entirely on subsistence farming. The subsistence farming system promotes fungal growth and mycotoxin production. This review aims to investigate the exposure levels of the rural population of South Africa to dietary mycotoxins contrary to several reports issued concerning the safety of South African maize. A systematic search was conducted using Google Scholar. Maize is a staple food in South Africa and consumption rates in rural and urban communities are different, for instance, intake may be 1–2 kg/person/day and 400 g/person/day, respectively. Commercial and subsistence maize farming techniques are different. There exist differences influencing the composition of mycotoxins in food commodities from both sectors. Depending on the levels of contamination, dietary exposure of South Africans to mycotoxins is evident in the high levels of fumonisins (FBs) that have been detected in SA home-grown maize. Other potential sources of exposure to mycotoxins, such as carryover effects from animal products and processed foods, were reviewed. The combined effects between FBs and aflatoxins (AFs) have been reported in humans/animals and should not be ignored, as sporadic breakouts of aflatoxicosis have been reported in South Africa. These reports are not a true representation of the entire country as reports from the subsistence-farming rural communities show high incidence of maize contaminated with both AFs and FBs. While commercial farmers and exporters have all the resources needed to perform laboratory analyses of maize products, the greater challenge in combatting mycotoxin exposure is encountered in rural communities with predominantly subsistence farming systems, where conventional food surveillance is lacking.

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Dataset on the toxic effects of aflatoxin and ochratoxin a on the human gastric smooth muscle cells

Cited by 3 publications

References 3 publications

Fusarium verticillioides of maize plant: Potentials of propitious phytomicrobiome as biocontrol agents

Fusarium verticillioides of maize plant: Potentials of propitious phytomicrobiome as biocontrol agents

Occurrence of Aflatoxin B1 in Animal Feed Collected from the Northeastern Area of Morocco

Underreported Human Exposure to Mycotoxins: The Case of South Africa

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