Key points:Solar activity in a two week period starting from 25 February 2015 altered the conditions in the Martian ionosphere.The solar wind conditions and nightside ionosphere of Mars are studied simultaneously, with MAVEN, MEX and Mars Odyssey.High ion escape rates and enhanced densities are observed during SEP enhancements and ICME. Atmosphere and Volatile Evolution Mission (MAVEN), and Mars Odyssey (MO). The ICME disturbances were characterized by an increase in ion speed, plasma temperature, magnetic field magnitude, and energetic electron flux. Furthermore, increased solar wind density and speeds, unusually high local electron densities and high flow velocities were detected on the nightside at high altitudes during the March 8 th event. These effects are thought to be due to the transport of ionospheric plasma away from Mars. The peak electron density at periapsis shows a substantial increase, reaching number densities about 2.7 x 10 4 cm -3 during the second ICME in the deep nightside, which corresponds to an increase in the MOHigh-Energy Neutron Detector flux, suggesting an increase in the ionization of the neutral atmosphere due to the high intensity of charged particles. SEPs show a substantial enhancement before the shock of fourth ICME causing impact ionization and absorption of the surface echo intensity which drops to the noise levels. Moreover, the peak ionospheric density exhibits a discrete enhancement over a period of about 30 hrs around the same location, which maybe due to impact ionization. Ion escape rates at this time are calculated to be in the order of 10 25 -10 26 s -1 , consistent with MAVEN results, but somewhat higher.