Caffeine, nicotine, and alcohol use by persons with a severe mental illness occurs frequently but is poorly understood. We used qualitative methods to elicit information regarding the functional relationships between legal substance use and its antecedents and consequences. This report summarizes responses provided by 37 psychiatric outpatients who participated in focus groups and key informant interviews regarding the use and functions of alcohol, caffeine, and nicotine. We describe major themes regarding positive and negative consequences, triggers for use, change efforts, and offer observations regarding substance use in this under-served population.
Licit Substance Use Among Psychiatric Outpatients: A Qualitative AnalysisCaffeine, nicotine, and alcohol are used extensively by persons with severe mental illnesses (SMI), often at rates that far exceed rates found in the general population. Test, Wallisch, Allness, and Ripp (1989) reported that 86% of their patients with schizophrenia drank coffee, averaging 6 cups per day; this quantity has been associated with caffeine withdrawal and related disorders (American Psychiatric Association, 1994). In contrast, only 9% of the general population consumes as much caffeine (Greden, Fontaine, Lubetsky, & Chamberlain, 1978). Excessive caffeine use can have deleterious effects on mental status, increasing anxiety and depression (Greden et al., 1978;Winstead, 1976), and exacerbating psychotic symptoms in persons with schizophrenia (Carey & Carey, 1989;Mikkelsen, 1978).As many as three-quarters of patients with schizophrenia smoke (Goff, Henderson, & Amico, 1992;Ziedonis, Kosten, Glazer, & Frances, 1994) compared to one-quarter of the general population. In addition to the established risks for cancer and heart disease, additional deleterious effects may accrue for smokers receiving psychiatric treatment. Cigarette smoking increases hepatic enzyme action, hastening the elimination of drugs that depend on hepatic metabolism, thereby reducing plasma concentration of some therapeutic drugs (Perry, Miller, Arndt, Smith, & Holman, 1993). Persons with schizophrenia who smoke have also received higher ratings of positive symptoms (Goff et al., 1992;Ziedonis et al., 1994). Although cause and effect relationships are not clear, nicotine may exacerbate psychotic symptoms and reduce the effectiveness of antipsychotic medications.Alcohol use by the SMI is also common. Among persons diagnosed with schizophrenia, onethird meet criteria for an alcohol use disorder, representing an odds ratio of 3.3. Similar odds ratios for alcohol use disorder range from 1.9 among persons with mood disorders (22%) to 1.5 for persons with anxiety disorders (18%; Mueser, Bellack, & Blanchard, 1992 Drake, Osher, & Wallach, 1989), exacerbation of delusions and hallucinations (Noordsy et al., 1991) and depressive symptoms (Cuffel & Chase, 1994). Larger studies have also confirmed that comorbid alcohol abuse increases the likelihood of violent behavior (Swanson, 1993) among persons with a SMI.Drinking ...