This research was formulated to introduce an electrochemical degradation for the degradation of reactive dyes of the textile industrial wastewater applying a full factorial experimental design. Electrochemical degradation is a green process which immensely reduces the chemical consumption of the wastewater leaving no impurities. Three factors with three-levels were used i.e. the NaCl electrolyte concentrations of 2, 4.5, 5.8 g/L, pH 4.2, 5.8, and 6.9, and reaction time 12.4, 15.5, and 20 min. The experiment was expected to generate 27 runs but due to the Design Expert 12, the number of experimental runs became 20. DC power supply of 14.6 V was used for the electrochemical degradation system whereas chemicals such as nitric acid (400 g/L), sulphuric acid (1.5 mg/L), and oxalic acid solution (100 g/L) were used for surface modification of the electrodes. The textile industrial wastewater was characterized based on the standard method of APHA. Dye, COD, BOD5, and pH of the textile industrial effluent were found to be 0.35 ± 1.00 Abs., 1,711.55 ± 2.00 mg/L, 450.00 ± 3.00 mg/L, and pH of 6.63 ± 0.30, respectively. The maximum color removal was 94.89% at the optimum experimental condition after the results validated by design expert 12. These optimum conditions were the electrolyte concentration 5.1 g/L, pH 6.5, and reaction time 17 min, whereas the minimum color removal of 63.0% was recorded. The regression analysis of the color removal (R2 = 0.95) depicts that electrolyte concentration was the dominant factor for the electrochemical degradation.