Decompressive surgery for treating nerve damage in leprosy

Veen, Natasja H J Van; Schreuders, Ton A.R.; Theuvenet, Willem J.; Agrawal, Amit; Richardus, Jan Hendrik

doi:10.1002/14651858.cd006983.pub3

Cited by 23 publications

(12 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Therefore, in the assessment of chronic pain patients it is important to point out that the Cartesian model does not fit; that is, it is difficult to establish a biological aspect of pain. Unfortunately, medical interventions such as different drugs or surgery would therefore not be expected to have the desired effect [34,35]. We suggest that pain is influenced by different aspects as defined by the neuromatrix theory and should be treated as a multimodal condition [15,36,37].…”

Section: Discussionmentioning

confidence: 92%

Pain and Its Consequences in Quality of Life: A Study with WHOQOL-Bref in Leprosy Patients with Neuropathic Pain

Reis

Gomes

Rodrigues

et al. 2013

ISRN Tropical Medicine

View full text Add to dashboard Cite

Chronic neuropathic pain emerges as a challenge in the treatment of leprosy patients after multidrug therapy discharge. The aim of this study was to determine the quality of life and its repercussions in leprosy patients with chronic pain. We studied male and female patients with chronic neuropathic pain in the last year. Neuropathic pain was confirmed using Douleur Neuropathique en 4 (DN4) and its intensity evaluated by visual analogue scale (VAS). A general questionnaire was applied to evaluate quality of life (WHOQOL-bref). Statistical analyses were composed by descriptive and central tendency. Spearman correlation was used to identify the relation between pain intensity, quality of life domains, and facets. Multiple linear regressions were performed to verify the influence of pain intensity on each facet. Neuropathic pain patients scored worst in physical and environment domains. The low facets were related to pain and discomfort, thinking and concentration, sexual activity, and recreation opportunities. Pain intensity has a high negative influence on psychological domain and recreation opportunities. These findings should contribute to the development of rehabilitation programs considering patients needs to improve their quality of life and true social reintegration.

show abstract

Section: Discussionmentioning

confidence: 92%

Pain and Its Consequences in Quality of Life: A Study with WHOQOL-Bref in Leprosy Patients with Neuropathic Pain

Reis

Gomes

Rodrigues

et al. 2013

ISRN Tropical Medicine

View full text Add to dashboard Cite

show abstract

“…For patients with leprosy, multidrug therapy with rifampicin, clofazimine and dapsone is effective in targeting the M. leprae but not at stopping the inflammatory impairment of nerve function. Neither steroids nor decompressive surgery have been shown to be effective in Cochrane reviews [103,104]. Treatment with thalidomide is also often used -this in itself is associated with a sensory neuropathy and patients must be monitored for future science group this complication clinically if neurophysiological testing is not available [42].…”

Section: Chronic Carementioning

confidence: 99%

Diagnosis and Management of Pediatric Peripheral Neuropathies In Resource-Poor Settings

Wilmshurst

2013

Future Neurol.

View full text Add to dashboard Cite

The diagnosis of a peripheral neuropathy in a child who resides in the majority of resource-poor settings is based on the history taken and the clinical examination. The majority of children, unless they demonstrate additional clinical markers, will lack a more definitive diagnosis beyond the label ‘peripheral neuropathy’. The treatable, typically acquired conditions, which are prevalent in these settings, are the priority to identify. This would include neuroinfections, neuroinflammation, toxins and vitamin deficiencies. The management of children with peripheral neuropathies in resource-poor settings must be approached in a different manner to that of more ‘resource-equipped’ settings. Secondary or tertiary centers are scarce, often significant distances away from the patient, and this leads to long delays before access is possible. Most children present to primary healthcare settings and are seen by practitioners with little training in the features suggestive of a peripheral neuropathy. As such, basic aids to assist the healthcare worker in the early recognition and interventions of a child with a peripheral neuropathy are important. In addition, there must be recognition of the child with a rapidly progressive neuropathy where a life-threatening condition is present, and urgent referral to a tertiary setting made wherever possible.

show abstract

“…For prevention and treatment of the neural damage, the WHO recommends oral corticotherapy and/or a surgical approach for nerve decompression (neurolysis) [6][7][8][9][10] . Until now, the evaluation of postoperative results of the neurolysis was based on pain decrease and sensorimotor function, without considering the person's perception of his/her position in life with regard to the person's culture and his/her system of values and expectations, as proposed by the International Classification of Functioning, Disability and Health (ICF) [9][10][11][12] .…”

Section: Introductionmentioning

confidence: 99%

Avaliação da limitação das atividades diárias e qualidade de vida de pacientes com hanseníase submetidos à cirurgia de neurólise para tratamento das neurites

2013

View full text Add to dashboard Cite

A neurólise é indicada para reduzir o sofrimento neural e impedir a instalação de sequelas e incapacidades em pacientes com hanseníase. O objetivo deste estudo foi verificar o grau de limitação das atividades e a qualidade de vida de pacientes com hanseníase submetidos a neurólise para tratamento das neurites. Participaram do estudo os pacientes submetidos à neurólise no período de 1998 a 2011. Foram coletadas informações sociodemográficas e clínicas, limitações das atividades (SALSA) e a qualidade de vida (WHOQOL-bref). As análises estatísticas incluíram a frequência, as medidas de tendência central e dispersão, os testes de Mann-Whitney e Kruskall-Wallis e o coeficiente de correlação de Spearman adotando-se p<0,05. A amostra foi composta por 36 pacientes com média de idade de 44,0 anos e 3 anos de pós-operatório. Seis pacientes apresentaram grau 0 de incapacidade; 18, grau 1 e 12, grau 2. A principal diferença da escala SALSA ocorreu entre o grau 0 (média 31,8) e o grau 1 (média 42,56). Os valores obtidos na análise do WHOQOL-bref incluíram os domínios físico (média 11,10), psicológico (média 13,41), relações sociais (média 15,15), meio ambiente (média 11,63). As facetas do WHOQOL-bref mais comprometidas foram: capacidade para o trabalho; sentimentos negativos (psicológico); atividade sexual (relações sociais); recursos financeiros (meio ambiente). Apesar da realização da neurólise, a maior parte dos integrantes apresentou limitações nas atividades, sendo maior naqueles com incapacidades físicas. A maior insatisfação na qualidade de vida foi no domínio físico, principalmente no que se refere à dor e à necessidade de cuidados de saúde.

show abstract

Decompressive surgery for treating nerve damage in leprosy

Cited by 23 publications

References 33 publications

Pain and Its Consequences in Quality of Life: A Study with WHOQOL-Bref in Leprosy Patients with Neuropathic Pain

Pain and Its Consequences in Quality of Life: A Study with WHOQOL-Bref in Leprosy Patients with Neuropathic Pain

Diagnosis and Management of Pediatric Peripheral Neuropathies In Resource-Poor Settings

Avaliação da limitação das atividades diárias e qualidade de vida de pacientes com hanseníase submetidos à cirurgia de neurólise para tratamento das neurites

Contact Info

Product

Resources

About