Decrease of urinary taurine in essential hypertension.

Kohashi, Noriyuki; Katori, Ryo

doi:10.1536/ihj.24.91

Cited by 31 publications

(17 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…daily excretion and clearance of T are reported in figure 1 [9], and 57 ±28 [8]. The daily T excretion (mg/day) 106.2±58.0 (controls 98.8 ±49.2) is comparable to that reported in the litera ture: 62.5±28.8 [18], 199=18 [19]. and 211 ±97 [19], In this case a wide dispersion is expected, the reported range is 17.5-331 [4].…”

Section: T Clearancesupporting

confidence: 61%

See 1 more Smart Citation

Is Taurine a Marker for Retinitis pigmentosa ?

Benini

Marconcini²,

Wirth³

et al. 1988

Ophthalmologica

View full text Add to dashboard Cite

In view of contrary reports in the literature on anomalies of taurine concentration in the blood of retinitis pigmentosa patients, taurine clearance has been determined in 19 patients and 17 controls. No significant difference has been found between the average values of the two populations. The taurine content in cataractous crystalline lenses of retinitis pigmentosa patients has been found higher than the taurine content in lenses with senile cataract, but the same behaviour was also shown by five selected proteogenic amino acids. The results are discussed together with related literature data to conclude that taurine can be involved at least in some subtypes of retinitis pigmentosa, but cannot be considered as a marker for the disease.

show abstract

Section: T Clearancesupporting

confidence: 61%

“…The average values of clearance (1/day) 12.9 ±7.7 (controls 12.8 ±8.9) are in the expected range [4], but lower than the report ed value of 15.6 ±1.9 [ 19], All the data for RP patients are no differ ent to those of controls, and only some qual itative differences appear in the distribution of daily T excretion [11],…”

Section: T Clearancementioning

confidence: 99%

Is Taurine a Marker for Retinitis pigmentosa ?

Benini

Marconcini²,

Wirth³

et al. 1988

Ophthalmologica

View full text Add to dashboard Cite

show abstract

“…Moreover, AngII has been also shown to stimulate Ca 2+ cellular transport. 44,45 Taurine may also reduce blood pressure through attenuation of peripheral AngII activity, enhancement of the kinin-kallikrein system in the kidney, 46,47 or decreasing levels of epinephrine and norepinephrine. Additionally, as observed in the current study, taurine supplementation effectively normalizes high blood pressure in the most common animal models of hypertension, including: spontaneously hypertensive rats (SHR), 48 deoxycorticosterone acetate (DOCA)-salt rats, 49 and Dahl-S rats.…”

Section: Discussionmentioning

confidence: 99%

Impact of taurine supplementation on blood pressure in gestational protein-restricted offspring: Effect on the medial solitary tract nucleus cell numbers, angiotensin receptors, and renal sodium handling

Scabora

Lima

Lopes

et al. 2013

J Renin Angiotensin Aldosterone Syst

View full text Add to dashboard Cite

Objective: The current study considers changes of the postnatal brainstem cell number and angiotensin receptors by maternal protein restriction (LP) and LP taurine supplementation (LPT), and its impact on arterial hypertension development in adult life. Methods and results: The brain tissue studies were performed by immunoblotting, immunohistochemistry, and isotropic fractionator analysis. The current study shows that elevated blood pressure associated with decreased fractional urinary sodium excretion (FE Na ) in adult LP offspring was reverted by diet taurine supplementation. Also, that 12-day-old LP pups present a reduction of 21% of brainstem neuron counts, and, immunohistochemistry demonstrates a decreased expression of type 1 angiotensin II receptors (AT 1 R) in the entire medial solitary tract nuclei (nTS) of 16-week-old LP rats compared to age-matched NP and LPT offspring. Conversely, the immunostained type 2 AngII (AT 2 R) receptors in 16-week-old LP nTS were unchanged. Conclusion:The present investigation shows a decreased FE Na that occurs despite unchanged creatinine clearance. It is plausible to hypothesize an association of decreased postnatal nTS cell number, AT 1 R/AT 2 R ratio and FE Na with the higher blood pressure levels found in taurine-deficient progeny (LP) compared with age-matched NP and LPT offspring.

show abstract

“…Milk is known as an important source of dietary taurine for infants (10). Taurine also lowers BP in DOCA-salt hypertensive rats (31) and is antihypertensive in human subjects (32). Further a recent WHO study has found strong, inverse relationships between blood pressure and taurine excretion in 5 Chinese communities (33).…”

Section: Discussionmentioning

confidence: 94%

Altered Electrolyte and Taurine Levels in Milk from Nursing Hypertensive Rats.

1993

View full text Add to dashboard Cite

To examine whether milk factors play a role in the development of hypertension in the spontaneously hypertensive rat (SHR) of the Okamoto strain we have examined the levels of electrolytes and the amino acid taurine in milk from nursing SHR, Wistar Kyoto (WKY) and the stroke prone substrain of the SHR (SHR-SP). The Na+ concentration of SHR milk was significantly higher than that of the WKY and SHR-SP. The K+ concentration of SHR milk tended to be lower than that of WKY and SHR-SP and thus the Na/K ratio of SHR milk was significantly higher than that of both the SHR-SP and WKY. While taurine levels of SHR and SHR-SP milk were 29% and 28% higher than that of WKY respectively, these differences were only of borderline significance (p=0.07). The blood pressure of offspring at 8 and 12 weeks failed to correlate with milk factors within any strain. Thus while the altered levels of electrolytes in milk from SHR may play a role in the development of its hypertension the results for the SHR-SP suggests that these differences are not invariably associated with high blood pressure. (Hypertens Res 1993; 16: 179-184)

show abstract

Decrease of urinary taurine in essential hypertension.

Cited by 31 publications

References 19 publications

Is Taurine a Marker for Retinitis pigmentosa ?

Is Taurine a Marker for Retinitis pigmentosa ?

Impact of taurine supplementation on blood pressure in gestational protein-restricted offspring: Effect on the medial solitary tract nucleus cell numbers, angiotensin receptors, and renal sodium handling

Altered Electrolyte and Taurine Levels in Milk from Nursing Hypertensive Rats.

Contact Info

Product

Resources

About