Decreased second to fourth digit ratios in female multiple sclerosis patients

Gazioğlu, Sibel; Alkan, İsmail; Karaman, Ayse Gul; Boz, Cavit

doi:10.1016/j.earlhumdev.2020.105039

Cited by 3 publications

(2 citation statements)

References 37 publications

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“…Doe et al discovered considerably lower 2D:4D ratios for the right hand in patients with SLE than healthy controls 26 . Also, Gazioglu et al found similar result in patients with multiple sclerosis 27 …”

Section: Discussionmentioning

confidence: 86%

“…Many studies have suggested a link between the 2D:4D ratio and various diseases, including acne vulgaris 20,21 , seborrheic dermatitis 22 , psoriasis 23 , androgenetic alopecia 24 , thyroid disease 25 , lupus erythematosus 26 , multiple sclerosis 27 , ankylosing spondylitis 28 , some psychiatric disorders 29 , and some cancers (such as prostate and bladder) 30,31 . However, to our knowledge, there is not and published research on vitiligo and digit ratio.…”

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confidence: 99%

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Is there a correlation between the second to fourth digit ratio and vitiligo? A cross‐sectional study

Demirbaş

Eker

2022

J of Cosmetic Dermatology

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Vitiligo is a chronic skin disease that manifests itself as completely amelanotic, white, macules, and patches on any part of the body. Selective melanocyte apoptosis may result in irregular, progressive depigmented patches on the skin, mucosal membranes, and hair. Vitiligo is the most common cause of depigmentation on a global scale, with a prevalence of between 0.1% and 2% [1][2][3][4] .Vitiligo is a multifactorial, multigenic disease with complicated pathophysiology, including hereditary and non-genetic causes.Autoimmune, cytotoxic, oxidant-antioxidant, and neurological processes are implicated in melanocyte loss theories 5 . Although segmental and non-segmental vitiligo was formerly assumed to have independent etiologies, it has recently been shown that comparable inflammatory pathways may play a part in developing both forms 6 . Studies on sex hormones that may have a role in neuroendocrinological pathogenesis have been conducted. In their study, Hussein et al. discovered that male patients with adult vitiligo had

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Section: Discussionmentioning

confidence: 86%