Decreases in COVID-19 Cases, Emergency Department Visits, Hospital Admissions, and Deaths Among Older Adults Following the Introduction of COVID-19 Vaccine — United States, September 6, 2020–May 1, 2021

Abstract

vaccine administration data are reported to CDC by multiple entities using immunization information systems, the Vaccine Administration Management System, pharmacy systems, or direct submission of electronic health records. (https:// www.cdc.gov/coronavirus/2019-ncov/vaccines/distributing/about-vaccine-data. html). Persons were considered fully vaccinated if they received the second dose in a 2-dose COVID-19 vaccine series (Pfizer-BioNTech or Moderna) or 1 dose of the single-dose Janssen (Johnson and Johnson) COVID-19 vaccine. admissions with confirmed COVID-19 diagnosis (C),** , † † and COVID-19 deaths (D) § §, ¶ ¶ among adults, by age group, and rate ratio for persons aged ≥65 or ≥70 and 18-49 years -United States,

High Effectiveness of SARS-CoV-2 Vaccines in Reducing COVID-19-Related Deaths in over 75-Year-Olds, Ceará State, Brazil

“…Previous studies have shown that, by May 2021, more than 40,000 deaths had been prevented due to vaccination of the elderly population in Brazil with the Oxford-AstraZeneca and CoronaVac-Sinovac/Butantan vaccines [ 7 ]. Similar findings were found in the US after use of the first dose of Pfizer-BioNTech, particularly in older adults [ 9 ]. A study in Tennessee/USA showed a reduction of more than 95% in mortality in the vaccinated elderly population between December 2020 and March 2021 [ 10 ].…”

Guidance for Implementing COVID-19 Prevention Strategies in the Context of Varying Community Transmission Levels and Vaccination Coverage

“…The widespread availability and administration of COVID-19 vaccines has changed the trajectory of the pandemic in the United States and significantly reduced hospitalization and mortality among vaccinated persons ( 1 ). Increasing the proportion of eligible persons who are vaccinated reduces the risk for substantial or high community-wide transmission, which in turn reduces the risk for the emergence of new variants that could have the potential to overcome vaccine-induced immunity.…”

“…COVID-19 vaccination remains the most effective means to achieve control of the pandemic. In the United States, COVID-19 cases and deaths have markedly declined since their peak in early January 2021, due in part to increased vaccination coverage ( 1 ). However, during June 19–July 23, 2021, COVID-19 cases increased approximately 300% nationally, followed by increases in hospitalizations and deaths, driven by the highly transmissible B.1.617.2 (Delta) variant * of SARS-CoV-2, the virus that causes COVID-19.…”

COVID-19: Evidenced Health Disparity

“…Figure 1 highlights the 7-day average cumulative cases of COVID-19 in five countries: the United States, Canada, Germany, the Netherlands, and Nigeria. Recently, when the distribution of COVID-19 vaccination became more accessible in most communities in the United States, the daily hospitalization cases due to infection and related death decreased significantly [6][7][8][9]. However, overwhelming evidence indicates differences in infection and associated death rates across different populations [2,3].…”