Decreases in Serum Triacylglycerol and Visceral Fat Mediated by Dietary Soybean .BETA.-conglycinin

Abstract

Soy protein isolate (SPI) is known to reduce the risk of heart disease by lowering serum cholesterol and triacylglycerol (TG) levels. Soybean -conglycinin, which is a component of SPI, might be the active ingredient that prevents and/or ameliorates lifestyle-related diseases, such as hyperlipidemia and obesity. This study aimed to determine the efficacy of soybean -conglycinin for lowering the human serum TG level and visceral fat. Randomized double-blind placebo-controlled designs were used to test the effect of dietary -conglycinin, which was taken in the form of candy.

Soy β-Conglycinin (7S Globulin) Reduces Plasma and Liver Cholesterol in Rats Fed Hypercholesterolemic Diet

“…20 Some studies in animals and human subjects have shown a significant HC effect of dietary soybean protein. 1,11,12 In this study, we examined the effects of different doses of bconglycinin in rats that had received HC diet. At the end of the 28-day treatment there were no differences in the animals' growth among groups during the experimental period.…”

Randomized, Double-Blind, Controlled, Comparative Trial of Formula Food Containing Soy Protein vs. Milk Protein in Visceral Fat Obesity - FLAVO Study -

“…12 The soybased formula food in the present trial consisted of 12 g of SP, which contains 1.5-2.0 g of β-conglycinin. The difference in the amounts of β-conglycinin may lead to different results.…”

Effects of Simultaneous Intake of Soybean Protein and Diacylglycerol on Lipid Profiles and Body Fat Accumulation in Rats

“…8,26) Recently, it was reported that -conglycinin contributes at least in part to the TG-lowering effects of SPI. 27) Thus it is thought that SPI has physiological functions that improve both cholesterol and TG levels.…”