Dedifferentiated liposarcoma of the scrotum. Case report and literature review

Salas-Parra, Ruben D; Tavares, Larissa L; Gupta, Ranjan; Silletti, Joseph P.; Shah, Ajay

doi:10.1093/jscr/rjaa342

Cited by 3 publications

(4 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Paratesticular liposarcoma, however, is a very uncommon condition with only less than 200 cases reported in the literature ( 1 – 3 ). Giant paratesticular liposarcoma is an even rarer presentation and was defined as a tumor size greater than 10 cm ( 2 – 4 ). It is a slow-progressing disease and usually affects men between the fifth decade and the seventh decade.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Giant paratesticular dedifferentiated liposarcoma with intraabdominal extension: a case report

et al. 2023

View full text Add to dashboard Cite

Giant paratesticular liposarcoma is a rare presentation of paratesticular tumor. We present a case of the largest paratesticular liposarcoma described to date with a weight of 4,100 g and measuring 460 × 210 × 130 mm. It was initially mistaken as an inguinoscrotal hernia until a contrast-enhanced computed tomography (CECT) scan of the abdomen and pelvis revealed a huge left paratesticular tumor extending from the scrotum to the mid-abdomen. The challenge was to achieve a tumor-free margin orchidectomy due to the poor fat plane of the tumor to the external iliac artery, psoas muscle, descending colon, and anterior abdominal wall. The surgery was started with laparoscopic dissection for the intraabdominal part of tumor from the vital structure, then followed by inguinal radical orchidectomy and inguinal mesh repair. Postoperative histopathological report revealed a paratesticular dedifferentiated liposarcoma with rhabdomyosarcomatous differentiation with clear margin. The patient had good recovery post operation.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Paratesticular liposarcoma is a rare malignant tumor originating from mesoderm. There are less than 200 cases reported in the English literature to date (1)(2)(3), with very few reported cases measuring more than 10 cm and were referred to as giant liposarcoma (2)(3)(4). It mostly occurs in the fifth to seventh decade of life.…”

Section: Introductionmentioning

confidence: 99%

Giant paratesticular dedifferentiated liposarcoma with intraabdominal extension: a case report

et al. 2023

View full text Add to dashboard Cite

show abstract

“…PLSs are mostly seen in adult patient groups aged between 50 and 60 years [8]. Compared to well-differentiated low-grade liposarcomas, dedifferentiated liposarcomas have a more aggressive course and tend to have higher local recurrence rates, potential for distant metastasis, and a higher risk of death [9]. In metastatic cases, lung, bone, abdomen, and paraspinal soft tissue metastases are more common [10].…”

Section: Discussionmentioning

confidence: 99%

“…They manifest as large scrotal mass lesions appearing just below the superficial inguinal ring [7]. Generally, these masses are misdiagnosed as hydrocele, epididymal cyst, inguinal hernia, hematocele or lipoma [9]. On ultrasonography (US), PLSs appear as heterogeneous, solid, hypoechoic lesions with relatively low vascularity, and sometimes liquefaction may accompany if necrosis is present [5,7].…”

Section: Discussionmentioning

confidence: 99%

Well-differentiated and Dedifferentiated Giant Paratesticular Liposarcoma: A Report of Two Cases and a Review of the Literature

Ateş¹,

Kazıcı²,

Şahin³

et al. 2022

Grand J Urol

View full text Add to dashboard Cite

Paratesticular liposarcomas (PLSs) are mostly painless, slow-growing and extremely rare inguinal or scrotal masses. Reports of approximately 270 cases have been published in the literature so far, but only a few of them contain information about giant PLSs exceeding 10 cm in size. Correct diagnosis and treatment is important as PLSs tend to cause local relapses and distant metastases. Here, we aimed to present, and evaluate a dedifferentiated (24 cm), and a well-differentiated (12 cm) giant PLS in the light of the literature data.

show abstract

Dedifferentiated liposarcoma of the spermatic cord: A case report

Joyce¹,

Lauro²,

Hubbard³

et al. 2021

J Case Rep Images Oncology

View full text Add to dashboard Cite

Introduction: Soft tissue sarcomas account for and #60;1% of all adult malignancies with the most commonly reported being liposarcomas, leiomyosarcomas, or rhabdomyosarcomas. Genitourinary tract (GU) sarcomas are considered as an even more rare subtype of soft tissue sarcomas. A patient who presented with a unilateral painless mass initially diagnosed as a high-grade undifferentiated spindle cell neoplasm most consistent with sarcoma by intralesional excisional biopsy found to be a primary undifferentiated spindle cell sarcoma arising from the left-sided spermatic cord. Final diagnosis after radical resection of the mass was dedifferentiated liposarcoma most likely arising from the spermatic cord. After resection of the mass, the patient was diagnosed with a dedifferentiated liposarcoma most likely arising from the spermatic cord. There is sparse literature on this type of spermatic cord sarcoma. The goal of this case report is to summarize the findings that led to this rare diagnosis. Case Report: This is the case of an 81-year-old white male who presented to his primary care physician due to a mass in his left groin. After initial clinical misdiagnosis and mismanagement, the patient underwent incisional biopsy and was diagnosed with a stage IIIB, cT3 N0 M0 primary undifferentiated spindle cell sarcoma of the left-sided spermatic cord, grade 3. Upon radical resection, the final diagnosis was high grade dedifferentiated liposarcoma measuring 8.8 × 5.0 × 4.8 cm. Conclusion: There is currently a paucity of literature on dedifferentiated liposarcomas arising from the spermatic cord. The patient was initially diagnosed with an undifferentiated spindle cell sarcoma thought to have arisen from the spermatic cord, however, upon undergoing radical resection, the final diagnosis was determined to be a high grade dedifferentiated liposarcoma. This case discusses the rare diagnosis of a dedifferentiated liposarcoma most likely arising from the spermatic cord. It is believed that clinicians should consider malignancy in the differential diagnosis of patients presenting with an inguinal mass.

show abstract

Dedifferentiated liposarcoma of the scrotum. Case report and literature review

Cited by 3 publications

References 9 publications

Giant paratesticular dedifferentiated liposarcoma with intraabdominal extension: a case report

Giant paratesticular dedifferentiated liposarcoma with intraabdominal extension: a case report

Well-differentiated and Dedifferentiated Giant Paratesticular Liposarcoma: A Report of Two Cases and a Review of the Literature

Dedifferentiated liposarcoma of the spermatic cord: A case report

Contact Info

Product

Resources

About