Deep gray matter iron measurement in patients with liver cirrhosis using quantitative susceptibility mapping: Relationship with pallidal T₁ hyperintensity

Abstract

3 Technical Efficacy: Stage 3 J. Magn. Reson. Imaging 2018;47:1342-1349.

Distribution of brain iron accrual in adolescence: Evidence from cross‐sectional and longitudinal analysis

“…Thus, despite the nonquantitative nature of raw signal in DTI and fMRI scans as reflecting iron presence, quantitative information could be inferred from them. Recently, iron was detected using T1 hyperintensity signal in the pallidum of patients with liver cirrhosis (Lee et al, ). Although comparison with QSM revealed good agreement, use of the T1 hyperintensity signal may require pathology that causes the hyperintensity, thereby making the iron signal visible but perhaps inadequate for detection of normal developmental effects.…”

Longitudinal assessment of rabbit renal fibrosis induced by unilateral ureteral obstruction using two‐dimensional susceptibility weighted imaging

“…[22][23][24][25] The technique was traditionally performed in the brain using 3D acquisition, which FIGURE 3: SWI fusion maps of left kidneys in rabbits obtained at baseline (1 ) and week 2 (2 ), week4 (3 ), week 6 (4 ), and week 8 (5 ) following UUO. [22][23][24][25] The technique was traditionally performed in the brain using 3D acquisition, which FIGURE 3: SWI fusion maps of left kidneys in rabbits obtained at baseline (1 ) and week 2 (2 ), week4 (3 ), week 6 (4 ), and week 8 (5 ) following UUO.…”

“…SWI combined the magnitude and phase information to provide high sensitivity to susceptibility differences, such as between superparamagnetic materials including iron and surrounding tissues. [22][23][24][25] The technique was traditionally performed in the brain using 3D acquisition, which FIGURE 3: SWI fusion maps of left kidneys in rabbits obtained at baseline (1 ) and week 2 (2 ), week4 (3 ), week 6 (4 ), and week 8 (5 ) following UUO. The maps show the significant changes of SWI signal intensity in the cortex and medulla, and the thickness of renal parenchyma increases at week 2 compared with baseline, since then the r value gradually decreases over time.…”

Paramagnetic Metal Accumulation in the Deep Gray Matter Nuclei Is Associated With Neurodegeneration in Wilson’s Disease

“…Exclusion criteria included severe neurological impairment or severe liver decompensation, history of other neuropsychiatric disorders or liver disease, and hepatic encephalopathy. T1 hyperintensities in the lentiform nucleus of WD patients are associated with portosystemic shunting and hepatic encephalopathy ( Kozic et al, 2003 ), which may affect regional susceptibility duo to manganese accumulation and the evaluation of neurological symptoms ( Lee et al, 2018 ). Therefore, WD patients with T1 hyperintensities in the lentiform nucleus were excluded from the study.…”