Deep Vein Thrombosis in a Queensland Hospital

Williams, O. B.; McCaffrey, John F.; Lau, O. J.

doi:10.1136/bmj.1.5852.517

Cited by 15 publications

(4 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Table 2 compares the incidence of DVT in our study with that in previously reported series. The incidence of DVT in similar groups of patients from the United Kingdom, North America, and Australia ranges from 17 to 35% [1][2][3][10][11][12][13][14]. The 14% incidence in our study is considerably lower and compares with that from the Sudan, Malaysia, and Japan.…”

Section: Discussioncontrasting

confidence: 47%

Incidence of Deep Vein Thrombosis after Major Abdominal Surgery as Observed in Saudi Arabia

Mofti

1990

Ann Saudi Med

View full text Add to dashboard Cite

The reported incidence of postoperative deep vein thrombosis (DVT) ranges from 3 to 47%. We were unable to locate any report in the literature regarding the incidence of DVT in the population of the Arabian peninsula. We therefore studied the incidence of DVT after major abdominal surgery as assessed by 125 I fibrinogen scanning in 103 local patients. DVT developed in 14 patients (13.6%). This is significantly lower than that reported from temperate regions. However, the morbidity rate among the DVT-positive group was high (21%). Our findings suggest that prophylactic measures against DVT should be a mandatory feature of patient care. Arabia. 1990; 10(6): 602-604 Many studies have reported widely differing incidences of postoperative deep vein thrombosis (DVT) [1][2][3][4]. It has been postulated that climatic or racial factors may be important in the genesis of this complication [7,12]. However, no such information has been available for the Gulf area of the Middle East. The present study was therefore undertaken to determine the incidence of DVT in a group of patients, most of Saudi Arabian origin and living in the Arabian Peninsula, and to allow the formulation of a rational policy of prophylaxis against DVT for this region. AB Mofti, Incidence of Deep Vein Thrombosis after Major Abdominal Surgery as Observed in Saudi Patients and MethodsIn a prospective study, all patients over 40 years of age and of Arabian origin undergoing elective major abdominal surgery at King Khalid University Hospital in Riyadh were included in the investigation. Institutional approval and prior consent to the study were obtained. No form of DVT prophylaxis was used. Relevant clinical data for each patient were recorded and included in a detailed inquiry into the known risk factors contributing to the development of DVT.A total of 103 patients were studied. There were 56 females and 47 males, with an overall age range of 40 to 80 years. Sixty-five percent of the patients were in their fifth decade. Seventy-three patients (71%) were Saudi nationals, while the remaining were of Middle Eastern extraction, living in the Gulf or Arabian peninsula.The types of operative procedures reflect the local pattern of abdominal disorders necessitating surgical intervention in our practice. Most disorders involve the hepatobiliary system or the upper alimentary tract. In only six patients (5.8%) was the large bowel the source of the primary pathology (Table 1).

show abstract

Section: Discussioncontrasting

confidence: 47%

Incidence of Deep Vein Thrombosis after Major Abdominal Surgery as Observed in Saudi Arabia

Mofti

1990

Ann Saudi Med

View full text Add to dashboard Cite

show abstract

“…The incidence of thrombosis was 12% in controls and 15% in the heparin group, both very high. The ultrasound method detects occlusive thrombi in the popliteal or more proximal veins, and the 12-15% postoperative incidence of abnormal results reported here is considerably higher than that reported by others who have screened postoperative patients with this method [25,201]. For this reason, there is a strong possibility that false-positive diagnoses were made in both groups, especially since phlebograms were not performed to confirm the diagnosis.…”

Section: Prophylaxis With Low-dose Heparin Given By Subcutaneous Icontrasting

confidence: 56%

Prevention of Venous Thromboembolism

Gallus¹,

Hirsh²

2008

Semin Thromb Hemost

View full text Add to dashboard Cite

“…This could be due to racial differences, but these could not account for the difference in the incidence of venous thrombosis observed between Brisbane and Sydney (Williams et al, 1973). Fibrinolysis is important in the prevention of postoperative venous thrombosis (Mansfield, 1972, Gordon-Smith et al, 1974 and while it may become possible to inhilbit the coagula-tion changes occurring during surgery with betaadrenergic blockade (Britton et al, 1974) it would be important to leave fibrinolysis unaffected if thrombosis is to be prevented.…”

Section: Discussionmentioning

confidence: 91%

Adrenergic, Coagulation, and Fibrinolytic Responses to Heat

Britton¹,

Hawkey²,

Wood³

et al. 1974

BMJ

View full text Add to dashboard Cite

Several explanations have been proposed to explain these divergent results-failure to define the population being studied; differing, possibly incorrect methods of sample collection; failure to obtain truly "normal" subjects for control purposes, etc. To avoid these various criticisms we have studied a group of normal, asymptomatic women who had not been hospitalized and compared the findings with those in three groups of patients, the pattern of whose illness had been carefully defined by long-term follow-up in a specialist urinary infection clinic. To reduce sampling errors and to define the regular carrier state of these women each was studied weekly for five or six weeks. To exclude the possible influence of recent infection (Marsh et al., 1972) or antibiotic treatment or a changing state before subsequent infection (Stamey et al., 1971) all the patients were known to have had no bacteriuria or antibiotics for six weeks before the study and no bacteriuria during or within six weeks of completion of the study.The results show no difference in the introital carriage rate of E. coli between normal subjects and patients referred with a history of previous urinary infection whether they were subsequently shown to be intermittently bacteriuric, symptomatic and abacteriuric, or asymptomatic and abacteriuric. A small difference in periurethral carriage of enterobacteria in general was observed between normal subjects and the patient groups though there was no difference between the patient groups. Thus it does seem that patients with a previous history of urinary infection may have a slight change in the overall periurethral colonization as compared with normal women but that there is no difference in this respect between those who are subsequently intermittently bacteriuric and those who are persistently abacteriuric. Furthermore, though E. coli was the most common cause of bacteriuria in our patients no difference in the periurethral carriage rate was observed between the normal subjects and the three patient groups. There was also no difference in the recovery rate or persistence of particular E. coli serotypes.When these results are compared with other reports it must be noted that slightly differing techniques are used. Thus Stamey et al. (1971) studied clean-catch urethral urine samples (labelled VBJ) and samples from the vaginal vestibule, Bailey et al. (1973) studied swabs from the external urethral meatus (periurethral swabs) and vaginal vestibule, and Cox et al. (Cox, 1966;Cox et al., 1968) obtained urethral specimens using a specially designed instrument. We have previously used the term "introital" swab to define what is more correctly a periurethral swab. We have also previously shown and subsequently confirmed that colony counts of the same organism are obtained in the same proportion of instances from urethral urine (vB,) and periurethral swabs in normal women and patients alike.By dividing patients into "persistent", "intermittent," and "non-") carriers of introital bacteria on the basis of sw...

show abstract

Deep Vein Thrombosis in a Queensland Hospital

Cited by 15 publications

References 9 publications

Incidence of Deep Vein Thrombosis after Major Abdominal Surgery as Observed in Saudi Arabia

Incidence of Deep Vein Thrombosis after Major Abdominal Surgery as Observed in Saudi Arabia

Prevention of Venous Thromboembolism

Adrenergic, Coagulation, and Fibrinolytic Responses to Heat

Contact Info

Product

Resources

About