Deep Venous Thrombosis

Aquila, Anne

doi:10.1097/00005082-200107000-00004

Cited by 25 publications

(14 citation statements)

References 31 publications

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“…Its sequelae include post-thrombotic syndrome and pulmonary embolism, which can result in long-term disability or death [2]. Accurate detection of thrombosis and assessment of its size and distribution are critical for treatment decision-making [3–6].…”

Section: Introductionmentioning

confidence: 99%

Black-blood thrombus imaging (BTI): a contrast-free cardiovascular magnetic resonance approach for the diagnosis of non-acute deep vein thrombosis

Xie

Chen

et al. 2016

Journal of Cardiovascular Magnetic Resonance

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BackgroundDeep vein thrombosis (DVT) is a common but elusive illness that can result in long-term disability or death. Accurate detection of thrombosis and assessment of its size and distribution are critical for treatment decision-making. In the present study, we sought to develop and evaluate a cardiovascular magnetic resonance (CMR) black-blood thrombus imaging (BTI) technique, based on delay alternating with nutation for tailored excitation black-blood preparation and variable flip angle turbo-spin-echo readout, for the diagnosis of non-acute DVT.MethodsThis prospective study was approved by institutional review board and informed consent obtained from all subjects. BTI was first conducted in 11 healthy subjects for parameter optimization and then conducted in 18 non-acute DVT patients to evaluate its diagnostic performance. Two clinically used CMR techniques, contrast-enhanced CMR venography (CE-MRV) and three dimensional magnetization prepared rapid acquisition gradient echo (MPRAGE), were also conducted in all patients for comparison. All images obtained from patients were analyzed on a per-segment basis. Using the consensus diagnosis of CE-MRV as the reference, the sensitivity (SE), specificity (SP), positive and negative predictive values (PPV and NPV), and accuracy (ACC) of BTI and MPRAGE as well as their diagnostic agreement with CE-MRV were calculated. Besides, diagnostic confidence and interreader diagnostic agreement were evaluated for all three techniques.ResultsBTI with optimized parameters effectively nulled the venous blood flow signal and allowed directly visualizing the thrombus within the black-blood lumen. Higher SE (90.4% vs 67.6%), SP (99.0% vs. 97.4%), PPV (95.4% vs. 85.6%), NPV (97.8% vs 92.9%) and ACC (97.4% vs. 91.8%) were obtained by BTI in comparison with MPRAGE. Good diagnostic confidence and excellent diagnostic and interreader agreements were achieved by BTI, which were superior to MPRAGE on detecting the chronic thrombus.ConclusionBTI allows direct visualization of non-acute DVT within the dark venous lumen and has the potential to be a reliable diagnostic tool without the use of contrast medium.

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Section: Introductionmentioning

confidence: 99%

Black-blood thrombus imaging (BTI): a contrast-free cardiovascular magnetic resonance approach for the diagnosis of non-acute deep vein thrombosis

Xie

Chen

et al. 2016

Journal of Cardiovascular Magnetic Resonance

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“…Although DVTs and PEs are often silent and difficult to detect by clinical examination, they rarely occur in the absence of risk factors. 5 This knowledge can improve clinical prediction considerably. 12 Thrombosis can occur anywhere in the circulatory system.…”

Section: Pathophysiologymentioning

confidence: 99%

“…2 The most serious complication of a DVT is pulmonary embolism (PE), which is associated with 50,000 to 200,000 deaths each year. 5 Other studies have found PE to carry a 10% fatality rate. 3 Another major complication of acute DVT is the long-term socioeconomic consequences of postthrombotic syndrome.…”

mentioning

confidence: 95%

A Patient with Deep Vein Thrombosis Presenting to a Chiropractic Clinic: A Case Report

Fernandez¹,

Pollard²,

McHardy³

2007

Journal of Manipulative and Physiological Therapeutics

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“…2 The progress of a developing DVT is comparatively obscure clinically and without specificity. DVTs at autopsy were found to be the cause of death in 72% of those who died with various diseases.…”

Section: Introductionmentioning

confidence: 99%

Infrared thermal imaging and Doppler vessel pressurization ultrasonography to detect lower extremity deep vein thrombosis: Diagnostic accuracy study

Deng

Tang

Jiang

et al. 2017

Clinical Respiratory J

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Deep Venous Thrombosis

Cited by 25 publications

References 31 publications

Black-blood thrombus imaging (BTI): a contrast-free cardiovascular magnetic resonance approach for the diagnosis of non-acute deep vein thrombosis

Black-blood thrombus imaging (BTI): a contrast-free cardiovascular magnetic resonance approach for the diagnosis of non-acute deep vein thrombosis

A Patient with Deep Vein Thrombosis Presenting to a Chiropractic Clinic: A Case Report

Infrared thermal imaging and Doppler vessel pressurization ultrasonography to detect lower extremity deep vein thrombosis: Diagnostic accuracy study

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