Deep Venous Thrombosis and a Very Rare Finding: Inferior Vena Cava Infra-renal Segment Agenesis

Leitão, Alexandra; Esteves, Joana; Abreu, Jorge Fuentes; Pereira, Alamanda Kfoury; Boncoraglio, Maria Teresa; Certo, M; Ferreira, Rodolfo Abreu

doi:10.12890/2019_001063

Cited by 8 publications

(7 citation statements)

References 3 publications

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“…Aneurysms involving the IVC have been reported in instances of a congenitally absent IVC, but to our knowledge, this congenital anomaly has not been associated with aneurysmal dilation of the RV. Moreover, an absent IVC or aneurysmal IVC typically is manifested with thromboembolic events involving lower extremity swelling and deep venous thrombosis, which was not the case in our patient 5, 7, 8, 9. We presume the congenitally absent segment of our patient's IVC predisposed him to aneurysmal dilation and ultimately the extensive collateralization through the lumbar, azygos, and gonadal veins seen on CT and venography.…”

Section: Discussionmentioning

confidence: 58%

Giant renal vein aneurysm

Madden

Calligaro

Troutman

et al. 2019

Journal of Vascular Surgery Cases, Innovations and Techniques

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A 37-year-old asymptomatic man presented with incidentally identified intra-abdominal venous aneurysms. Workup, which included venography, demonstrated an absent segment of the inferior vena cava between the inferior right and superior left renal vein, resulting in a 4.4-cm right renal vein aneurysm, dilated common iliac veins, and left external iliac vein aneurysm. Collateralization was robust. Given the limited natural history data and complexities of open reconstruction, we opted to observe this asymptomatic patient with serial imaging, which demonstrated no interval change. We present our case and a review of the literature pertaining to intra-abdominal venous aneurysms.

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Section: Discussionmentioning

confidence: 58%

Giant renal vein aneurysm

Madden

Calligaro

Troutman

et al. 2019

Journal of Vascular Surgery Cases, Innovations and Techniques

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“…Therefore, it is crucial to actively investigate the presence of IVCA in this population, particularly in cases of bilateral thrombosis. 10 The increased risk of thrombosis is likely attributed to venous stasis caused by insufficient venous return. 11 These patients are prone to developing bilateral DVT, which is in stark contrast to the reported incidence of less than 10% in patients with DVT and a normal IVC.…”

Section: Discussionmentioning

confidence: 99%

Direct Oral Anticoagulants for Inferior Vena Cava Agenesis

Iarossi,

Hermans

2023

Clin Appl Thromb Hemost

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Deep vein thrombosis (DVT) is common in the general population, with an annual incidence of 1 to 2 per 1000 people. Inferior vena cava agenesis (IVCA) increased the risk of developing DVT and is found in approximately 5% of young adults (20-40-year-olds) diagnosed with unprovoked proximal DVT. IVCA can be caused by a defective embryological process, or be a result of intrauterine or perinatal thrombosis. Its estimated incidence in the general population ranges from 0.0005% to 1%, usually involving a partial absence of one of the four segments of the inferior vena cava (IVC). The management during the extended phase of patients with DVT associated with IVCA is not yet harmonized, as it is poorly described in the literature. Patients with IVCA are considered to be at high risk of DVT occurrence, prompting physicians to continue extended anticoagulation, often using vitamin K antagonists. In this retrospective study, we present a cohort of 11 patients diagnosed with IVCA following a DVT, who subsequently received extended treatment with a direct oral anticoagulants. These findings offer reassuring insights into the extended utilization of direct oral anticoagulants, demonstrating both antithrombotic efficacy and a favorable safety profile.

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“…Як правило, подібна патологія є асимптоматичною за рахунок розгалуженої сітки колатералей і досить часто виявляється під час підготовки до оперативних втручань [12].…”

Section: результати обговоренняunclassified

Features of treatment of venous thromboembolism in patients with abnormalities in the development of the vena cava inferior

Khrebtiy¹

2023

Rep. of Vinnytsia Nation. Med. Univ.

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Annotation. In the treatment of venous thromboembolism, a special place is occupied by patients with congenital anomalies of the development of the inferior vena cava (IVC). To date, only single cases of treatment of this pathology have been described in the literature. Studying the experience of treating patients with congenital anomalies of the IVC will allow to improve the results of treatment of this category of patients. We analyzed the results of treatment of 1243 patients with venous thromboembolism from 2010 to 2022. For the diagnosis of venous thromboembolism, we used duplex scanning of the veins of the lower extremities, phlebography by spiral computed tomography (SCT), angiopulmonography, and phlebography. 32 (2.5%) patients had bilateral thrombosis of the ileofemoral venous segment. Congenital anomalies of IVC development were diagnosed in 2 (0.16%) patients. One patient had IVC aplasia, the other had IVC hypoplasia. Both patients had bilateral ileofemoral phlebothrombosis. For the treatment of patients with congenital anomalies of IVC and bilateral ileofemoral deep vein thrombosis, we used anticoagulant therapy and elastic compression of the lower extremities. During the study period, venous thromboembolic complications in the form of pulmonary embolism were not recorded, fatal complications were not diagnosed. Massive bleeding was not diagnosed in this category of patients during the study period. Thus, the conducted analysis allows us to state that the use of anticoagulant therapy allows to obtain satisfactory results of treatment of patients with congenital abnormalities of the development of the IVC.

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Deep Venous Thrombosis and a Very Rare Finding: Inferior Vena Cava Infra-renal Segment Agenesis

Cited by 8 publications

References 3 publications

Giant renal vein aneurysm

Giant renal vein aneurysm

Direct Oral Anticoagulants for Inferior Vena Cava Agenesis

Features of treatment of venous thromboembolism in patients with abnormalities in the development of the vena cava inferior

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