Definition and causes of infertility

Brugo-Olmedo, Santiago; Chillik, Claudio F.; Kopelman, Susana

doi:10.1016/s1472-6483(10)62187-6

Cited by 77 publications

(41 citation statements)

References 20 publications

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“…Infertility, defined as one year of unprotected coitus without conception, affects approximately 10-15% of couples in the reproductive age group (Brugo-Olmedo et al, 2001), making it an important component of every medical practice. Several changes have taken place in the practice of infertility in the past few decades, including the development of assisted reproductive techniques and increased numbers of women seeking treatment for infertility, many older than 35 years old and often nulliparous.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of low serum cobalamin in infertile couples

et al. 2009

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A high prevalence of low levels of cobalamin had been found in a survey of multi-ethnic normal individuals in Israel. The purpose of this study was to investigate the incidence of cobalamin deficiency among Israeli couples suffering from infertility. All couples seen at the in vitro fertilization clinic at an urban hospital (Shaare Zedek Medical Center) in Jerusalem for a 6-month period were invited. Mean cobalamin levels were 259.2 pg ml(-1) in males and 275.1 pg ml(-1) in females (normal >200 pg ml(-1)), 35.5% of 172 men and 23.3% of 223 females had cobalamin deficiency (P = 0.01). There were 171 couples with complete demographic questionnaires and cobalamin values for each partner. In 74 couples (43.3%), one partner was cobalamin deficient, with no significant difference between those with unexplained infertility versus those with explained infertility; and in 13 couples, both partners were cobalamin deficient. Thirty-nine per cent of all men with an abnormal semen analysis had cobalamin deficiency, a finding that requires further investigation. This study questions whether higher rates of male infertility in Israel are partially ascribable to cobalamin deficiency. Recommendation for supplementation in both males and females to achieve high-normal levels of cobalamin would be prudent.

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Section: Introductionmentioning

confidence: 99%

Prevalence of low serum cobalamin in infertile couples

et al. 2009

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“…Traditionally, demographers have focused on understanding why birth rates are falling and which social and economic factors influence fecundity, but more recently attention has focused on those people who are ''willing but unable'' to have children [17,19,20]. The numbers of infertile couples are not small; some estimates suggest up to one in seven couples can face reduced fecundity at some point in their lives [5,21]. Furthermore, when the increasing numbers of children born from ART every year are positioned within the ageing populations currently affecting many countries it is useful to understand how policy that influences access to ART impacts on total fertility rates [16,18].…”

Section: Introductionmentioning

confidence: 99%

Long-term fiscal implications of subsidizing in-vitro fertilization in Sweden: A lifetime tax perspective

Svensson

Connolly²,

Gallo

et al. 2008

Scand J Public Health

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“…Although both exogenous exposures and endogenous pathological disorders have been associated with infertility, a significant proportion of infertility remains unexplained. In young generation, infertility is now affecting one couple in six [18][19] . This may be due to the decrease in sperm quality as described previously [20] .…”

Section: Discussionmentioning

confidence: 99%

Semen Abnormality And Nigerian Herbal Remedies: A Preliminary Investigation.

2012

IJTO

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The uses of herbal products are not regulated in Nigeria and in many low-income countries and are freely available to everyone. The safety of these herbal medicines is poorly understood. Commonly used herbal remedies can interfere with reproductive health. This is a prospective study that investigated the possible effects of Nigerian herbal remedies on semen quality involving 218 patients who attended the fertility unit of Nnamdi Azikiwe University Teaching Hospital, Nnewi, Southeastern, Nigeria. Questionnaire was administered by an interviewer and a seminal fluid analysis with respect to motility, concentration, and volume were carried using WHO standard. The result showed that 83.97% of the patients with history of herbal intake had abnornal seminal fluid analsis while only 16.03% of subjects with no history of herbal intake had abnormal result.This gives a clue of the possibility of male infertility from Nigerian herbal remedies.The reproductive health damage from consumption of Nigerian herbal remedies should be identified with indepth risk assessment.

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Definition and causes of infertility

Cited by 77 publications

References 20 publications

Prevalence of low serum cobalamin in infertile couples

Prevalence of low serum cobalamin in infertile couples

Long-term fiscal implications of subsidizing in-vitro fertilization in Sweden: A lifetime tax perspective

Semen Abnormality And Nigerian Herbal Remedies: A Preliminary Investigation.

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