Definitions and Epidemiology of Endodontic Infections

Persoon, I.F.; Özok, A.R.

doi:10.1007/s40496-017-0161-z

Cited by 61 publications

(45 citation statements)

References 56 publications

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“…Even though people with diabetes do not necessarily have more caries [12], except possibly if diabetes is poorly controlled [33,35], they experience greater risk of periapical lesions in the jaw bone that seem to be present more often and to be larger in size and take longer to heal compared to normo-glycemic people [38][39][40][41], especially when poorly controlled [42]. The result of untreated caries is eventually the necrosis of the pulp (''nerve") inside the tooth, upon which the various substances from the breakdown of the dead nerves, blood, and connective tissue discharge out through the end of the root of the tooth (apex) and into the surrounding jaw bone and into the systemic blood stream.…”

Section: Periapical Lesionsmentioning

confidence: 99%

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IDF Diabetes Atlas: Diabetes and oral health – A two-way relationship of clinical importance

Borgnakke

2019

Diabetes Research and Clinical Practice

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The current scientific evidence for the bi-directional associations between oral health and diabetes is summarized. The universal biologic mechanisms and demographic and behavioral risk drivers underlying these associations in both directions are also described. Dysglycemia, even slightly elevated blood sugar levels, adversely affects oral health, manifesting itself in several oral diseases and conditions. In the opposite direction, any oral infection with its subsequent local and systemic inflammatory responses adversely affects blood glucose levels. Moreover, painful, mobile, or missing teeth may lead to intake of soft food items representing a sub-optimal diet and hence poor nutrition, and thereby contribute to incident type 2 diabetes or to poorer glucose control in existing diabetes. Treatment of inflammation related oral conditions, such as non-surgical periodontal treatment and extraction of infected teeth, can lead to a clinically significant decrease in blood glucose levels. Attention to infectious oral diseases and referral to dental care professionals for treatment can therefore be an important novel tool for medical care professionals in preventing and managing diabetes mellitus. Dental professionals can detect unrecognized potential dysglycemia and refer for medical examination. Such interprofessional, patient centered care may contribute to improved health, wellbeing, and quality of life in people with diabetes.

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Section: Periapical Lesionsmentioning

confidence: 99%

“…However, there seems to be a void in the scientific literature to specifically support such hypothesis. Nonetheless, the subsequent periapical periodontitis decreases insulin sensitivity [42,78].…”

Section: Cariesmentioning

confidence: 99%

IDF Diabetes Atlas: Diabetes and oral health – A two-way relationship of clinical importance

Borgnakke

2019

Diabetes Research and Clinical Practice

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“…Under normal circumstances, the root canal is a sterile environment and any microorganism that invades this space is regarded as a potential cause of disease. Infection of the pulp can range from easy-to-treat infections such as pulpitis to apical periodontitis [99]. Root canal infections are typically of biofilm aetiology, and the causative microorganisms of endodontitis are also found as commensal organisms in the oral cavity.…”

Section: Endodontic Infections: Sinister Encounters In the Darkmentioning

confidence: 99%

Fungi at the Scene of the Crime: Innocent Bystanders or Accomplices in Oral Infections?

Delaney

Kean

Short

et al. 2018

Curr Clin Micro Rpt

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Purpose of Review Over the last decade, microbiome studies have enhanced our knowledge and understanding of the polymicrobial nature of oral infections. Recently, profiling of the fungal microbiome has expanded our conventional understanding of oral ecology, revealing the critical importance of yeasts within this complex microbiome. This review aims to explore our current appreciation of interkingdom interactions in oral disease. Recent Findings There is a growing evidence base of interactions and pathogenic synergy and antagonism with bacterial species within oral disease. Recent studies have helped to develop our knowledge of how Candida albicans, alongside bacteria such as Porphyromonas gingivalis, Streptococcus mutans, Staphylococcus aureus, Enterococcus faecalis, and Lactobacillus species, influence overall pathogenicity. Summary Clinical and experimental evidence makes a compelling case for a role for C. albicans in a number of oral infections, though whether its role is an active accomplice or passive bystander remains to be determined.

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“…Já nos dentes com tratamentos endodônticos inadequados associados a restaurações coronárias incorretas, a taxa de PA foi de 71,7%. Outros estudos também afirmam que a prevalência de lesão periapical é maior em dentes com tratamento endodôntico de baixa qualidade 17,19,20 .…”

Section: Prevalência De Periodontite Apicalunclassified

Associação entre a periodontite apical e o diabetes mellitus: uma revisão da literatura

Mendes¹,

Teixeira

Michelon³

et al. 2019

Rev. da Fac. de Odontologia, UPF

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Objetivo: O presente trabalho tem por objetivo realizar uma revisão de literatura buscando verificar a relação entre o diabetes mellitus e a periodontite apical (PA). Revisão da Literatura: A PA caracteriza-se por uma perda óssea na região do ápice dental que decorre principalmente da contaminação do sistema de canais radiculares. Embora a PA seja um processo inflamatório local, na região do periápice radicular, sua progressão pode ser influenciada por patologias sistêmicas, como o diabetes. O Diabetes Melittus é uma patologia crônica em que há alteração na produção de insulina ou resistência à ação da mesma, este hormônio auxilia a manter a concentração normal de glicose sanguínea. O quadro de hiperglicemia crônica presente no paciente diabético descompensado ocasiona alterações fisiológicas, que permitem suspeitar de uma relação entre o diabetes e a progressão de lesões periapicais. Considerações finais: A literatura estudada sugere uma associação positiva entre a presença do diabetes e a progressão de lesões periapicais. Porém apesar dos estudos apontarem que existe uma maior prevalência de periodontite apical em diabéticos ainda são poucas as evidências científicas sobre o assunto. Palavras-chave: periodontite apical, diabetes mellitus, endodontia, doença sistêmica.

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Definitions and Epidemiology of Endodontic Infections

Cited by 61 publications

References 56 publications

IDF Diabetes Atlas: Diabetes and oral health – A two-way relationship of clinical importance

IDF Diabetes Atlas: Diabetes and oral health – A two-way relationship of clinical importance

Fungi at the Scene of the Crime: Innocent Bystanders or Accomplices in Oral Infections?

Associação entre a periodontite apical e o diabetes mellitus: uma revisão da literatura

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