Degradation of benzoic acid in an advanced oxidation process: The effects of reducing agents

He, Dan; Zhang, Yingjie; Pei, Dan-Ni; Huang, Gui‐Xiang; Liu, Chang; Li, Jun; Yu, Han‐Qing

doi:10.1016/j.jhazmat.2019.121090

Cited by 88 publications

(31 citation statements)

References 42 publications

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“…Some recent studies have confirmed the redox activity of a mixture of ascorbic acid with Fe 2+ in the Fenton reaction [83,84]. For example, oxidation of benzoic acid by the Fenton reaction occurs more effectively in the presence of ascorbic acid [85]. The initial reactivity of ferrous ascorbate with hydrogen peroxide is the same as that of free ferrous ions.…”

Section: Discussionmentioning

confidence: 89%

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Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone

Timoshnikov

Kobzeva

Polyakov

et al. 2020

IJMS

107

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Ascorbic acid (AscH2) is one of the most important vitamins found in the human diet, with many biological functions including antioxidant, chelating, and coenzyme activities. Ascorbic acid is also widely used in medical practice especially for increasing iron absorption and as an adjuvant therapeutic in iron chelation therapy, but its mode of action and implications in iron metabolism and toxicity are not yet clear. In this study, we used UV–Vis spectrophotometry, NMR spectroscopy, and EPR spin trapping spectroscopy to investigate the antioxidant/pro-oxidant effects of ascorbic acid in reactions involving iron and the iron chelator deferiprone (L1). The experiments were carried out in a weak acidic (pH from 3 to 5) and neutral (pH 7.4) medium. Ascorbic acid exhibits predominantly pro-oxidant activity by reducing Fe3+ to Fe2+, followed by the formation of dehydroascorbic acid. As a result, ascorbic acid accelerates the redox cycle Fe3+ ↔ Fe2+ in the Fenton reaction, which leads to a significant increase in the yield of toxic hydroxyl radicals. The analysis of the experimental data suggests that despite a much lower stability constant of the iron–ascorbate complex compared to the FeL13 complex, ascorbic acid at high concentrations is able to substitute L1 in the FeL13 chelate complex resulting in the formation of mixed L12AscFe complex. This mixed chelate complex is redox stable at neutral pH = 7.4, but decomposes at pH = 4–5 during several minutes at sub-millimolar concentrations of ascorbic acid. The proposed mechanisms play a significant role in understanding the mechanism of action, pharmacological, therapeutic, and toxic effects of the interaction of ascorbic acid, iron, and L1.

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Section: Discussionmentioning

confidence: 89%

“…However, when Fe 2+ is oxidised to Fe 3+ , the reaction rate decreases by one order due to the slow reaction of Fe 3+ with hydrogen peroxide (see Scheme 3). Furthermore, in the presence of ascorbic acid the starting reaction rate is kept high due to the fast transition of Fe 3+ to Fe 2+ [85].…”

Section: Discussionmentioning

confidence: 99%

Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone

Timoshnikov

Kobzeva

Polyakov

et al. 2020

IJMS

107

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“…There are many examples describing the redox activity implications of a mixture of ascorbic acid with Fe 2+ in the Fenton reaction [ 30 , 95 , 96 , 97 , 98 ]. For example, the oxidation of benzoic acid by the Fenton reaction occurs more effectively in the presence of ascorbic acid [ 96 ]. It appears that the starting reaction rate of the ferrous–ascorbate complex with hydrogen peroxide is the same as free Fe 2+ .…”

Section: Iron Coordination and Redox Chemistry Of Ascorbic Acidmentioning

confidence: 99%

“…However, after Fe 2+ was oxidized to Fe 3+ , the reaction rate decreased by about one order. It was concluded that in the presence of ascorbic acid the starting reaction rate is kept high due, to the fast reduction of Fe 3+ [ 96 ].…”

Section: Iron Coordination and Redox Chemistry Of Ascorbic Acidmentioning

confidence: 99%

Trying to Solve the Puzzle of the Interaction of Ascorbic Acid and Iron: Redox, Chelation and Therapeutic Implications

et al. 2020

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Iron and ascorbic acid (vitamin C) are essential nutrients for the normal growth and development of humans, and their deficiency can result in serious diseases. Their interaction is of nutritional, physiological, pharmacological and toxicological interest, with major implications in health and disease. Millions of people are using pharmaceutical and nutraceutical preparations of these two nutrients, including ferrous ascorbate for the treatment of iron deficiency anaemia and ascorbate combination with deferoxamine for increasing iron excretion in iron overload. The main function and use of vitamin C is its antioxidant activity against reactive oxygen species, which are implicated in many diseases of free radical pathology, including biomolecular-, cellular- and tissue damage-related diseases, as well as cancer and ageing. Ascorbic acid and its metabolites, including the ascorbate anion and oxalate, have metal binding capacity and bind iron, copper and other metals. The biological roles of ascorbate as a vitamin are affected by metal complexation, in particular following binding with iron and copper. Ascorbate forms a complex with Fe3+ followed by reduction to Fe2+, which may potentiate free radical production. The biological and clinical activities of iron, ascorbate and the ascorbate–iron complex can also be affected by many nutrients and pharmaceutical preparations. Optimal therapeutic strategies of improved efficacy and lower toxicity could be designed for the use of ascorbate, iron and the iron–ascorbate complex in different clinical conditions based on their absorption, distribution, metabolism, excretion, toxicity (ADMET), pharmacokinetic, redox and other properties. Similar strategies could also be designed in relation to their interactions with food components and pharmaceuticals, as well as in relation to other aspects concerning personalized medicine.

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“… 3 − 6 Photo-Fenton catalysis is an advanced oxidation process that attracted significant attention for the production of oxide species (·OH), which are efficient oxidants with high redox potential. 7 , 8 In particular, photo-Fenton catalysts based on transition metal oxides (e.g., Fe, Co, and Cu) have been studied extensively because they are inexpensive, environmentally benign, magnetically recyclable, and exhibit visible light responses. 9 − 13 Among these metal oxides, spinel-type cobalt ferrite (CoFe 2 O 4 ) has been intensively studied for degradation of organic dyes due to its excellent stability, separation, and catalytic activity.…”

Section: Introductionmentioning

confidence: 99%

Direct Synthesis of Magnetic CoFe₂O₄ Nanoparticles as Recyclable Photo-Fenton Catalysts for Removing Organic Dyes

Cao

Zuo

2020

ACS Omega

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Herein, CoFe 2 O 4 nanoparticles were directly synthesized through a solution combustion method using ferric nitrate, cobalt nitrate, and glycine as raw materials. The effects of glycine on the phase composition and magnetic properties of the CoFe 2 O 4 products were investigated. When the fuel/ferric nitrate ratio was 0.8, the obtained product was pure CoFe 2 O 4 with an average particle size of 25 nm. Furthermore, the saturation magnetization is 77.3 emu/g, which is about 95.7% that of CoFe 2 O 4 bulk materials at room temperature and good for recycling. The photo-Fenton catalytic properties of CoFe 2 O 4 were investigated for assessing its efficacy in removing dyes. It could degrade the 20 ppm MB in 75 min. To improve the photo-Fenton catalytic performance, NH 4 HCO 3 and glucose were employed as additives. Due to the pores formed by NH 4 HCO 3 and glucose, the G-CoFe 2 O 4 and N-CoFe 2 O 4 could degrade the 20 ppm MB in 40 and 25 min, respectively. The results indicated that these additives can effectively improve the catalytic activity of CoFe 2 O 4 . The modified CoFe 2 O 4 is a promising alternative recyclable photo-Fenton catalyst for removing organic dyes.

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Degradation of benzoic acid in an advanced oxidation process: The effects of reducing agents

Cited by 88 publications

References 42 publications

Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone

Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone

Trying to Solve the Puzzle of the Interaction of Ascorbic Acid and Iron: Redox, Chelation and Therapeutic Implications

Direct Synthesis of Magnetic CoFe₂O₄ Nanoparticles as Recyclable Photo-Fenton Catalysts for Removing Organic Dyes

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Degradation of benzoic acid in an advanced oxidation process: The effects of reducing agents

Cited by 88 publications

References 42 publications

Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone

Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone

Trying to Solve the Puzzle of the Interaction of Ascorbic Acid and Iron: Redox, Chelation and Therapeutic Implications

Direct Synthesis of Magnetic CoFe2O4 Nanoparticles as Recyclable Photo-Fenton Catalysts for Removing Organic Dyes

Contact Info

Product

Resources

About

Direct Synthesis of Magnetic CoFe₂O₄ Nanoparticles as Recyclable Photo-Fenton Catalysts for Removing Organic Dyes