Degradation of dioxin-like compounds by microorganisms

Wittich, Rolf-Michael

doi:10.1007/s002530051203

Cited by 156 publications

(95 citation statements)

References 91 publications

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“…The ability to use various aromatic compounds to serve as sources of carbon and energy is widespread in bacteria, and in the natural environment these bacteria contribute greatly to the breakdown of aromatic compounds and to the global carbon cycle (Wittich, 1998;Esteve-Nú ñ ez et al, 2001;Furukawa et al, 2004). The majority of reported bacterial aromatic degradation processes are aerobic (Gibson and Harwood, 2002) and comprise series of enzymes that are usually categorized as either 'upper'-or 'lower'-pathway enzymes (Williams and Sayers, 1994).…”

Section: Introductionmentioning

confidence: 99%

Novel organization of aromatic degradation pathway genes in a microbial community as revealed by metagenomic analysis

et al. 2009

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Several types of environmental bacteria that can aerobically degrade various aromatic compounds have been identified. The catabolic genes in these bacteria have generally been found to form operons, which promote efficient and complete degradation. However, little is known about the degradation pathways in bacteria that are difficult to culture in the laboratory. By functionally screening a metagenomic library created from activated sludge, we had earlier identified 91 fosmid clones carrying genes for extradiol dioxygenase (EDO), a key enzyme in the degradation of aromatic compounds. In this study, we analyzed 38 of these fosmids for the presence and organization of novel genes for aromatics degradation. Only two of the metagenomic clones contained complete degradation pathways similar to those found in known aromatic compound-utilizing bacteria. The rest of the clones contained only subsets of the pathway genes, with novel gene arrangements. A circular 36.7-kb DNA form was assembled from the sequences of clones carrying genes belonging to a novel EDO subfamily. This plasmid-like DNA form, designated pSKYE1, possessed genes for DNA replication and stable maintenance as well as a small set of genes for phenol degradation; the encoded enzymes, phenol hydroxylase and EDO, are capable of the detoxification of aromatic compounds. This gene set was found in 20 of the 38 analyzed clones, suggesting that this 'detoxification apparatus' may be widespread in the environment.

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Section: Introductionmentioning

confidence: 99%

Novel organization of aromatic degradation pathway genes in a microbial community as revealed by metagenomic analysis

et al. 2009

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“…Nonhalogenated dibenzofuran (DF) has been used as a model compound to study the biodegradation of PCDDs and PCDFs. Some bacterial strains capable of metabolizing DF have been isolated, and in most cases, the ring cleavage reactions have been elucidated [2,5,6,11,23,24,28,29,32]. Some of these-such as Sphingomonas sp.…”

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confidence: 99%

Biodegradation of Dibenzofuran by Janibacter terrae Strain XJ-1

Jin

Zhu

et al. 2006

Curr Microbiol

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Abstract. The dibenzofuran (DF)-degrading bacterium, Janibacter terrae strain XJ-1, was isolated from sediment from East Lake in Wuhan, China. This strain grows aerobically on DF as the sole source of carbon and energy; it has a doubling time of 12 hours at 30°C; and it almost completely degraded 100 mg/L )1 DF in 5 days, producing 2,2¢,3-trihydroxybiphenyl, salicylic acid, gentisic acid, and other metabolites. The dbdA (DF dioxygenase) gene cluster in the strain is almost identical to that on a large plasmid in Terrabacter sp. YK3. Unlike Janibacter sp. strain YY-1, XJ-1 accumulates gentisic acid rather than catechol as a final product of DF degradation.

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“…Lightly chlorinated PCDD/Fs may be biotransformed or mineralized under aerobic conditions (Wittich 1998;Yoshida et al 2005), while highly chlorinated PCDD/Fs undergo reductive dechlorination under anaerobic conditions (Adriaens et al, 1995;Barkowskii & Adriaens 1996Ballerstedt et al, 1997;Bunge et al, 2003;Fennell et al 2004). Recently two bacterial strains have been identified which dechlorinate PCDDs under anaerobic conditions -Dehalococcoides sp.…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, these organohalides are problematic because of their greater stability compared to less chlorinated compounds, which are more readily degraded by aerobic microorganisms (Häggblom, 1992;Wittich, 1998). However, under anaerobic conditions, certain dechlorinating bacteria can use a variety of polychlorinated compounds as a terminal electron acceptor in the process of respiratory reductive dehalogenation or dehalorespiration (Bedard and Quensen, 1995;Bedard, 2008;Hiraishi, 2008).…”

Section: Introductionmentioning

confidence: 99%

“…Biotransformation of PCDD/Fs occurs under both aerobic and anaerobic conditions (Wittich 1998;Adriaens et al, 1995;Barkowskii & Adriaens 1996Ballerstedt et al, 1997;Yoshida et al 2005). Lightly chlorinated PCDD/Fs may be biotransformed or mineralized under aerobic conditions (Wittich 1998;Yoshida et al 2005), while highly chlorinated PCDD/Fs undergo reductive dechlorination under anaerobic conditions (Adriaens et al, 1995;Barkowskii & Adriaens 1996Ballerstedt et al, 1997;Bunge et al, 2003;Fennell et al 2004).…”

Section: Introductionmentioning

confidence: 99%

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Quantifying Enhanced Microbial Dehalogenation Impacting the Fate and Transport of Organohalide Mixtures in Contaminated Sediments

Häggblom¹,

Fennell²,

Rodenburg³

et al. 2012

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Standard Form 298 (Rev. 8/98) REPORT DOCUMENTATION PAGEPrescribed by ANSI Std. Z39.18 Form Approved OMB No. 0704-0188The public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing the burden, to the Department of Defense, Executive Services and Communications Directorate (0704-0188). Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to any penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ORGANIZATION. 1. REPORT DATE (DD-MM-YYYY)2. REPORT TYPE 3. DATES COVERED (From -To) 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER AUTHOR(S) PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR'S ACRONYM(S) SPONSOR/MONITOR'S REPORT NUMBER(S)12 SERDPThe project investigated techniques and amendments to enhance microbial dehalogenation in sediments contaminated with organohalide mixtures and developed methods and tools to monitor the effectiveness of biostimulation processes. Micro-and mesocosm studies with organohalide-contaminated sediments demonstrated that these contain diverse communities of dehalogenating microorganisms. Dechlorination of historical PCB and PCDD/F contaminant mixtures can be stimulated by addition of amendments and/or bioaugmentation with dechlorinating bacteria. The enhanced dechlorination correlates with increased numbers of dehalorespirer populations and reductive dehalogenase genes. Identification of the specific microbial members associated with PCB-and PCDD/F-dechlorinating activity should allow for better strategies to enhance dehalogenation. The results provide compelling evidence to support further testing and development of biostimulation and bioaugmentation with dehalorespiring bacteria as environmentally less invasive and lower cost alternatives for in situ treatment of PCB impacted sediments. Anacostia microcosms compared to the sum of all di-through deca-chlorinated biphenyls (homolog groups 2 through 10). Analyses of the dry matter content, the total PCB concentration, the average number and percentage of chlorines less than 4 and 6, respectively and in soil samples and commercial Aroclor mixtures. Table 6-2. Analyses of total bacteria, putative dechlorinating and PCB degrading bacteria and the number of dechlorinating bacteria in soil samples. Table 6-3. The potential dechlorination activi...

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Degradation of dioxin-like compounds by microorganisms

Cited by 156 publications

References 91 publications

Novel organization of aromatic degradation pathway genes in a microbial community as revealed by metagenomic analysis

Novel organization of aromatic degradation pathway genes in a microbial community as revealed by metagenomic analysis

Biodegradation of Dibenzofuran by Janibacter terrae Strain XJ-1

Quantifying Enhanced Microbial Dehalogenation Impacting the Fate and Transport of Organohalide Mixtures in Contaminated Sediments

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