Degradation of furazolidone by bacteria Acinetobacter calcoaceticus T32, Pseudomonas putida SP1 and Proteus mirabilis V7

Pyoverdine secreted by Pseudomonas aeruginosa as a biological recognition element for the fluorescent detection of furazolidone

“…The furazolidone at concentration of 20 mM could be merely distinguished by naked eyes. Traditional HPLC method was finished within about 4 min, but was nonvisible by naked eyes (Mustafa et al, 1985;Zhang et al, 2013). Compared with HPLC, furazolidone detection based on the fluorescent biosensor is a more rapid (within a few seconds) and visible method, and will be potentially applied for the furazolidone detection without large and sophisticated equipment.…”

Bacteria-mediated bisphenol A degradation

“…Among all these methods, biodegradation has been proved to be an advanced technique to remove various pollutants from the environment. In our lab, efforts were made to investigate the biotransformation of heavy metals, and biodegradation of sulfonamide drugs, nitrofurans drugs, and EDCs by bacterial strains and their potential application in bioremediation (Zhang et al 2012a(Zhang et al , 2012b(Zhang et al , 2012c(Zhang et al , 2013. Bacterial community is readily catabolized to BPA, and BPA-degrading bacterial strains were isolated and identified from various environments (Kang et al 2006a).…”

Electrochemical degradation of nitrofurans furazolidone by cathode: Characterization, pathway and antibacterial activity analysis

“…China, the world's largest producer and consumer of pharmaceutical products, consumes more than 25,000 tons antibiotics annually [3]. Furazolidone (FZD), namely 3-(5-nitrofurfurylideneamino)-2-oxazolidinone, is a typical example of nitrofurans antibiotics, has been widely used for more than 30 years as an antibacterial and antiprotozoal feed additive for poultry, cattle and farmed fish as well as human medicine for the eradication of Helicobacter pylori [4]. Long-term studies with experimental animals indicated the mutagenic, genotoxic and potentially carcinogenic characteristics of FZD and its metabolite 3-amino-2-oxazolidinone (AOZ) [5].…”

“…However, due to the low production cost and high effectiveness of FZD, it is still being illegally used in a relatively large scale across the world, particularly in developing countries [6]. In general, animals and human had a very low assimilation rate of the FZD, thus a majority of the FZD used in farms and aquaculture was finally released into the environments [4]. As a result, FZD residues and its high toxic biological metabolite AOZ were frequently detected in some aquatic species, aquatic products, pond water and sediments [5,[7][8][9].…”

“…Generally, bacterial degradation of FZD suffered from lower degradation rates due to its antimicrobial nature [4,10], while physical-chemical methods such as electron irradiation are needed to provide more energy required for FZD degradation [11]. The electrochemical reduction is an emerging technology that could reductively degrade various refractory pollutants with features of higher removal efficiency, environmental friendly and low-cost [12][13][14][15][16][17][18].…”