Degradation Resistance and In Vitro Cytocompatibility of Iron-Containing Coatings Developed on WE43 Magnesium Alloy by Micro-Arc Oxidation

Zhang, Rongfa; Zhang, Zeyu; Zhu, Yuanyuan; Zhao, Rongfang; Zhang, Shufang; Shi, Xiaoting; Li, Guoqiang; Chen, Zhiyong; Zhao, Ying

doi:10.3390/coatings10111138

Cited by 8 publications

(5 citation statements)

References 33 publications

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“…Furthermore, the CS/2MgO-GO coated specimen demonstrated the greatest ALP activity at both time points tested, implying a greater potential for cell differentiation. The increased corrosion rate in uncoated Mg alloys resulted in a greater release of Mg ions [43][44][45][46][47][48][49][50][51][52], causing the culture medium to become excessively alkalinization and local hydrogen evolution. All of these were detrimental to cell differentiation.…”

Section: Cytotoxicity Assaymentioning

confidence: 99%

Dual Synergistic Effects of MgO-GO Fillers on Degradation Behavior, Biocompatibility and Antibacterial Activities of Chitosan Coated Mg Alloy

et al. 2022

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The aim of this work was to establish and characterize chitosan/graphene oxide- magnesium oxide (CS/GO-MgO) nanocomposite coatings on biodegradable magnesium-zinc-cerium (Mg-Zn-Ce) alloy. In comparison to that of pure CS coatings, all composite coatings encapsulating GO-MgO had better adhesion strength to the Mg-Zn-Ce alloy substrate. The result depicted that the co-encapsulation of GO-MgO into the CS layer leads to diminish of contact angle value and hence escalates the hydrophilic characteristic of coated Mg alloy. The electrochemical test demonstrated that the CS/GO-MgO coatings significantly increased the corrosion resistance because of the synergistic effect of the GO and MgO inside the CS coating. The composite coating escalated cell viability and cell differentiation, according to cytocompatibility tests due to the presence of GO and MgO within the CS. The inclusion of GO-MgO in CS film, on the other hand, accelerates the formation of hydroxyapatite (HA) during 14 days immersion in SBF. Immersion results, including weight loss and hydrogen evolution tests, presented that CS/GO-MgO coating enables a considerably reduced degradation rate of Mg-Zn-Ce alloy when compared to the bare alloy. In terms of antibacterial-inhibition properties, the GO-MgO/CS coatings on Mg substrates showed antibacterial activity against Escherichia coli (E. coli), with a large inhibition area around the specimens, particularly for the coating containing a higher concentration of GO-MgO. Bacterial growth was not inhibited by the bare Mg alloy samples. The CS/GO-MgO composite coating is regarded as a great film to enhance the corrosion resistance, bioactivity, and antibacterial performance of Mg alloy implants.

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Section: Cytotoxicity Assaymentioning

confidence: 99%

Dual Synergistic Effects of MgO-GO Fillers on Degradation Behavior, Biocompatibility and Antibacterial Activities of Chitosan Coated Mg Alloy

et al. 2022

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“…However, magnesium alloys have certain disadvantages such as poor corrosion and wear resistance [4,5]. Currently, surface phosphating [6][7][8], chemical conversion [9], anodic oxidation, micro-arc oxidation (MAO) [10,11], vapor deposition [12], and polymer coatings are effective surface modification methods of magnesium alloys in industrial engineering. Among these, MAO has become an important environment-friendly process for the surface protection of magnesium alloys to create high-strength ceramic coatings with excellent hardness [13].…”

Section: Introductionmentioning

confidence: 99%

Effect of Graphite Content on the Conductivity, Wear Behavior, and Corrosion Resistance of the Organic Layer on Magnesium Alloy MAO Coatings

Leng

Wang

et al. 2022

Coatings

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To impart electrical conductivity on magnesium alloy micro-arc oxidation coatings, a graphite/epoxy conductive layer was prepared on the surface of a ceramic layer in this work, focusing on wear behavior and corrosion resistance of the coating. At a graphite weight of 80 wt%, the square resistance of the coating decreased to 217.6 kΩ/□, and it exhibited good resistance. Combined with the distribution of graphite particles in the coating and the change in surface resistance, we determined that the conductive mechanism of the coating occurred through quantum tunneling when the graphite content was 60 wt%. When the graphite content increased from 60 to 80 and 100 wt%, the formation of conductive paths on the surface of the coating further improved the conductivity. The hardness of the organic coatings was positively related to the graphite content. Analysis of the wear scars and wear debris after dry friction and wear testing showed that the wear forms of the coating consisted of abrasive wear when the graphite content was in the range of 20–40 wt%. When the graphite content was in the range of 60–100 wt%, the wear forms of the coating consisted of abrasive wear and peeling wear.

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“…Among various preparation methods of coatings such as micro-arc oxidation (MAO) [ 8 , 9 ], electrophoretic deposition [ 10 , 11 ], layer-by-layer assembly [ 12 , 13 ], chemical vapor deposition [ 14 ] and chemical conversion [ 15 , 16 ], MAO has been extensively used for surface modification of Mg-based alloys because of its remarkable wear resistance as well as high hardness [ 17 ]. However, the MAO coating with porous structures is vulnerable to penetration by a corrosive medium.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Degradation and Photoactivated Antibacterial Activity of a Hemin-CaP Microsphere-Loaded Coating on Pure Magnesium

Long

Song

Tian

et al. 2022

JFB

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Photoactivated sterilization has received more attention in dealing with implant-associated infections due to its advantages of rapid and effective bacteriostasis and broad-spectrum antibacterial activity. Herein, a micro-arc oxidation (MAO)/polymethyltrimethoxysilane (PMTMS)@hemin-induced calcium-bearing phosphate microsphere (Hemin-CaP) coating was prepared on pure magnesium (Mg) via MAO processing and dipping treatments. The morphology and composition of the coating were characterized via scanning electron microscopy, Fourier transform infrared spectrometer, X-ray diffractometer and X-ray photoelectron spectrometer. Corrosion behavior was evaluated through electrochemical and hydrogen evolution tests. The release of Fe3+ ions at different immersion times was measured with an atomic absorption spectrophotometer. Antibacterial performance and cytotoxicity were assessed using the spread plate method, MTT assay and live/dead staining experiment. The results showed that the corrosion current density of the MAO/PMTMS@(Hemin-CaP) coating (4.41 × 10−8 A·cm−2) was decreased by two orders of magnitude compared to that of pure Mg (3.12 × 10−6 A·cm−2). Photoactivated antibacterial efficiencies of the Hemin-CaP microspheres and MAO/PMTMS@(Hemin-CaP) coating reached about 99% and 92%, respectively, which we attributed to the photothermal and photodynamic properties of hemin with a porphyrin ring. Moreover, based on the release of Fe3+ ions, the MC3T3-E1 pre-osteoblasts’ viability reached up to 125% after a 72 h culture, indicating a positive effect of the coating in promoting cell growth. Thus, this novel composite coating holds a promising application as bone implants.

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Degradation Resistance and In Vitro Cytocompatibility of Iron-Containing Coatings Developed on WE43 Magnesium Alloy by Micro-Arc Oxidation

Cited by 8 publications

References 33 publications

Dual Synergistic Effects of MgO-GO Fillers on Degradation Behavior, Biocompatibility and Antibacterial Activities of Chitosan Coated Mg Alloy

Dual Synergistic Effects of MgO-GO Fillers on Degradation Behavior, Biocompatibility and Antibacterial Activities of Chitosan Coated Mg Alloy

Effect of Graphite Content on the Conductivity, Wear Behavior, and Corrosion Resistance of the Organic Layer on Magnesium Alloy MAO Coatings

In Vitro Degradation and Photoactivated Antibacterial Activity of a Hemin-CaP Microsphere-Loaded Coating on Pure Magnesium

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