Metal-organic frameworks explicit the consequence of these frameworks with adjustable implementations, namely, energy storage gadgets of magnificent electrode materials, gas store, heterogeneous catalysis, environmental hazard, estimation of chemicals, recognizing of definite gases, controlling solids, and supercapacitors. In this paper, we give explicit expression of the reverse general Randic index, the reverse atom bond connectivity index, the reverse geometric arithmetic index, the reverse forgotten index, the reverse Balaban index, the reverse augmented index, and different types of reverse Zagreb indices of the metal-organic framework M1TPyP-M2 (TPyP = 5, 10, 15, 20-tetrakis (4-pyridyl) porphyrin and M1, M2 = Fe and Co). A graphical comparison of the calculated different types of the reverse degree based topological indices with the aid of the numerical values is also included.