Delayed Calcineurin Inhibitor Introduction Without Antibody Induction in Liver Transplantation Is Safe and Helps Preserve Kidney Function

Tovikkai, Chutwichai; Limsrichamrern, Somchai; Dumronggittigule, Wethit; Sirivatanauksorn, Yongyut; Kositamongkol, Prawat; Mahawithitwong, Prawej; Sangserestid, Pholasith; Assawasirisin, Charnwit

doi:10.1016/j.transproceed.2020.11.005

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…Our center promoted the concept of 'enhanced recovery after surgery' (ERAS) to achieve early extubation, early functional exercise, and a shortened length of stay at the hospital (37). Complications in the early postoperative period are important concerns in LT. AKI was a prevalent complication, and its incidence was 4.0% in our study (38,39). The incidence of AKI in previous reports ranged from 0% to 16.7% (40,41).…”

Section: Discussionsupporting

confidence: 43%

Application of various surgical techniques in liver transplantation: a retrospective study

Chen¹,

Wang²,

Chen³

et al. 2021

Ann Transl Med

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Background: Surgical techniques of liver transplantation have continually evolved and have been modified.We retrospectively analyzed a single-center case series and compared the advantages and disadvantages of each method.Methods: Six-hundred and seventy-four recipients' perioperative data were assessed and analyzed stratified by different surgical technics [modified classic (MC), modified piggyback (MPB) and classic piggyback (CPB)].Results: MELD score and Child-Pugh scores was significantly higher in CPB groups (P=0.008 and 0.003, respectively). Anhepatic time in MPB group was longer than those in CPB group (P<0.05). The operation duration in MPB group was significantly longer than those in MC group and CPB group (P=0.003). Three patients had outflow obstruction (P=0.035). The overall survival in MPB group were better than those in MC group and CPB group in general comparison (P<0.001). In patients with preoperative creatine >120 μmol/L, the overall survival in MC group was worst (P<0.001). In patients with a high MELD score (>24), the overall survival in MPB group tended to be the best (P<0.001). Conclusions:The advantages and disadvantages are different for these three surgical techniques. A reasonable operation technique should be adopted considering the patient's unique condition to ensure the stability of hemodynamics.

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