Delayed Diagnosis of Acromegaly in an Elderly Adult that Initially Presented as Cutis Verticis Gyrata

Araujo, Karin Milleni; Silva, Flavia T. da; Bestane, Gabriela Camargo; Soares, Marcella Maria; Denadai, Rafael

doi:10.1111/jgs.13990

Cited by 4 publications

(3 citation statements)

References 9 publications

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“…The influence of underlying systemic diseases must be considered on the patient's quality of life. For example, the majority of individuals with acromegaly experience depression, sleep difficulties, impaired body image, diabetes mellitus, and arterial hypertension, all of which contribute to poor quality of life and increased morbidity and mortality as a result of prolonged exposure to elevated growth hormone secretion (18) . Chronic nature and low mortality may underestimate the importance of skin disease.…”

Section: Discussionmentioning

confidence: 99%

Cutis Verticis Gyrata and Quality of Life: Clinical Report of 13 Cases

Mohammed¹,

Reygagne²,

Assouly³

et al. 2021

The Egyptian Journal of Hospital Medicine

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Background: The quality of life of patients with Cutis Verticis Gyrata (CVG) has not been previously investigated in the literature. Objective: Description of features and evaluation of quality of life of CVG patients. Materials and methods: We employed a mixed methods study. We retrospectively collected data from the clinical database from 2012 to 2020. We selected 17 clinically diagnosed CVG patients and prospectively evaluated the quality of life of these CVG patients. Results: Out of 13 patients, 11 patients were in between the 14-47 age group. The majority of them were male (77%), Caucasian (54%), had no significant family history (92.3%), and had the age of onset below < 30 years (69.2%). The majority of the patients had a secondary form of CVG (54%) followed by a primary essential form of CVG (46.1%). The CVG had a small effect on the majority of patient's quality of life (77%), and a majority of patients were not taking any treatment (69.2%) Conclusion: In our study, the CVG was shown to have a small effect on the patient's quality of life.

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Section: Discussionmentioning

confidence: 99%

Cutis Verticis Gyrata and Quality of Life: Clinical Report of 13 Cases

Mohammed¹,

Reygagne²,

Assouly³

et al. 2021

The Egyptian Journal of Hospital Medicine

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“…The associated systemic diseases in secondary cutis verticis gyrata include cerebriform intradermal nevi, neurofibromas, acromegaly, myxoedema, Touraine Solente Gole syndrome, leukemia, acanthosis nigricans, and paraneoplastic syndromes [2,6]. Therefore it is important to take a thorough medical history as cutis verticis gyrata may be the initial sign of one of these underlying diseases [7,8].…”

Section: Discussionmentioning

confidence: 99%

Cutis verticis gyrata

Yagerman

Callahan²,

Terushkin³

et al. 2016

Dermatology Online Journal

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A 61-year-old man was seen in the Ulcer Clinic at Bellevue Hospital Center and was referred to Dermatology Clinic for evaluation of a leonine facies. The patient noted progressive wrinkling and thickening of the skin of his forehead over the last thirty-eight years. The change was gradual, and he brought photographs that showed the deepening of the furrows over time. The patient denied any other skin lesions, dysasthesias, or active infections. Past medical history included pre-diabetes, hyperlipidemia, and chronic venous insufficiency. PHYSICAL EXAMINATION:On the central forehead and glabella were exaggerated skin folds that were interrupted by deep-undulating furrows (Figure 1). The scalp was normal. The facial folds gave the appearance of a leonine facies.

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“…Antrinio CVG priežastimi gali būti neurofibromatozė, tuberozine sklerozė, impetiga, atopinis dermatitas, psoriazė, cerebriforminis intraderminis apgamas, leukemija, amiloidozė, skydliaukės susirgimai, sifilis, su žmogaus imunodeficito virusu (ŽIV) susijusi lipodistrofija ar kitos ligos [9], todėl ir odos pažeidimai gali turėti įvairių, šiems susirgimams būdingų požymių. Svarbu atpažinti antriniam CVG būdingus odos pakitimus, nes jie gali signalizuoti apie ligą, kurią laiku diagnozavus būtų galima užtikrinti savalaikį gydymą, ar net užkirsti kelią galimoms komplikacijoms [16,17]. CVG diagnostika.…”

Section: Tyrimo Medžiaga Ir Metodaiunclassified

Cutis Verticis Gyrata – Klinika, Diagnostika, Gydymas

Berškys

2024

Health Sciences

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Cutis verticis gyrata (CVG) – reta odos patologija, kuri dažniausiai pasireiškia galvos smegenų žievės vingius primenančių klosčių formavimusi skalpo odoje. Naujausioje klasifikacijoje CVG suskirstyta į 3 tipus, atsižvelgiant į jiems būdingą odos pakitimų morfologiją ir kitą patologiją. Šio darbo tikslas yra apžvelgti cutis verticis gyrata kliniką, diagnostiką ir gydymą, išanalizavus aktualią mokslinę literatūrą. Literatūros analizė atskleidė, jog pirminio esencialinio CVG klinika apsiriboja odos pakitimais, o cutis verticis gyrata protinės negalios tipui. Be odos pažeidimų, būdingi ir neuropsichiatriniai ar oftalmologiniai radiniai. Antrinio CVG klinikai būdingi odos pažeidimus sukėlusios patologijos požymiai. Diagnostikos tikslas yra nustatyti pakitimus sukėlusią priežastį ir konkretų atvejį priskirti vienam iš CVG tipų. Tam taikomas ištyrimas, galintis apimti anamnezės surinkimą, fizinį ištyrimą, odos biopsiją bei laboratorinius ir vaizdinius tyrimus. Gydymo taktikos pasirinkimas priklauso nuo ligos tipo, paciento norų bei pažeidimo laipsnio. Antrinio CVG atveju, gydymo pagrindas yra CVG sukėlusios priežasties korekcija. Visai atvejais būtina užtikrinti pažeistos odos higieną. Odos pažeidimus galima koreguoti chirurginėmis priemonėmis ar pasitelkiant mažiau invazyvias, vietines procedūras.

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Delayed Diagnosis of Acromegaly in an Elderly Adult that Initially Presented as Cutis Verticis Gyrata

Cited by 4 publications

References 9 publications

Cutis Verticis Gyrata and Quality of Life: Clinical Report of 13 Cases

Cutis Verticis Gyrata and Quality of Life: Clinical Report of 13 Cases

Cutis verticis gyrata

Cutis Verticis Gyrata – Klinika, Diagnostika, Gydymas

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