Delayed Fertilization and Preimplantation Loss in Senescent Golden Hamsters

Parkening, T. A.; Soderwall, A. L.

doi:10.1095/biolreprod12.5.618

Cited by 26 publications

(25 citation statements)

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“…This finding is in agreement with other studies examining the ovulation in aged hamsters [9,10,12,18,24,25], mice [2,13] and rats [14]. However, little attention has been paid to the timing of ovulation.…”

Section: Ovulation and Fertilizationsupporting

confidence: 92%

“…These authors did not examine the exact time of ovulation. However, considering the finding that ovulation occurs 8 h after estrus in the hamster [26], a tendency toward delayed ovulation can be found in their results [12,18]. Furthermore, according to their data, the mean number of ova collected at 1 h after the estimated time of ovulation was significantly lower in aged hamsters compared with young hamsters.…”

Section: Ovulation and Fertilizationmentioning

confidence: 91%

“…During anaphase II the bivalents move to opposite ends of the spindle, which rotates gradually through 90°, ability with aging results in the decline of litter sizes. Retarded development may result in reduction in implantations and litter sizes in aged hamsters [7][8][9][10][11][12]20]. In our preliminary study, about 25-30% of decline was observed in litter size of 43-week old hamsters as compared with younger females [20].…”

Section: Abnormalities In Fertilizationmentioning

confidence: 95%

“…In the present study, both ovulation and sperm penetration were found to be delayed in aged hamsters. Parkening and Soderwall [12,18] have reported that the majority of ova recovered from aged hamsters mated with young males exhibited a 2 to 5 h delay in fertilization. These authors did not examine the exact time of ovulation.…”

Section: Ovulation and Fertilizationmentioning

confidence: 99%

See 3 more Smart Citations

Delay in Ovulation and Fertilization and Asynchronous Pronuclear Development in Aged Hamsters.

Suzuki

Moriguchi

Kida

et al. 1996

Journal of Reproduction and Development

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Section: Ovulation and Fertilizationsupporting

confidence: 92%

Section: Ovulation and Fertilizationmentioning

confidence: 91%

Section: Abnormalities In Fertilizationmentioning

confidence: 95%

Section: Ovulation and Fertilizationmentioning

confidence: 99%

See 2 more Smart Citations

Delay in Ovulation and Fertilization and Asynchronous Pronuclear Development in Aged Hamsters.

Suzuki

Moriguchi

Kida

et al. 1996

Journal of Reproduction and Development

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“…A progressive decrease of litter size has been described in polytocous animals, such as rats [1][2][3], mice [4][5][6][7], golden hamsters [8], and rabbits [9]. More importantly, this phenomenon of continuous decline of fecundity with age has also been confirmed in women over 35 years old [10][11][12].…”

mentioning

confidence: 99%

Determinants of uterine aging: lessons from rodent models

Kong

Zhang

Chen

et al. 2012

Sci. China Life Sci.

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The uterus is an indispensable organ for the development of a new life in eutherian mammals. The female mammalian reproductive capacity diminishes with age. In this respect, the senescence of uterine endometrium is convinced to contribute to this failure. This review focuses on the physiological function of the uterus and the related influence of aging mainly in rodent models. A better understanding of the underlying mechanisms governing the process of uterine aging is hoped to generate new strategies to prolong the reproductive lifespan in humans. . More importantly, this phenomenon of continuous decline of fecundity with age has also been confirmed in women over 35 years old [10][11][12]. The success of reproduction in eutherian mammals requires the uterus, a unique organ in the viviparity compared to other organisms ensuring full development of the new life in the maternal body [13]. The endometrial environment of uteri is proved to be one of the critical aspects to determine the reproductive capacity [14] and uterine factor has been proved to be critical for the decline of fecundity in both rodents and humans [4,15]. Most of the available information on uterine aging derives from studies on rats and mice [16]. In these species, life span is short and aging animal model can be easily established. This review focuses on the physiological function of the uterus and the related influence of aging mainly in rodent models. determinants, uterine aging, rodent models

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Preimplantation development, fate of the zona pellucida, and observations on the glycogen‐rich oviduct of the little bulldog bat, Noctilio albiventris

Rasweiler

1977

Am. J. Anat.

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The reproductive biology of Noctilio albiventris was investigated histologically in 112 females collected at the start of their synchronized breeding season during two different sampling years in the Cauca Valley of Colombia. Both ovaries were functional, but the animals were generally observed to be monovular. Embryonic development in the oviduct was found to proceed to blastocyst formation and loss of the zona pellucida. In 22 animals the discarded zona had been left behind in the oviduct upon passage of the embryo into the uterus and was still undissolved at the time of amniogenesis, the latest stage examined. The zonae which had passed into the uterus with the embryos often exhibited signs of dissolution. Most of the early blastocyts were morphologically distinctive, lacking a typical inner cell mass and being instead largely bilaminar. Degenerating ova from previous ovulations were found in the oviducts of two pregnant bats, suggesting that Noctilio may be another species in which the embryo stimulates its own escape from the oviduct. During tubal passage of the embryo the secretory cells of the oviductal ampulla and isthmus exhibited a transient engorgement with glycogen, particularly on the side ipsilateral to the new corpus luteum.

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Delayed Fertilization and Preimplantation Loss in Senescent Golden Hamsters

Cited by 26 publications

References 0 publications

Delay in Ovulation and Fertilization and Asynchronous Pronuclear Development in Aged Hamsters.

Delay in Ovulation and Fertilization and Asynchronous Pronuclear Development in Aged Hamsters.

Determinants of uterine aging: lessons from rodent models

Preimplantation development, fate of the zona pellucida, and observations on the glycogen‐rich oviduct of the little bulldog bat, Noctilio albiventris

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