We study all four types of finite-time future singularities emerging in late-time accelerating (effective quintessence/phantom) era from F(R, G)-gravity, where R and G are the Ricci scalar and the Gauss-Bonnet invariant, respectively. As an explicit example of F(R, G)-gravity, we also investigate modified Gauss-Bonnet gravity, so-called F (G)-gravity. In particular, we reconstruct the F (G)-gravity and F(R, G)-gravity models where accelerating cosmologies realizing the finite-time future singularities emerge. Furthermore, we discuss a possible way to cure the finite-time future singularities in F (G)-gravity and F(R, G)-gravity by taking into account higher-order curvature corrections. The example of non-singular realistic modified Gauss-Bonnet gravity is presented.It turns out that adding such non-singular modified gravity to singular Dark Energy makes the combined theory to be non-singular one as well.PACS numbers: 04.50. Kd, 95.36.+x, Recent observations have implied that the current expansion of the universe is accelerating [1, 2]. There exist two broad categories to explain this phenomena [3][4][5][6][7][8][9][10][11][12]. One is the introduction of "dark energy" in the framework of general relativity. The other is the investigation of a modified gravitational theory, e.g., f (R)-gravity, in which the action is described by the Ricci scalar R plus an arbitrary function f (R) of R (for reviews, see [6][7][8][9][10] It is clear that singular dark energy may lead to various instabilities in the current universe