Dementia diagnosis in developing countries: a cross-cultural validation study

Prince, Martin; Acosta, Daisy; Chiu, Helen F.K.; Scazufca, Márcia; Varghese, Mathew

doi:10.1016/s0140-6736(03)12772-9

Cited by 507 publications

(600 citation statements)

References 27 publications

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“…58,59 The clinical battery has been referenced as a standard by several clinical studies that indicate that they used NINCDS/ADRDA and CERAD criteria for AD. In those instances, however, it is difficult to know whether the CERAD clinical battery or the CERAD clinical criteria were used.…”

Section: Main Uses and Findingsmentioning

confidence: 99%

Consortium to Establish a Registry for Alzheimer's Disease (CERAD): The first twenty years

Fillenbaum

Belle

Morris

et al. 2008

Alzheimer's & Dementia

384

274

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The Consortium to Establish a Registry for Alzheimer's Disease (CERAD) was funded by the National Institute on Aging in 1986 to develop standardized, validated measures for the assessment of Alzheimer's disease (AD). The present report describes the measures that CERAD developed during its first decade, and their continued use in their original and translated forms. These measures include clinical, neuropsychological, neuropathological and behavioral assessments of AD, and also assessment of family history and parkinsonism in AD. An approach to evaluating neuroimages did not meet the standards desired. Further evaluations which could not be completed because of lack of funding (but where some materials are available), include evaluation of very severe AD, and of service use and need by patient and caregiver. The information that was developed in the U.S. and abroad permits standardized assessment of AD in clinical practice, facilitates epidemiological studies, and provides information valuable for individual and public health planning. CERAD materials and data remain available for those wishing to use them. KeywordsConsortium to Establish a Registry for Alzheimer's Disease; CERAD; Alzheimer's disease; clinical assessment; neuropsychological assessment; neuropathological assessment; norms; prevalence; incidence BackgroundDementing disorders have long been recognized, 1 with the identification of Alzheimer's disease (AD) typically dated back to Alzheimer's century-old paper. 2 Although considerable attention has been paid to Alzheimer's disease and substantial progress has been made in identifying its characteristics, nevertheless much remains unclear. As diagnostic procedures improve, the complexities of this disease become more apparent, and the threat it imposes becomes increasingly evident. In the population 65 years of age and older, both the incidence and prevalence of this disorder double every succeeding five years, 3 with estimated prevalence as high as 40% among those over the age of 85. AD, not recognized as a leading cause of death in 1980, was recognized as the fifth leading cause of death in 2003 among persons 65 years of age and older. 4 There is presently no cure and inadequate amelioration for this condition. It can not only strip personality and capability, but is demanding on family members, seriously disrupting their lives and their work. It is expensive for the long term care system, where about half of the residents may suffer from dementia, a substantial proportion of whom can no longer afford their own care. Although people are now reaching their older years in better health, 5,6 it remains to be seen whether there will be a decrease in the incidence of AD. Currently the fastest growing element of the population is among those 85 years of age and older, the age group where the incidence of AD is greatest.A major step in the management of a disease lies in accurate diagnosis. Relevant to current work, clinical diagnostic criteria for dementia and AD were specified about 25 years ago, and the...

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Section: Main Uses and Findingsmentioning

confidence: 99%

Consortium to Establish a Registry for Alzheimer's Disease (CERAD): The first twenty years

Fillenbaum

Belle

Morris

et al. 2008

Alzheimer's & Dementia

384

274

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“…Six words—butter, arm, letter, queen, ticket and grass—were taken from the original CERAD battery English language list (Guruje et al ., 1995). Pole, shore, cabin and engine were replaced with corner, stone, book and stick, which were deemed more cross‐culturally applicable (Prince et al ., 2003). In the learning phase, the list is read out to the participant from a green card, who is then asked to recall straight away the words that they remember.…”

Section: Methodsmentioning

confidence: 99%

“…If the subject was receiving care, the primary caregiver was considered as a reliable informant. The 26 items from the interview seek for evidence of cognitive and functional decline (Nath et al ., 1993; Hendrie et al ., 1995; Prince et al ., 2003). The response to each item is weighted, and for the purpose of this study, a summative score (CSI'D' RELSCORE) of more than 2 was considered as indicative of cognitive decline resulting in ‘functional impairment’.…”

Section: Methodsmentioning

confidence: 99%

“…This is suitable for use in people with little or no education (Prince et al ., 2003). The 10/66 battery of cognitive tests comprises the Community Screening Instrument for Dementia (CSI'D') incorporating the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) animal naming verbal fluency (VF) task, the modified CERAD 10 word list learning task with delayed recall and an informant interview for evidence of cognitive and functional decline (Prince et al ., 2003; Prince et al ., 2007). In the 10/66 pilot studies, the CSI'D', informant interview and the modified CERAD 10 word list learning task were independently able to predict the diagnosis of dementia (Prince et al ., 2003).…”

Section: Introductionmentioning

confidence: 99%

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Cognitive function and disability in late life: an ecological validation of the 10/66 battery of cognitive tests among community‐dwelling older adults in South India

Krishna

Beulah

Jones

et al. 2015

Int J Geriat Psychiatry

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BackgroundThe 10/66 Dementia Research Group developed and validated a culture and education fair battery of cognitive tests for diagnosis of dementia in population‐based studies in low‐income and middle‐income countries including India.AimsThis study examined the association between individual domains of the 10/66 battery of cognitive tests and ‘disability’ and ‘functional impairment’ in community‐dwelling older adults in South India.MethodsOne hundred twenty‐nine adults aged 60–90 years residing in Karunapura, in the city of Mysore, were interviewed in their own homes. Cognitive functioning was measured by administering the 10/66 battery of cognitive tests that composes of Community Screening Instrument for Dementia (CSI'D' COGSCORE), verbal fluency (VF) and word list memory recall (WLMR). A reliable informant was interviewed to ascertain if the subject's cognitive problems have resulted in functional impairment. Disability was measured by WHO Disability Schedule‐II (DAS).ResultsThe women had significantly lower CSI'D' COGSCORE score when compared with men (p = 0.002). The presence of ‘functional impairment’ resulting from cognitive decline was significantly associated with lower scores on VF (p = 0.03), WLMR (p = 0.03) and CSI'D' COGSCOREs (p < 0.01). There was a significant inverse association between WHO DAS II score and WLMR (p = 0.004), VF (0.006) and CSI'D' COGSCORE scores (p ≤ 0.001) even after adjusting for self‐reported ischaemic heart disease, stroke, chronic obstructive airway disease, hypertension and diabetes.ConclusionsLower scores on individual domains of the 10/66 battery of cognitive tests are associated with higher levels of disability and functional impairment in community‐dwelling older adults. These culture and education fair tests are suitable for use in population‐based research in India. Copyright © 2015 John Wiley & Sons, Ltd.

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“…This means that assessment measures developed for specific cultural environments must go under a crosscultural validation before its use for different populations. 16 In Brazil, national household surveys including those 15 years of age and older reveal a consistent increase of drug consumption. 3,4 In the First Household Survey, 4 19.4% of surveyed Brazilians reported they have already used any illicit drugs; this number was of 22.8% in the Second Household Survey.…”

Section: Introductionmentioning

confidence: 99%

Psychometric properties of the Brazilian version of the Personal Experience Screening Questionnaire

Fidalgo

Silveira

Winters

et al. 2016

Rev. Assoc. Med. Bras.

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Summary Introduction: The Personal Experience Screening Questionnaire (PESQ) is an instrument devised for assessing the magnitude of drug misuse among adolescents. However, its psychometric properties have not been evaluated in adolescent samples outside the United States. Objective: To assess the internal reliability and validity of the Brazilian version of the PESQ. Method: A cross-sectional study was carried out with 84 adolescents from a clinical sample and a community-based sample. All of them answered the PESQ. Results: Among adolescents from the community, the PESQ problem severity index, which can vary from 18 to 72, was 26.48±9.28, whereas the clinical sample scored 42.89±10.02 (p<0.001). Cronbach's alpha was 0.91. Factor analysis resulted in a four-factor solution. Furthermore, both samples also had different mean scores for the other distinct content areas measured by the instrument. Conclusion: Evidence to support the reliability and validity of the Brazilian version of the Personal Experience Questionnaire was found.

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Dementia diagnosis in developing countries: a cross-cultural validation study

Cited by 507 publications

References 27 publications

Consortium to Establish a Registry for Alzheimer's Disease (CERAD): The first twenty years

Consortium to Establish a Registry for Alzheimer's Disease (CERAD): The first twenty years

Cognitive function and disability in late life: an ecological validation of the 10/66 battery of cognitive tests among community‐dwelling older adults in South India

Psychometric properties of the Brazilian version of the Personal Experience Screening Questionnaire

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