Dementia Patients Are More Sedentary and Less Physically Active than Age- and Sex-Matched Cognitively Healthy Older Adults

Hartman, Yvonne; Karssemeijer, Esther G.A.; Diepen, Lisanne A M van; Rikkert, Marcel G M Olde; Thijssen, Dick H. J.

doi:10.1159/000491995

Cited by 87 publications

(82 citation statements)

References 39 publications

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“…Indeed, there is strong epidemiological evidence suggesting a linkage of higher midlife physical activity levels and reduced AD risk later in life. Likewise, it is well documented that older adults with AD are less physically active relative to age-and sex-matched, cognitively healthy older adults [23,24]. Hence, it is likely that reduced CRF parameters in older adults with AD are at least partially attributable to reduced habitual physical activity.…”

Section: Discussionmentioning

confidence: 99%

Establishing Reference Cardiorespiratory Fitness Parameters in Alzheimer’s Disease

Salisbury

2020

Sports Med Int Open

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Evidence is growing for aerobic exercise training as a viable means to attenuate cognitive losses associated with Alzheimer’s disease. The mechanism of action for aerobic exercise’s cognitive benefits is likely enhanced cardiorespiratory fitness and its response to incremental aerobic exercise have been incompletely evaluated in Alzheimer’s disease. The aim of this analysis was to establish cardiorespiratory fitness reference values in older adults with mild to moderate Alzheimer’s disease using a cardiopulmonary graded exercise testing. Ninety-seven community-dwelling older adults with mild to moderate Alzheimer’s disease underwent a symptom limited cardiopulmonary graded exercise test on a cycle ergometer. Differences between sexes and between Alzheimer’s disease participants with and without diagnosis of cardiovascular diseases were assessed by independent T-tests. Peak oxygen consumption was 10–20% lower than those achieved by similar clinical populations on treadmill tests. As expected, males produced significantly higher peak oxygen consumption compared to females (p =0 .02). However, the presence of concurrent cardiovascular disease did not result in statistically significant lower peak oxygen consumption compared to those without cardiovascular disease. These data provide a frame of reference for metabolic, cardiovascular, and ventilatory function during cardiopulmonary graded exercise testing performed on cycle ergometer in older adults with mild to moderate Alzheimer’s disease.

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Section: Discussionmentioning

confidence: 99%

Establishing Reference Cardiorespiratory Fitness Parameters in Alzheimer’s Disease

Salisbury

2020

Sports Med Int Open

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“…A technological limitation of the current study is the manual detection of body motion used. Preferably, an automatic detection method, such as a small wearable sensor like an accelerograph [32,33], would be used.…”

Section: Discussionmentioning

confidence: 99%

Elderly Body Movement Alteration at 2nd Experience of Digital Art Installation with Cognitive and Motivation Scores

Tao

Sato

Matsuda

et al. 2020

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The prevalence of advanced medical treatment has led to global population aging, resulting in increased numbers of dementia patients. One of the most intractable symptoms of dementia is apathy, or lack of interest and enthusiasm, which can accompany memory and cognitive deterioration. Development of a novel method to ameliorate apathy is desirable. In this feasibility trial, we propose a series of digital art installations as a candidate dementia intervention approach. Seven, three-minute scenes of digital images and sounds were presented to visitors either passively or in response to their reactions (motion and sound). We evaluated the potential of this application as an intervention against apathy in an elderly living home. We collected the dementia global standard Mini-Mental State Examination (MMSE) and questionnaire scores of sensory pleasure and motivation along with behavioral motion data in twenty participants. We further compared responses between the first and second experiences in the thirteen participants that were present for both days. Overall, we found a significant increase in participants’ motivation. In these subjects, head and right hand motion increased over different scenes and MMSE degrees, but was most significant during passive scenes. Despite a small number of subjects and limited evaluations, this new digital art technology holds promise as an apathy intervention in the elderly and can be improved with use of wearable motion sensors.

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“…Cognitive status is considered a predictive factor for healthy life span among older adults-especially in terms of physical activity and walking level [23][24][25]. Matsueda et al [24] reported a significant relationship between walking level and cognitive status evaluated by the MMSE among patients with hip fracture: Significant differences were observed in mean MMSE by walking status among people in their 80s (dependent walking status: 5.9 points, partially dependent walking status: 16.5 points, independent walking status: 23.7; p < 0.0001).…”

Section: Discussionmentioning

confidence: 99%

Reference Values and Correlations for Multiple Physical Performance Measures: A Cross-Sectional Study among Independently Mobile Older Men in Japan

Ishii¹,

Noguchi²,

Sato³

et al. 2020

IJERPH

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Purpose: Japan is one of few countries with a male life expectancy over 80 years. The gap between the healthy life span and the total life expectancy is large, highlighting the importance of maintaining physical performance. The present study aims to establish reference values for multiple physical performance measures among high-functioning oldest-old Japanese men and to investigate the correlations among these measurements to understand how these variables are related. Methods: This study was conducted with 120 Japanese males aged 80 years or older who were able to walk independently. Seven measures of physical performance were assessed: handgrip strength, quadriceps strength, static balance ability (one-legged stance), dynamic balance ability (Functional Reach Test; FRT), walking ability (5-m walking time test), combined movement ability (Timed Up & Go test), and bone quality. Cognitive function was also measured (Mini-Mental State Examination; MMSE). Results: Specific reference values are reported for each physical performance measurement explored in this study. Only six participants were classified as cognitively impaired, and 16 had mild cognitive impairment. There were significant correlations of varying levels among all of the measures of physical performance. Age was significantly correlated with all performance measures except FRT, and there was no correlation between age and MMSE. MMSE was weakly correlated with FRT and unrelated to the other performance measures. Conclusions: The reference ranges can be used by older men who have not yet reached 80 years and their health care providers as physical performance targets to facilitate the maintenance of independent mobility in later life.

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Dementia Patients Are More Sedentary and Less Physically Active than Age- and Sex-Matched Cognitively Healthy Older Adults

Cited by 87 publications

References 39 publications

Establishing Reference Cardiorespiratory Fitness Parameters in Alzheimer’s Disease

Establishing Reference Cardiorespiratory Fitness Parameters in Alzheimer’s Disease

Elderly Body Movement Alteration at 2nd Experience of Digital Art Installation with Cognitive and Motivation Scores

Reference Values and Correlations for Multiple Physical Performance Measures: A Cross-Sectional Study among Independently Mobile Older Men in Japan

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