We demonstrate a tunable bandpass optical filter based on a tapered optical fiber (TOF) touched by a hemispherical microfiber tip (MFT). Other than the interference and selective material absorption effects, the filter relies on the controllable and wavelength-dependent mode–mode interactions in TOF. Experimentally, a large range of tunability is realized by controlling the position of the MFT in contact with the TOF for various TOF radii, and two distinct bandpass filter mechanisms are demonstrated. The center wavelength of the bandpass filter can be tuned from 890 nm to 1000 nm, while the FWHM bandwidth can be tuned from 110 nm to 240 nm when the MFT touches the TOF in the radius range from 160 nm to 390 nm. The distinction ratio can reach 28 ± 3 dB experimentally. The combined TOF-MFT is an in-line tunable bandpass optical filter that has great application potential in optical networks and spectroscopy, and the principle could also be generalized to other integrated photonic devices.