Dendritic macromolecules containing several types of functional groups

Abstract

Dendritic macromolecules containing several types of functional groups were successfully synthesized through divergent method. Poly(ethylene glycol) was functionalized using cyanuric chloride and it was reacted with p‐toluidine at room temperature and a macromolecule containing chloride and methyl functional groups (PEG‐Cl2‐Me2) was obtained. Substitution of chloride functional groups of PEG‐Cl2‐Me2 by hydroxyl functional groups led to a macromolecule containing methyl and hydroxyl functional groups (PEG‐Me2‐OH4). Hydroxyl functional groups of PEG‐Me2‐OH4 were reacted with cyanuric chloride and PEG‐Me2‐Cl8 was obtained. Finally, PEG‐Me2‐Cl8 was reacted with p‐aminophenol at room temperature and a macromolecule containing methyl, hydroxyl, and chloride functional groups (PEG‐Me2‐(PhOH)4‐Cl4) was obtained. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2010

Linear-dendritic copolymers/indoxacarb supramolecular systems: biodegradable and efficient nano-pesticides

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“…8 Amphiphilic linear-dendritic block copolymers possess properties that allow self-assembly into different shapes and have the capacity to form complex supramolecular architectures. [9][10][11][12] Applying new molecules or materials to the formulation of pesticides to produce nanopesticides that are biodegradable and safe for non-target organisms is an expanding research area. 13 Citric acid (CA) and poly(ethylene glycol) (PEG) are the components of the biocompatible poly(citric acid)-poly(ethylene glycol)-poly-(citric acid) (PCA-PEG-PCA) ABA type linear-dendritic block copolymers used in this study.…”

Dendrimers as Novel Polymeric Material: A Review on Its Synthesis, Characterization and Their Applications

“…Thus, growth of the dendrimer is from the central core to the periphery. In other words, the dendrimer is induced to grow from the core outward [35][36][37][38][39][40] (see Fig. 2).…”

Polyrotaxane/gold nanoparticle hybrid nanomaterials as anticancer drug delivery systems

“…39 Functionalization of polyethylene glycol PEG (M n ¼ 1000) was functionalized via the end triazine groups according to the reported procedure in the literature. [40][41][42] Typically, a solution of PEG (9 g, 9 mmol) and sodium hydroxide (0.64 g, 16 mmol) in 5 ml water was added dropwise to a solution of cyanuric chloride (13 g, 7 mmol) in 150 ml dichloromethane and stirred at 0-40 C for 1 h and then refluxed for 6 h. The mixture was then filtered and the solvent was evaporated and the obtained solid compound was dissolved in diethyl ether. The solution was then filtered and the final product was precipitated in an ice bath as a colorless compound.…”