Dental adhesives and strategies for displacement of water/solvents from collagen fibrils

Abstract

Objectives-To evaluate the influence of temperature of evaporation in adhesive systems with different solvents on the apparent modulus of elasticity and mass change of macro-hybrid layers modified by proanthocyanidins (PACs). Methods-Adhesive resin beams (A) from Single Bond Plus (SB), Excite (EX) and OneStep Plus (OS) were prepared after solvent evaporation at 23°C or 40°C (n=12). Macro-hybrid layers (M) (n= 12) were prepared using demineralized dentin beams sectioned from extracted human third molars. The demineralized dentin specimens were infiltrated with each one of the three adhesive systems at 23°C or 40°C; with or without prior dentin treatment with PACs for 10 minutes. The apparent modulus of elasticity (E) and mass change (W mc %) of adhesives beams and resin-infiltrated specimens were assessed in dry and wet conditions after immersion in water (24 h, 1, 3 and 6 months). The E was statistically analyzed by Tukey-Kramer test and the W mc % by Kruskal Wallis, and Dunn (α=0.05).Results-Solvent evaporation at 40 °C resulted in higher E values for adhesive resin beams at all storage conditions, regardless of the adhesive system (p < 0.05). Increased Mass Loss (3 months: −0.01%; 6 months: −0.05%) was observed in One Step resin beams (p ≤ 0.05). In the macro hybrid layer models the pretreatment with PACs along with solvent evaporation at 40 °C increased E and decreased the W mc % (3 months: −2.5; 6 months: 2.75%) for adhesives evaluated over time (p < 0.05). No significant differences in Ratio (resin/dentin) were found for the macro hybrid layers (p> 0.05). Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. HHS Public Access Author Manuscript Author ManuscriptAuthor Manuscript Author ManuscriptSignificance-Improved solvent evaporation at higher temperature, and increased collagen cross-linking induced by PACs, enhanced the mechanical properties resulting in highly stable macro-hybrid layers over 6 months storage.

Dimeric Proanthocyanidins on the Stability of Dentin and Adhesive Biointerfaces

“…Model. Macro-hybrid layers (Chiaraputt et al 2008;Matuda et al 2016) were prepared, and the degree of conversion (Cadenaro et al 2009;Malacarne-Zanon et al 2009;Parthasarathy et al 2012) of the adhesive system at the hybrid layer was assessed, as described in the Appendix. Briefly, dentin specimens were demineralized and treated for 1 h with biomodification primers (DIMER G , DIMER NG , and e-GSE) and control (Hepes).…”

“…Adhesion protocols in dentistry rely on the formation of micromechanical retention of a dental methacrylate resin infiltrate to enamel and dentin. In the case of dentin, effective infiltration of resin monomers within the dentin extracellular matrix (ECM), biostability of the underlying tissue, and low permeability of the polymerized resin system are key for the success of adhesive restorations (Navarra et al 2012;Matuda et al 2016;Silva Sousa et al 2016;Cadenaro et al 2019).…”

Alternativas para minimizar a degradação da interface adesiva de restaurações dentais: revisão da literatura

“…A utilização de jato de ar aquecido 29 para volatilização do sistema adesivo, devido à elevação da temperatura do material 30,39 aumenta consideravelmente a evaporação dos solventes, 31 melhorando as propriedades físico-mecânicas 41 e reforçando a camada híbrida. 40 Além disso, a elevação na temperatura por meio do pré-aquecimento dos sistemas adesivos pode melhorar a performance dos adesivos. 30 Uma maneira de desidratar a dentina sem provocar o colapso das fibrilas de colágeno expostas após o condicionamento ácido é tratar a matriz dentinária com solventes anidros que sejam capazes de manter tal substrato expandido e ao mesmo tempo livre de água; 14,41 apto a ser infiltrado pelos monômeros resinosos do sistema de união.…”

“…É necessária efetiva volatilização da água e de solventes antes da polimerização, para que ocorra o processo de hibridização com qualidade 5,15,38 . A utilização de jato de ar aquecido 29 para volatilização de solventes do sistema adesivo tem sido objeto de estudos com resultados promissores devido à elevação da temperatura do material 39 , elevando consideravelmente a evaporação dos solventes 31 , aumentando as propriedades físico-mecânicas 39 e melhorando a estabilidade da camada híbrida formada, pela formação de uma camada adesiva mais homogênea e resistente 40 .…”

Adhesive Systems Used in Indirect Restorations Cementation: Review of the Literature

“…Another important factor is to consider the components of the adhesive systems and to know their affinity for water [48]. It has not been possible to determine if the free water is completely replaced by the resinous component, however in this situation the solvents can have direct influence, since the monomers are dissolved in organic solvents to facilitate the diffusion of the monomer in the collagen matrix and allow the elimination of water during evaporation of the solvent [49]. For all of the above, it was considered relevant to carry out a systematic review of the adhesive systems used in the cementing of indirect restorations, based on the available scientific evidence and analyzing characteristics of the bond strength of these systems to the dental tissues, which may help the clinician in his daily practice to base decisions on.…”