Dental genetics in Brazil: Where we are

Casado, Priscila Ladeira; Quinelato, Valquiria; Cataldo, Patricia; Guerra, Ricardo Luz Leitão; Campello, Marco; Bonato, Letícia Ladeira; Aguiar, Telma Regina da Silva

doi:10.1002/mgg3.457

Cited by 4 publications

(5 citation statements)

References 76 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Dental research in the field of genetics has been introduced in universities as a vital part of developing a thriving and strong educational system in its three pillars-Education, Research, and Extension-and studies are growing as new faculties of dentistry incorporate and mature a solid research profile in their educational programs [28], opening up a diagnostic possibility and possible future therapeutic proposals.…”

Section: Discussionmentioning

confidence: 99%

Epidermal Growth Factor Is Associated with Loss of Mucosae Sealing and Peri-Implant Mucositis: A Pilot Study

et al. 2021

Self Cite

View full text Add to dashboard Cite

This study aimed to evaluate the correlation between epidermal growth factor (EGF) and receptor (EGFR) levels in different clinical stages of dental implant rehabilitation and trace mucositis development’s biological profile. Thirty-six participants from the Specialization in Implant Dentistry, Universidade Federal Fluminense, Brazil, were included in the study and underwent sample collection: inside the alveolar socket, immediately before implant placement (Group 1, n = 10); at the peri-implant crevicular fluid (PICF) during reopening (Group 2, n = 10); PICF from healthy peri-implant in function (Group 3, n = 8); and PICF from mucositis sites (Group 4, n = 18). Quantitative polymerase chain reaction (PCR) evaluated EGF/EGFR gene expression using the SYBR Green Master Mix detection system. The results showed that EGF expression in the peri-implant crevicular fluid was statistically different. There was a higher EGF expression for group C (peri-implant health) (p = 0.04) than for the other groups. Regarding EGFR, there was no statistical difference among the groups (p = 0.56). It was concluded that low levels of EGF gene expression in the peri-implant crevicular fluid are related to the development of peri-implant mucositis and the absence of mucosae sealing. There was no correlation between EGFR gene expression with health or mucositis.

show abstract

Section: Discussionmentioning

confidence: 99%

Epidermal Growth Factor Is Associated with Loss of Mucosae Sealing and Peri-Implant Mucositis: A Pilot Study

et al. 2021

Self Cite

View full text Add to dashboard Cite

show abstract

“…A importância da Odontologia na assistência a indivíduos com defeitos congênitos O cirurgião-dentista deve ter o conhecimento de conceitos básicos de genética humana e clínica 64,65 . Os cursos de graduação em geral deixam de considerar a genética em sua prática clínica odontológica 66 , porém os conceitos e princípios da genética deveriam passar de um conteúdo teórico para um conhecimento que é aplicado no cuidado de pacientes 56 . Compreender os aspectos genéticos das doenças e gerar novas abordagens para prevenir, diagnosticar e manejar doenças e síndromes criaram novas necessidades para a ciência básica e educação clínica em odontologia.…”

Section: Discussionunclassified

“…Compreender os aspectos genéticos das doenças e gerar novas abordagens para prevenir, diagnosticar e manejar doenças e síndromes criaram novas necessidades para a ciência básica e educação clínica em odontologia. Implicações sociais, éticas e legais novas e desafiadoras estão associadas ao uso de informações genéticas no tratamento e prevenção de doenças 56,66 .…”

Section: Discussionunclassified

A importância da Odontologia na assistência a indivíduos com defeitos congênitos

Maria

Oliveira

Schüler‐Faccini

2021

R. Fac. Odontol. Porto Alegre

View full text Add to dashboard Cite

Introduction: Birth defects are structural or functional changes that occur during intrauterine life. The dentist must recognize the craniofacial defects, complement the phenotypic characterization and manage them within a multidisciplinary team. The present review aims to assist the dentist to diagnose these findings and present syndromic conditions typically associated with craniofacial malformations Literature Review: Craniofacial manifestations of birth defects are conditions that must be recognized by dentists, as they are frequently present in their daily practices, and this professional may be the first to identify such findings. The main syndromic clinical pictures typically associated with micrognathia, oral clefts and skeletal dysplasias with craniofacial manifestation are presented, pointing out their clinical and genetic features. Discussion: The dentist must perform a detailed anamnesis including family history, as well as should recognize both clinical and radiographically the dysmorphisms, observing the patient systemically. Conclusion: Dentistry professionals should receive theoretical-practical training for the diagnosis, treatment and surveillance of individuals with congenital defects, either in individual assessment or as part of a multiprofessional team.

show abstract

“…In a survey from Brazil, 5.3% of dentists reported treatment of COVID-19 patients. 15 Although an explanation for the higher treatment of COVID -19 patients in South Africa cannot be readily found, the higher number of dentist per inhabitants in Brazil is twice as high as recommended by the WHO (1:753), 16 which is extraordinarily higher than the dentist to population ratio of 1:8,900 in South Africa. 17 In this survey, only 1.1% of respondents attributed COVID -19 infections of dental practitioners and their staff to dental practices, which is low compared to the frequency of treatment of COVID-19 positive patients (13.9%).…”

Section: Methodsmentioning

confidence: 96%

An overview of COVID-19 infection in dental practices - a questionnaire survey

Gluckman

Pontes²,

Troelzsch

et al. 2021

S. Afr. dent. j.

View full text Add to dashboard Cite

Dental nurses and practitioners are at high risk of exposure to COVID-19 due to physical proximity and exposure to body fluids during treatment. Dental practices have implemented multiple protective protocols to decrease COVID-19 transmission; however, it is difficult to evaluate how effective these measures are, as there is limited data on COVID-19 in dental practices. To evaluate COVID-19 infection rates among dentists, dental staff, and patients in different countries through an online survey, with a primary focus on South Africa (SA). Cross-sectional online survey. One hundred fifty-four participants from 52 countries answered the survey, 48.6% (n=561) from SA. COVID-19 infections were reported in 18.2% (n=210) of dental practices. Only 1.1% regarded the practice as the source of infection for dentists and staff who got infected. In total, 13.9% (n=160) treated COVID-19 patients. SA presented a higher infection rate (19% vs 13%, p=0.04) and more frequent treatment of COVID-19 patients than the other countries combined (17% vs 11%, p=0.006). These findings support the need to maintain strict infection control measures to decrease transmission of SARSCoV-2 during the delivery of oral care.

show abstract

Dental genetics in Brazil: Where we are

Cited by 4 publications

References 76 publications

Epidermal Growth Factor Is Associated with Loss of Mucosae Sealing and Peri-Implant Mucositis: A Pilot Study

Epidermal Growth Factor Is Associated with Loss of Mucosae Sealing and Peri-Implant Mucositis: A Pilot Study

A importância da Odontologia na assistência a indivíduos com defeitos congênitos

An overview of COVID-19 infection in dental practices - a questionnaire survey

Contact Info

Product

Resources

About