Dental Metal Allergy in Patients With Oral, Cutaneous, and Genital Lichenoid Reactions

Scalf, Leigh Ann; Fowler, Joseph F.; Morgan, Kelli W.; Looney, Stephen W.

doi:10.1097/01206501-200109000-00003

Cited by 9 publications

(12 citation statements)

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“…The association between oral lichenoid reactions and the use of mercury and gold in dental amalgams is well established (1). Contact stomatitis from nickel in dental prostheses has also been reported, and there have been isolated reports of oral lichenoid reactions to other metals such as zinc (2).…”

Section: Commentmentioning

confidence: 99%

“…However, we are unaware of any report of localized lichenoid reactions to chromate/cobalt confirmed by patch testing. A recent review of patch test results in patients with lichen planus and lichenoid reactions highlighted an increased rate of sensitization to dental metals compared with patients undergoing routine patch tests (1). Significant increases in the rate of allergy to gold and chromates were also identified.…”

Section: Commentmentioning

confidence: 99%

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Oral lichenoid reaction due to chromate/cobalt in dental prosthesis

2003

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Section: Commentmentioning

confidence: 99%

Section: Commentmentioning

confidence: 99%

Oral lichenoid reaction due to chromate/cobalt in dental prosthesis

2003

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“…In such mixed cases (9, 19–25), gold allergy has been demonstrated in 7–54% (mean 20%). Among patients with a non‐specific stomatitis, gold allergy was found in 1–13% (23, 26, 27), with a lichenoid reaction in 9–30% (28–32). Contact allergy to gold as well as to mercury is frequent in connection with lichenoid reactions in the oral cavity (20, 28, 29).…”

Section: Gold Allergy In Relationship To Dental Goldmentioning

confidence: 99%

Dental gold alloys and contact allergy

Möller

2002

Contact Dermatitis

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Contact allergy to gold as demonstrated by patch testing is very common among patients with eczematous disease and seems to be even more frequent among patients with complaints from the oral cavity. There is a positive correlation between gold allergy and the presence of dental gold. Gold allergy is often found in patients with non-specific stomatitides as well as in those with lichenoid reactions or with only subjective symptoms from the oral cavity. The therapeutic effect of substituting other dental materials for gold alloys is conspicuous in casuistic reports but less impressive in larger patient materials. The amount of dental gold is correlated qualitatively and quantitatively to the blood level of gold and the effects if any of circulating blood gold are unknown. There is clearly a need for prospective studies in the field and gold sodium thiosulfate is considered an important item in the dental series for patch testing.Key words: contact allergy; dental gold; gold alloy; lichenoid reaction, oral disease; stomatitis. C Blackwell Munksgaard, 2002. Accepted for publication 12 July 2002 DefinitionsThe term dental gold covers alloys containing gold as a component and included in the ISO standards (1, 2). Allergy to gold alloys implies contact allergy, i.e. the T-cell mediated, immunological state which is not expressed as a clinical reaction until a renewed contact with the hapten. A prerequisite for the induction as well as the elicitation of this allergy is dissolution and ionization of the metal followed by penetration of the hapten into the skin or mucous membrane. Dissolution of metallic gold is notoriously difficult but the process is facilitated by the presence of other metals in the alloy -the lower carat, the greater solubility of the gold (3) -but also by metals in the neighbourhood, e.g. amalgam through galvanism (4). Furthermore, dissolution and ionization are promoted by a high pH, an oxidative environment and the presence of amino acids, particularly sulfur-containing ones (3, 5). Diagnosis

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“…Metals are thought to cause various types of allergic reactions (including dermatitis, lichen planus, palmoplantar pustulosis, asthma and rhinitis) [1–6], and even to cause carcinomas [4]. Alloys containing Ni are widely used in our environment and in medicine, exposing us to Ni through a variety of routes.…”

Section: Introductionmentioning

confidence: 99%

Lipopolysaccharide promotes and augments metal allergies in mice, dependent on innate immunity and histidine decarboxylase

Sato

Kinbara

Kuroishi

et al. 2007

Clin Experimental Allergy

143

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These results indicate that in mice, LPS is a very important inducer of metal allergies, and potently promotes them (dependent on both innate immunity and HDC induction in cells other than mast cells). We discussed the idea that the bacterial environment is important for the establishment of metal allergies and for their provocation, and that the current thinking (including the contribution of T cells) should be reappraised in future studies.

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Dental Metal Allergy in Patients With Oral, Cutaneous, and Genital Lichenoid Reactions

Cited by 9 publications

References 0 publications

Oral lichenoid reaction due to chromate/cobalt in dental prosthesis

Oral lichenoid reaction due to chromate/cobalt in dental prosthesis

Dental gold alloys and contact allergy

Lipopolysaccharide promotes and augments metal allergies in mice, dependent on innate immunity and histidine decarboxylase

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