Objectives
Since the SARS-CoV-2 outbreak in 2019, special safety protocols were introduced in dentistry. Dental professions were established mostly at risk of gaining the virus because of aerosol generating procedures used. This preliminary study, starts the cycle of the laboratory protocols describing the quality and efficacy of laboratory tests in the SARS-CoV-2 IgG detection in the serum of asymptomatic dental personnel during the last quarter of 2020.
Methods
IgG levels were measured with the use of semi-quantitative enzyme-linked immunosorbent assay (ELISA) in vitro diagnostic (IVD) kit in the serum of study group that consisted of 127 employees of the dental clinic, divided into three subgroups: SUB1: dentists (n=67), SUB2: dental assistants, dental hygienists, nurses, laboratory workers (n=40), SUB3: administrative workers (n=20). Pearson analysis of results from the questionnaires attached to the study protocol were provided, to assure the results compare to the subjects impressions about their general health.
Results
Positive ELISA IgG results were received in 6% (4 subjects) of the SUB1 group, 7.50% (3 subjects) from the SUB2 group, and 5% from the SUB3 group. Percentage of subjects without work interruption from the beginning of pandemics involved 54% of dentists and 60% of chairside assistants.
Conclusion
Serum IgG prevalence with the use of semi-quantitative test was low, and further research on the biobanked samples has to be followed, to conclude the levels of IgG with quantitative methods and/or to evaluate the presence of neutralizing antibodies in dental personnel. Since the low representation of seropositivity studies in this group, it will be crucial to confirm the risk of COVID-19 transmission in dental offices.