Dependence of Frequency and Magnetic Field on Self-Heating Characteristics of NiFe$_2$O$_4$Nanoparticles for Hyperthermia

Bae, Seongtae; Lee, Sang Won; Takemura, Yasushi; Yamashita, E.; Kunisaki, J.; Zürn, S.; Kim, Chul Sung

doi:10.1109/tmag.2006.879617

Cited by 45 publications

(19 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…1,2 SAR can be estimated by calorimetric methods as SAR = ͑1 / m͒C͑⌬T / ⌬t͒, where m is the mass of the dissipating material, C the heat capacity of the whole sample, and ⌬T the sample temperature increase during the ac-field application interval ⌬t. Current SAR installations reported in literature 8,10,[14][15][16] consist of an ac magnetic field generator, a sample space delimited by an isolating material, temperature sensors, and a data acquisition system. These setups do not provide adiabatic conditions, since heat losses ͑conduction, radiation, and convection͒ are not minimized.…”

mentioning

confidence: 99%

Accurate measurement of the specific absorption rate using a suitable adiabatic magnetothermal setup

Natividad

Castro

Mediano

2008

Applied Physics Letters

View full text Add to dashboard Cite

Accurate measurements of the specific absorption rate ͑SAR͒ of solids and fluids were obtained by a calorimetric method, using a special-purpose setup working under adiabatic conditions. Unlike in current nonadiabatic setups, the weak heat exchange with the surroundings allowed a straightforward determination of temperature increments, avoiding the usual initial-time approximations. The measurements performed on a commercial magnetite aqueous ferrofluid revealed a good reproducibility ͑4%͒. Also, the measurements on a copper sample allowed comparison between experimental and theoretical values: adiabatic conditions gave SAR values only 3% higher than the theoretical ones, while the typical nonadiabatic method underestimated SAR by 21%. © 2008 American Institute of Physics. ͓DOI: 10.1063/1.2891084͔ Magnetic-fluid hyperthermia ͑MFH͒ for cancer treatment is currently attracting considerable scientific and technical work. 1-3 The use of nanoscale heaters to destroy cancerous tissue allows overcoming certain problems arising from other hyperthermia therapies, 4 such as damage of healthy tissue, temperature miscontrol, and use of hazardous alternating magnetic fields out of the biological range.The heating efficiency of the fluids is quantified by the specific absorption rate ͑SAR͒, defined as the thermal power per unit mass dissipated by the active material in the presence of an alternating magnetic field. SAR highly depends on field parameters and on material properties, since different heating mechanisms can be involved. 5,6 So accurate measurements are necessary for the studies on correlation between the SAR and material properties, 7-11 simulations of temperature distributions in tissues or phantoms, 12,13 and the optimization of hyperthermia therapies. 1,2 SAR can be estimated by calorimetric methods as SAR = ͑1 / m͒C͑⌬T / ⌬t͒, where m is the mass of the dissipating material, C the heat capacity of the whole sample, and ⌬T the sample temperature increase during the ac-field application interval ⌬t. Current SAR installations reported in literature 8,10,14-16 consist of an ac magnetic field generator, a sample space delimited by an isolating material, temperature sensors, and a data acquisition system. These setups do not provide adiabatic conditions, since heat losses ͑conduction, radiation, and convection͒ are not minimized. SAR must be estimated from the temperature-versus-time exponential curve, 16 according to the expression SAR= C␤ / m, where ␤ = ͉͑dT / dt͉͒ t→0 is the initial slope. This procedure can lead to unknown errors in the determination of ␤ and, therefore, to incorrect SAR values, if the initial thermal losses are not negligible, or if there is not a homogeneous temperature distribution across the sample, facts that are not easy to infer in practice.In this letter, we report accurate SAR measurements using an adiabatic magnetothermal setup, 17 in which the sample undergoes only a weak net heat exchange with the surroundings, overcoming the previous limitations. In such conditions, the generated hea...

show abstract

mentioning

confidence: 99%

Accurate measurement of the specific absorption rate using a suitable adiabatic magnetothermal setup

Natividad

Castro

Mediano

2008

Applied Physics Letters

View full text Add to dashboard Cite

show abstract

“…So, we can consider that the majority of the nanoparticles in the sample become superparamagnetic at around 135 K. The specific absorption rate (SAR) of the sample in an alternating magnetic field was measured calorimetrically in an AC magnetic field at a frequency of 100 kHz and a magnetic field of 29.4 kA/m. Here, the value of the product between the frequency and the intensity of the AMF is 29.4 × 10 8 Am −1 s −1 , which is below the biological range for applications of magnetic hyperthermia in a small body region [23]; however, it is above the value imposed for the whole body exposure [24]. We used higher field parameters for our study, and, therefore, they are appropriate for smaller body regions.…”

Section: Resultsmentioning

confidence: 97%

Synthesis and characterization of Ni–Cu alloy nanoparticles with a tunable Curie temperature

Ferk

Stergar

Makovec

et al. 2015

Journal of Alloys and Compounds

View full text Add to dashboard Cite

“…Вследствие теплового эффекта под влиянием магнитного поля происходит деградация частиц, что приводит к снижению скорости нагрева (рис. 4, а−с), согласующемуся с данными [19].…”

Section: методикA исследованийunclassified

“…Физическая природа быстрого повышения температу-ры на начальной стадии может быть объяснена процес-сами потерь: потерями за счет гистерезиса, вихревых токов, а также неелевскими и броуновскими потеря-ми [19]. Поскольку ферриты обладают очень низкой проводимостью, вклад от потерь на вихревые токи незна-чителeн.…”

Section: результаты и обсуждениеunclassified

Исследованиe наночастиц Co-=SUB=-0.5-=/SUB=-Zn-=SUB=-0.5-=/SUB=-Fe-=SUB=-2-=/SUB=-O-=SUB=-4-=/SUB=- для магнитной гипертермии

Kamzin¹,

Nikam²,

Pawar³

2017

Физика Твердого Тела

View full text Add to dashboard Cite

Исследованы структурные характеристики, магнитные свойства и процессы магнитного нагрева в переменном магнитном поле магнитных наноразмерных частиц (МНЧ) Co 0.5 Zn 0.5 Fe 2 O 4 (CZF) с целью изучения возможностей применения их в медицинe, а именно для магнитной гипертермической терапии (нагревания частиц внешним переменным магнитным полем). МНЧ CZF получены методом соосаждения с использованием гидроксида натрия (NaOH) в качестве осаждающего агента. На основе данных, полученных с помощью электронной микроскопии в геометрии пропускания, установлено, что МНЧ CZF имеют практически сферическую форму со средним размером частиц 13 nm. Рентгеновские дифракционные и мессбауэровские исследования показали, что МНЧ CZF однофазны и их структура соответствует кубической структуре шпинели. Намагниченность насыщения Ms МНЧ CZF измерена при комнатной температуре с помощью магнитометра с вибрирующим образцом. Способность нагревания МНЧ CZF внешним переменным магнитным полем изучалась с использованием системы индукционного нагрева. Удельный коэффициент поглощения определен при приложении внешнего переменного магнитного поля в диапазоне от 167.5 до 335.2 Oe при фиксированной частоте 265 kHz. Установлено, что максимальное количество тепла (114.98 W/g) выделяется при концентрации 5 mg/l в поле напряженностью 335.2 Oe.

show abstract

Dependence of Frequency and Magnetic Field on Self-Heating Characteristics of NiFe$_2$O$_4$Nanoparticles for Hyperthermia

Cited by 45 publications

References 6 publications

Accurate measurement of the specific absorption rate using a suitable adiabatic magnetothermal setup

Accurate measurement of the specific absorption rate using a suitable adiabatic magnetothermal setup

Synthesis and characterization of Ni–Cu alloy nanoparticles with a tunable Curie temperature

Исследованиe наночастиц Co-=SUB=-0.5-=/SUB=-Zn-=SUB=-0.5-=/SUB=-Fe-=SUB=-2-=/SUB=-O-=SUB=-4-=/SUB=- для магнитной гипертермии

Contact Info

Product

Resources

About