Dependence of the response of an amperometric biosensor formed in a micro flow channel on structural and conditional parameters

Hashimoto, Minoru; Upadhyay, S. H.; Suzuki, Hiroaki

doi:10.1016/j.bios.2005.11.009

Cited by 17 publications

(9 citation statements)

References 30 publications

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“…7A) Satoh et al, 2008;Yi et al, 2012). In this case, equal splitting of the stream of solution is of great importance since the flow rate can have significant influence on the measurement (Hashimoto et al, 2006;Lamberti et al, 2012). Alternatively, multiple electrodes can be placed in the same channel (Frey et al, 2010;Parra-Cabrera et al, 2012).…”

Section: Characteristics and Performancementioning

confidence: 99%

Microfluidic enzymatic biosensing systems: A review

Mross

Pierrat

Zimmermann

et al. 2015

Biosensors and Bioelectronics

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Section: Characteristics and Performancementioning

confidence: 99%

Microfluidic enzymatic biosensing systems: A review

Mross

Pierrat

Zimmermann

et al. 2015

Biosensors and Bioelectronics

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“…Although the generated current depends on the flow rate, only a fraction of the analyte flowing in the stream is used for the corresponding electrode reaction [27]. In other words, there is enough room to improve the detection sensitivity by increasing the collection efficiency.…”

Section: Electrochemical Microsensors 21 Amperometric Sensorsmentioning

confidence: 99%

Electrochemical techniques for microfluidic applications

et al. 2008

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Electrochemical principles provide key techniques to promote the construction of bio/chemical microsystems of the next generation. There is a wealth of technology for the microfabrication of bio/chemical sensors. In addition, microfluidic transport in a network of flow channels, pH regulation, and automatic switching can be realized by electrochemical principles. Since the basic components of the devices are electrode patterns, the integration of different components is easily achieved. With these techniques, bio/chemical assays that require the exchange of solutions can be conducted on a chip. Furthermore, autonomous microanalysis systems that can carry out necessary procedures are beginning to be realized. In this article, techniques developed in our group will be comprehensively introduced.

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“…As organophosphorous compounds are inhibitors of acetylcholinesterase, amperometric biosensors based on enzymatic AChE inhibition were used. The AChE biosensor response decreases in correlation with the amount of pesticides in samples and the time of incubation, as described in many publications (1,2,4,14,34,35). in recent years, AChE has been immobilized onto various nanomaterial surfaces in order to improve the response and stability in trace pesticide detection.…”

Section: Introductionmentioning

confidence: 99%