Depression and Anxiety Disorders among Patients with Psoriasis: A Hospital-Based Case-Control Study

Abstract

Background. Psoriasis is a common, genetically determined inflammatory and proliferative disease of the skin. Psychological stress can exacerbate the disease. This study sought to investigate the depression and anxiety disorders among patients with psoriasis and control group. Method. In this hospital-based case-control study, One hundred patients with psoriasis (case) referred to the dermatology department and 100 patients with otolaryngology problems and dermatological healthy volunteers (control) who referred to the Otolaryngology Department of Bouali Sina Hospital in Sari, Iran, in 2007 were studied. Demographic characteristics were recorded. Beck Depression Inventory and Spielberger State-Trait Anxiety Scale I-II were administered to the patients in both groups. Data were analyzed using SPSS statistical software and descriptive statistical tests. Results. From One-hundred patients in each group, 44 (45%) were men. Depression score was 67% and 12% in psoriatic patients and control, respectively. The Beck depression scores of patients with psoriasis were significantly higher than scores of the control group (P < 0.05). Based on Spielberger State-Trait Anxiety Scale, anxiety was found in 45% of patients in case group and 18% of controls. Conclusion. The results revealed that psoriatic patients reported significantly higher degrees of depression and anxiety than controls. In addition, psoriatic women were more depressed than psoriatic men.

Psychiatric Morbidity and Quality of Life in Patients suffering from Psoriasis in a Tertiary Care Hospital

“…Despite the fact that depression and anxiety did not differ significantly between patients with psoriasis and healthy controls, it is noteworthy that 33.3 and 60% of the psoriatic patients scored above the cut-off score in the HADS-D and HADS-A subscale respectively, a finding, i.e., consistent with the study conducted by Korkoliakou et al, 14 which suggests that psychological morbidity is a clinically important concern in patients with psoriasis. This result was also supported by another study conducted by Golpour et al 15 The lower scores on QOL scale by cases of psoriasis compared with that of healthy controls may be due to their perceived lesions, social stigma, lack of social support, and disturbing activities of daily living due to the skin. This finding is supported by a similar study conducted by Bhosle et al 16 in which there was a negative impact on patient's health-related QOL.…”

Screening for anxiety and depression in people with psoriasis: a cross-sectional study in a tertiary referral setting

“…20,21 We were surprised that the prevalence of probable depression in our cohort (9.9%), from a tertiary centre and thus a likely "high-need" cohort, was lower than other tertiary centres. 22 We also found the prevalence of anxiety (13.1%) to be lower than previous authors in a tertiary psoriasis clinic (43%).…”

Depression, Anxiety and Stress among Saudi Arabian Dermatology Patients: Cross-sectional study

“…21 In another study, depression (67% versus 12%) and anxiety (45% versus 18%) rates were higher in psoriasis patients than a control group. 11 Kurd et al noted that the risk of being diagnosed with depression, anxiety or suicidal ideation was 39% higher in patients with psoriasis compared to healthy controls. 22 However, no relationship was seen in the current study between negative emotional states and the type of dermatological disease.…”

“…8,9 Anxiety levels and quality of life (QOL) have likewise been shown to be affected by dermatological disorders, with atopic dermatitis patients suffering from increased anxiety and a poorer QOL when compared to healthy individuals. 10,11 Although psychological symptoms are common among dermatology patients, few relevant studies on this subject have been conducted among Arab populations. At the Khartoum Hospital in Sudan, Mufaddel et al found that rates of depression and anxiety were higher among dermatology outpatients with acne, vitiligo, eczema and psoriasis compared with healthy controls.…”