Depression and cognitive deficits in geriatric schizophrenia

D'Antonio, Emily; Serper, Mark R.

doi:10.1016/j.schres.2011.10.006

Cited by 13 publications

(7 citation statements)

References 37 publications

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“…We also found that men working in a general hospital and having lower levels of education were associated with more severe psychopathological symptoms. The link between dissociation and sex has been confirmed in several studies ( 43 – 45 ), and it is generally believed that women are more likely to suffer from dissociation ( 46 ); therefore, our conclusions were inconsistent. Since there was no difference between the total scores of males and females in the ASDS scale but only in the dissociation sub-items, it may not have much practical significance.…”

Section: Discussionmentioning

confidence: 69%

Influencing Factors Associated With Mental Health Outcomes Among Dental Medical Staff in Emergency Exposed to Coronavirus Disease 2019: A Multicenter Cross-Sectional Study in China

Chen

2021

Front. Psychiatry

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Background: The epidemic infection of coronavirus disease 2019 (COVID-19) may have a profound impact on dentistry, mainly due to the mode of transmission of the pathogen, which poses a risk to almost all dental operations. Therefore, this study aimed to investigate the prevalence and influencing factors of anxiety, depression, perceived stress, and acute stress disorder among dental medical staff in emergency situations during the COVID-19 epidemic.Methods: From April 3, 2020, to April 10, 20204, a multicenter cross-sectional study was conducted among 808 first-line dental professionals at an emergency department in mainland China. A self-designed questionnaire was used to collect general demographic information. The 7-item Generalized Anxiety Disorder Scale (GAD-7), 9-item Patient Health Questionnaire (PHQ-9), 10-item Perceived Stress Scale (PSS-10), and Acute Stress Disorder Scale (ASDS) were used to assess the severity of symptoms of anxiety, depression, perceived stress, and acute stress disorder (ASD), respectively.Results: The prevalence rates of depression, anxiety, perceived pressure, and ASD among the frontline dental medical staff were 46.4, 36.3, 65.2, and 1.1%, respectively. The frontline dental medical staff who were working in the Wuhan area reported experiencing more anxiety (p = 0.038) and perceived stress (p < 0.001) compared with those who were not working in the Wuhan area. The frontline dental medical staff who were working in a general hospital reported experiencing more dissociation symptoms (p = 0.001) compared with those working in a specialized or private hospital. Individuals with a past medical history reported experiencing more anxiety (p = 0.009), depression (p < 0.001), and perceived stress (p = 0.003) than those without, and individuals with lower levels of education showed higher levels of anxiety (p = 0.038). Binary logistic regression analysis results (after controlling for other confounders) suggested that having a past medical history was a risk factor for both anxiety (p = 0.002; OR = 2.441; 95% CI, 1.384–4.306) and perceived stress (p = 0.001; OR = 1.417; 95% CI, 1.145–1.754).Conclusions: The prevalence of mental symptoms was high among the first-line emergency dental staff. Male sex, working in the Wuhan area, working in a general hospital, a past medical history, and lower levels of education were risk factors. Therefore, we need to pay close attention to the mental health problems of frontline dentists during the COVID-19 outbreak and adopt active preventive strategies to maintain their physical and mental health.

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Section: Discussionmentioning

confidence: 69%

Influencing Factors Associated With Mental Health Outcomes Among Dental Medical Staff in Emergency Exposed to Coronavirus Disease 2019: A Multicenter Cross-Sectional Study in China

Chen

2021

Front. Psychiatry

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“…Prior studies have shown that in geriatric chronically institutionalized schizophrenia patients, only those with better cognitive functioning tend to manifest any substantial symptoms of depression (Chemerinski et al, 2008). Similarly, D’Antonio and Serper (2012) found that depression was associated with better cognitive functioning, but was unassociated with everyday functioning ratings in a sample of geriatric hospitalized patients. The relationship between insight into illness and depression seems complex.…”

Section: Discussionmentioning

confidence: 90%

Predictors of the accuracy of self assessment of everyday functioning in people with schizophrenia

Sabbag

Twamley

Vella

et al. 2012

Schizophrenia Research

111

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Despite multiple lines of evidence suggesting that people with schizophrenia have substantial problems in self-reporting everyday functioning and cognitive performance, self-report methods are still widely used to assess functioning. This study attempted to identify predictors of accuracy in self report, both in terms of accurate self-assessment and over-estimation of current functioning. As part of the larger Validating Assessments of Everyday Real-World Outcomes (VALERO) study, 195 patients with schizophrenia were asked to self report their everyday functioning with the Specific Levels of Functioning (SLOF) scale, which includes subscales assessing social functioning, everyday activities, and vocational functioning. They were also assessed with measures of neuropsychological (NP) performance and functional capacity (FC), and were assessed for psychiatric symptomatology. In addition, a friend, relative or clinician informant was interviewed with the SLOF, and an interviewer with access to all information provided by the patient and informant (exclusive of performance-based data) generated “best estimate” ratings of actual, everyday functioning. Patients significantly (p<.001) overestimated their vocational functioning and everyday activities compared to the interviewer judgments. Lower levels of NP and FC performance and everyday functioning on the part of patients were consistently associated with overestimation of their functioning. Patient self-reports were not correlated with any performance-based measures, while interviewer judgments were significantly correlated with patients’ performance on NP and FC measures (p<.005). In regression analyses, adjusting for interviewer ratings of functioning, several predictors of the discrepancy between self and interviewer judgments emerged. Higher levels of depressive symptoms were associated with less overestimation in self-reports (p<.001). Delusions, suspiciousness, grandiosity and poor rapport were all significantly (p<.001) associated with over-estimation of functioning compared to interviewer judgments. Poorer NP and FC performance were also associated with over-estimation of everyday functioning, but these results were not statistically significant in multivariate regression models. Consistent with previous studies in schizophrenia, other neuropsychiatric conditions and non-clinical populations, higher levels of depression were associated with increased accuracy in self-assessment. Similarly, lower scores on performance-based measures and judgments of everyday functioning also predicted over-estimation of functioning. Thus, we identified bi-directional predictors of mis-estimation of everyday functioning, even when poor baseline scores were considered. These data suggest that it may be possible to screen patients for their ability to self-report their functioning, but that performance-based measures of functioning provide a less biased assessment.

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“…Исследования связи депрессивных расстройств с шизофренией проводилось и в странах Юго-Восточной Азии (Китай [17,30,57,59], Корея [32,51,58], Тайвань [33], Япония [41,43,52]), в которые было суммарно включено 2436 пациентов с шизофренией, в том числе: 1211 (46,1%) мужчин и 1315 (53,9%) женщин. Возраст пациентов варьировал от 16 до 75 лет, средний возраст составил 37,6 лет.…”

Section: Research Reviews научные обзорыunclassified

“…-в Африке[11,12,40]; 4 -в Тихоокеанском регионе[21,22,53, 54]; 11 -в Юго-Восточной Азии[17,30,32,33,41,43,51,52, 57, 58, 59]; 4 -на Ближнем Востоке[11,44,45,46] -Табл.1, Табл.2.…”

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The incidence of depressive disorders in patients with schizophrenia

Новицкий

Шнайдер

Насырова

2021

V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY

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Summary. Introduction. Historically, depressive disorders have been described in various forms of schizophrenia by Kraepelin (1923) or as a reaction to illness by Bleuler (1922). One of the alternative points of view that has been considered in recent years is that depressive disorders are a comorbid condition of schizophrenia or one of the manifestations of schizophrenia. However, to date, depression, as a symptom, is not included in the diagnostic criteria of the ICD-10. Methodological approaches to diagnosing depressive disorders in patients with schizophrenia differ in different countries and research groups. This influences the prevalence rates of depressive disorders in schizophrenic patients. Purpose. The study and systematization of studies of the incidence of depressive disorders in patients with schizophrenia.Methods. Russian-language and foreign literature was analyzed with a search depth of 10 years (2010–2020) in the following databases: PubMed, Springer, Wiley Online Library, Taylor & Francis Online, US National Library of Medicine National Institutes of Health, Science Direct and eLIBRARY .RU.Results. A total of 51 studies of depressive disorders in children and adults with schizophrenia were found.Conclusion. The frequency of occurrence of depressive disorders in patients with schizophrenia varies from 9.1 and to 100%, the average frequency is 41.6%. Their frequency is variable and depends on the region of residence and ethnicity. It is noted that depressive disorders in patients with schizophrenia are more often recorded among residents of the Middle East (72.7%), Russia (61.8%) and Europe (39.6%), less often among residents of Southeast Asia (32%) and the Pacific region ( 37.3%). The countries with the highest incidence of depressive disorders in schizophrenia include: USA, Germany, China; and to the countries with the lowest frequency — Denmark, Israel, South Africa. Also, I would like to note that the largest number of studies conducted was in Europe (16 studies with 36 928 patients with schizophrenia), the USA (6 studies with 2314 patients) and the Russian Federation (6 studies with 582 patients). In general, in the world, according to 51 studies analyzed, the incidence of depressive disorders in schizophrenia in men is higher than in women, although gender differences did not reach statistical significance in all regions of the world.

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Depression and cognitive deficits in geriatric schizophrenia

Cited by 13 publications

References 37 publications

Influencing Factors Associated With Mental Health Outcomes Among Dental Medical Staff in Emergency Exposed to Coronavirus Disease 2019: A Multicenter Cross-Sectional Study in China

Influencing Factors Associated With Mental Health Outcomes Among Dental Medical Staff in Emergency Exposed to Coronavirus Disease 2019: A Multicenter Cross-Sectional Study in China

Predictors of the accuracy of self assessment of everyday functioning in people with schizophrenia

The incidence of depressive disorders in patients with schizophrenia

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