Depression and prostate cancer: A focused review for the clinician

Fervaha, Gagan; Izard, Jason; Tripp, Dean A.; Rajan, Selina; Leong, Darryl P.; Siemens, D. Robert

doi:10.1016/j.urolonc.2018.12.020

Cited by 76 publications

(128 citation statements)

References 53 publications

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“…5 In light of the growing emphasis placed on cancer survivorship, evidence presented here, further supports the critical need for intervention early on and during PCa survivorship. 5 In light of the growing emphasis placed on cancer survivorship, evidence presented here, further supports the critical need for intervention early on and during PCa survivorship.…”

Section: Covariatessupporting

confidence: 57%

“…5 In light of the growing emphasis placed on cancer survivorship, evidence presented here, further supports the critical need for intervention early on and during PCa survivorship. 5 The reliance on self-reported data represent a potential limitation. 5 The reliance on self-reported data represent a potential limitation.…”

Section: Covariatessupporting

confidence: 57%

“…2 With a growing aging Canadian population and an increase in PCa detection among asymptomatic men the incidence rates of PCa are predicted to remain high in the decades to come. 5,6 Anxiety and depression are the most common psychological conditions affecting cancer patients and survivors. Although mental health is a critical component of PCa survivorship, it is largely understudied.…”

Section: Introductionmentioning

confidence: 99%

“…3,4 As such, the management of PCa survivorship issues is becoming increasingly critical. 5,6 Previous studies have identified that the prevalence of anxiety and depression are higher among PCa survivors than that among survivors of other forms of cancer, but typically these studies have focused on rates of mental health during diagnosis or treatment rather than long term survivorship. 5,6 Anxiety and depression are the most common psychological conditions affecting cancer patients and survivors.…”

Section: Introductionmentioning

confidence: 99%

“…5,6 Previous studies have identified that the prevalence of anxiety and depression are higher among PCa survivors than that among survivors of other forms of cancer, but typically these studies have focused on rates of mental health during diagnosis or treatment rather than long term survivorship. 5,8 Several relevant contributing factors for mental health have been identified including functional (erectile, urinary and/or bowel dysfunction), psychological (anxiety, stress, depressive symptoms, learned helplessness, lack of cognitive reframing strategies), and social issues (being single, lack of social support or choosing social isolation). 5 Anxiety and depression considerably affect survivors' overall quality of life, adherence to ongoing treatment and therapies, and have been shown to negatively influence disease progression and negatively affectthe oncological outcomes.…”

Section: Introductionmentioning

confidence: 99%

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Anxiety and depression symptoms in adult males in Atlantic Canada with or without a lifetime history of prostate cancer

2019

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Section: Covariatessupporting

confidence: 57%

“…5 In light of the growing emphasis placed on cancer survivorship, evidence presented here, further supports the critical need for intervention early on and during PCa survivorship. 5 The reliance on self-reported data represent a potential limitation. 5 The reliance on self-reported data represent a potential limitation.…”

Section: Covariatessupporting

confidence: 57%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Anxiety and depression symptoms in adult males in Atlantic Canada with or without a lifetime history of prostate cancer

2019

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Effects of group logotherapy on mood and function of locally advanced prostate cancer patients

Arefpour

Mahdavi

2021

Couns and Psychother Res

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Patients with prostate cancer who receive systemic androgen deprivation therapy (ADT) and local treatments have a high likelihood to experience depression, anxiety and fatigue. The present study aimed to determine the effects of Frankl's group logotherapy sessions on alleviating these symptoms in individuals with moderate-to highrisk prostate cancer who were receiving pelvic radiotherapy. A quasi-experimental study with pretest-post-test was conducted in which 30 patients were assigned either to the experimental (n = 15) or to the control (n = 15) group. The implicated research instruments were as follows: Beck's Depression Inventory, Beck's Anxiety Inventory, Okayama et al.'s Cancer Fatigue Scale and Luthans' Psychological Capital Questionnaire. The results of the ANCOVA showed that logotherapy significantly affected anxiety (F = 42.51, p < 0.001), depression (F = 39.36, p < 0.001), cancer fatigue (F = 16.54, p < 0.001) and psychological capital (F = 39.86, p < 0.001) in the experimental group compared to the control group, indicating that logotherapy sessions with an emphasis on meanings, aims and values of life, when accompanied by peer interaction, can improve mood and function as well as contributing to positive psychological capital in intermediate and high-risk prostate cancer patients during their treatments.

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Long‐term depression incidence and associated mortality among African American and White prostate cancer survivors

Parikh

Gallo

Wong

et al. 2021

Cancer

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Background Depression is common after a diagnosis of prostate cancer and may contribute to poor outcomes, particularly among African Americans. The authors assessed the incidence and management of depression and its impact on overall mortality among African American and White veterans with localized prostate cancer. Methods The authors used the Veterans Health Administration Corporate Data Warehouse to identify 40,412 African American and non‐Hispanic White men diagnosed with localized prostate cancer from 2001 to 2013. Patients were followed through 2019. Multivariable logistic regression was used to measure associations between race and incident depression, which were ascertained from administrative and depression screening data. Cox proportional hazards models were used to measure associations between incident depression and all‐cause mortality, with race‐by‐depression interactions used to assess disparities. Results Overall, 10,013 veterans (24.5%) were diagnosed with depression after a diagnosis of prostate cancer. Incident depression was associated with higher all‐cause mortality (adjusted hazard ratio [aHR], 1.27; 95% confidence interval [CI], 1.23‐1.32). African American veterans were more likely than White veterans to be diagnosed with depression (29.3% vs 23.2%; adjusted odds ratio [aOR], 1.15; 95% CI, 1.09‐1.21). Among those with depression, African Americans were less likely to be prescribed an antidepressant (30.4% vs 31.7%; aOR, 0.85; 95% CI, 0.77‐0.93). The hazard of all‐cause mortality associated with depression was greater for African American veterans than White veterans (aHR, 1.32 [95% CI, 1.26‐1.38] vs 1.15 [95% CI, 1.07‐1.24]; race‐by‐depression interaction P < .001). Conclusions Incident depression is common among prostate cancer survivors and is associated with higher mortality, particularly among African American men. Patient‐centered strategies to manage incident depression may be critical to reducing disparities in prostate cancer outcomes.

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Depression and prostate cancer: A focused review for the clinician

Cited by 76 publications

References 53 publications

Anxiety and depression symptoms in adult males in Atlantic Canada with or without a lifetime history of prostate cancer

Anxiety and depression symptoms in adult males in Atlantic Canada with or without a lifetime history of prostate cancer

Effects of group logotherapy on mood and function of locally advanced prostate cancer patients

Long‐term depression incidence and associated mortality among African American and White prostate cancer survivors

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