In this paper, I have focused upon the ethno psychology of depression. The term "ethno psychology" refers to indigenous representations of mind, body, emotion and self. In the past two decades, anthropologists, psychologists and psychiatrists have become increasingly interested in the role of culture for the expression and experience of depression. I shall argue that the constellation of ethno psychological features, deeply rooted in their culture make up of culture members, influences the ways in which individuals experience and express depression, as it does for all emotions. Different cultural conceptions of self and emotion result in variations in the qualitative features of bodily/emotional experience, and thus dysphoric affects cannot be considered the same cross-culturally. The literature pertaining to culture and depression is still dominated by studies based upon Western-based diagnostic criteria and examines the incidence and prevalence rates of this disorder. While anthropologists tend to view depression as an affect, psychiatrists view it as an affective disorder. Keyes 1 asserts that biomedicine is unique as it deals with illness by interpreting experience without reference to the problem of suffering. Kirmayer 2 argues that the Diagnostic and Statistical Manual of Mental Disorders (DSM), reflects cultural values of personal autonomy and to uniqueness of each individual and the significance of personal aims, goals, values and preferences. However, there is a lack of emphasis on interpersonal symptoms. Some have argued that the term "profound distress" may be preferable to the term "depressive disorder". 3 Indeed unlike other medical conditions, Ryder et al 4 maintains that depression emerges from a complex interplay of culture, mind and brain which is not reducible to any single level. The experience, meaning and expression of dysphoria-referring to sadness, hopelessness, unhappiness and lack of pleasure-varies across cultural groups. 5