Depression as a Risk Factor for Relapse After Inpatient Opioid Detoxification: 1-Year Follow-Up Study

Chalana, Harsh; Kundal, Tanu; Malhari, Amandeep Singh

doi:10.5812/ijhrba.59543

Cited by 3 publications

(7 citation statements)

References 11 publications

(13 reference statements)

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“…For better efficacy of treatment, our physicians should consider the adequacy of methadone dosage, especially in patients with history of multiple previous treatments. In our study, patients with history of psychiatric diseases had lower adherence to MMT which was compatible with similar studies [15][16][17][18][19]. Chalana et al [15] found after inpatient opioid detoxification, patients with higher score on the depression scale had higher rate of relapse.…”

Section: Discussionsupporting

confidence: 91%

Adherence to Methadone Maintenance Treatment and its Predictors in Southeast of Iran

Ahmadipour

2018

GJARM

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This cross-sectional study carried out on 334 patients referred to the rehab centers in Sirjan (The second largest county in Kerman province, south east of Iran) during 2017. Participants were selected through the multistage random sampling method. Ten of the 24 rehab centers were selected randomly and in each centers 33 clients were selected using convenient sampling method. The study was approved by the research review

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Section: Discussionsupporting

confidence: 91%

Adherence to Methadone Maintenance Treatment and its Predictors in Southeast of Iran

Ahmadipour

2018

GJARM

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“…Depression is referred to at least two weeks of depressed mood, apathy, and lack of pleasure in everything (6). Chalana et al (2017) (7), in a one-year follow-up study of addicts on treatment, showed that people with recurrent relapses reported a depression score almost twice the other group, and more than 16% of them had very severe depression. Tendency to use drugs is a coping strategy.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Acceptance and Commitment Therapy in Depression and Anxiety in People with Substance Use Disorder

Hashemi

Einy²,

Ebadi

2022

Iran J Psychiatry Behav Sci

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Background: The comorbidity of substance use, mood disorders, and anxiety has been proven in various studies, leading to many clinical implications. Objectives: This study aimed to evaluate the effectiveness of acceptance and commitment therapy (ACT) in depression and anxiety in individuals with substance use disorder. Methods: This quasi-experimental study utilized a pretest-posttest design with a control group. The statistical population consisted of all people with substance abuse in Urmia in 2019, including 220 subjects. The sample consisted of 50 individuals with substance use disorders selected by purposive sampling and randomly assigned to experimental and control groups. The experimental group was trained in eight sessions, each lasting 90 min, based on the ACT protocol by Hayes et al. (2004), while the control group did not receive any intervention. The data were obtained using the Beck Depression Inventory and Beck Anxiety Inventory. Pretest and posttest were performed in both groups. The collected data were analyzed by multivariate analysis of covariance (MANCOVA) using SPSS23 software. Results: The results showed that after controlling for the pretest effects, a significant difference was observed between the mean posttest scores of the two groups in both depression and anxiety (P < 0.05). Conclusions: Acceptance and commitment therapy is an appropriate strategy to effectively improve depression and anxiety in people with substance use disorder.

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“…Opioid use disorder continues to be a significant public health problem around the world. Opioid addiction is a chronic relapsing condition with multiple complex consequences (1). Opioids can be divided into natural opioids (morphine, codeine, and thebaine), semi-synthetic opioids (heroin, hydromorphone, hydrocodone, and oxycodone), and fully synthetic opioids (fentanyl, pethidine, levorphanol, methadone, tramadol, and dextropropoxyphene) (2).In Malaysia, it is estimated that the prevalence of opioid demand for 2018was the highest compared to other substances (3).…”

Section: Introductionmentioning

confidence: 99%

“…A recent study conducted at a government hospital methadone center found that 36.5% of patients relapse 6 months after joining the MMT program (9). Globally, relapse among those who underwent detoxification programs ranges from 20% to 80% (1,13,16,20,21).…”

Section: Introductionmentioning

confidence: 99%

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Prediction of Relapse Among Individuals Undergoing Methadone Maintenance Therapy in Johor Bahru Health District

Mohmad¹,

Suriani²,

Manaf³

2022

MJMHS

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Introduction: Increase in the number of opioids seized in the recent year may indicate increased opioid use in Malaysia. In counteracting opioid abuse, Methadone Maintenance Therapy (MMT) was introduced in Malaysia but relapse following MMT has become an important issue. This study aimed to determine the prevalence and patient factors that served as predictors of opioid relapse among MMT patients. Method: A cross-sectional study involving 159 MMT patients who have reached dose stabilization (eight weeks at a constant dose of methadone) was conducted in Johor Bahru Health District. The dependent variable was opioid relapse, while the independent variables include socio-demographic characteristics, MMT history, crime history, cognitive and interpersonal factors, and social-environment influence. Face-to-face interviews using structured questionnaires and secondary data collection using data collection sheets were done. Multiple logistic regression was used to determine the predictors. Significant level set at alpha less than 5%. Result: The response rate was 86.9% with majority of them were Malay, male, and Muslim. The prevalence of opioid relapse was 11.9%. Those who were non-polydrug users (AOR=3.701, 95%CI=1.182, 11.587, p=0.025), classified as having moderate (AOR=5.869, 95%CI=1.524, 22.595, p=0.010) and high (AOR=5.952, 95%CI=1.000, 35.445, p=0.050) relapse risk response after given hypothetical situation whether respondent been offered drug or not, were more likely to have relapsed. Respondents with higher cognitive and behavioral problem-solving response scores were less likely to have relapsed (AOR=0.949, 95%CI=0.909, 0.991, p=0.008). Conclusion: About 1 in 5 MMT clients had relapsed after they reach dose stabilization. The predictors of opioid relapse were non-polydrug users, having moderate to high relapse risk, and cognitive and behavioral problem-solving responses.

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Depression as a Risk Factor for Relapse After Inpatient Opioid Detoxification: 1-Year Follow-Up Study

Cited by 3 publications

References 11 publications

Adherence to Methadone Maintenance Treatment and its Predictors in Southeast of Iran

Adherence to Methadone Maintenance Treatment and its Predictors in Southeast of Iran

Effectiveness of Acceptance and Commitment Therapy in Depression and Anxiety in People with Substance Use Disorder

Prediction of Relapse Among Individuals Undergoing Methadone Maintenance Therapy in Johor Bahru Health District

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